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Glutamate [NMDA] Receptor Subunit Zeta-1 (GRIN1) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS949414

MBS949414 is a recombinant protein targeting Grin1. Also known as Recombinant Rat Glutamate [NMDA] receptor subunit zeta-1 (Grin1) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$330 / 0.02 mg (Yeast) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glutamate [NMDA] receptor subunit zeta-1 (Grin1), Recombinant Protein
Full Product Name
Recombinant Rat Glutamate [NMDA] receptor subunit zeta-1 (Grin1) , partial
Product Gene Name
Sequence
RAACDPKIVN IGAVLSTRKH EQMFREAVNQ ANKRHGSWKI QLNATSVTHK PNAIQMALSV CEDLISSQVY AILVSHPPTP NDHFTPTPVS YTAGFYRIPV LGLTTRMSIY SDKSIHLSFL RTVPPYSHQS SVWFEMMRVY NWNHIILLVS DDHEGRAAQK RLETLLEERE SKAEKVLQFD PGTKNVTALL MEARELEARV IILSASEDDA ATVYRAAAML NMTGSGYVWL VGEREISGNA LRYAPDGIIG LQLINGKNES AHISDAVGVV AQAVHELLEK ENITDPPRGC VGNTNIWKTG PLFKRVLMSS KYADGVTGRV EFNEDGDRKF ANYSIMNLQN RKLVQVGIYN GTHVIPNDRK IIWPGGETEK PRGYQMSTRL KIVTIHQEPF VYVKPTMSDG TCKEEFTVNG DPVKKVICTG PNDTSPGSPR HTVPQCCYGF CIDLLIKLAR TMNFTYEVHL VADGKFGTQE RVNNSNKKEW NGMMGELLSG QADMIVAPLT INNERAQYIE FSKPFKYQGL TILVKKEIPR STLDSFMQPF Q
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
101,987 Da
Sequence Positions
19-559aa; Partial
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P35439
Species
Rattus norvegicus (Rat)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Grin1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Grin1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
glutamate receptor ionotropic, NMDA 1 isoform 1b
NCBI Official Synonym Full Names
glutamate ionotropic receptor NMDA type subunit 1
NCBI Official Symbol
Grin1
NCBI Official Synonym Symbols
NR1; GluN1; NMDAR1
UniProt Protein Name
Glutamate receptor ionotropic, NMDA 1
UniProt Synonym Protein Names
Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1
UniProt Gene Name
Grin1
UniProt Synonym Gene Names
; NMD-R1
NCBI Protein Information
glutamate receptor ionotropic, NMDA 1

NCBI Summary for Grin1

subunit of NMDA-preferring ionotropic glutamate receptors; may play a role in long term potentiation [RGD, Feb 2006]

UniProt Comments for Grin1

Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+ (PubMed:1350383, PubMed:1834949, PubMed:1388270, PubMed:8428958, PubMed:18177891, PubMed:28384476, PubMed:15996549, PubMed:24876489, PubMed:27135925, PubMed:27618671, PubMed:28468946). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:28384476).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with Grin1 recombinant protein

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