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Fatty Acid-Binding Protein (FABP1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS949832

Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. More details

$410 / 0.2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Fatty acid-binding protein (FABP1), Recombinant Protein
Full Product Name
Recombinant Human Fatty acid-binding protein, liver
Product Gene Name
FABP1 recombinant protein
Product Synonym Names
Fatty acid-binding protein 1; Liver-type fatty acid-binding protein; L-FABP
Sequence
MSFSGKYQLQ SQENFEAFMK AIGLPEELIQ KGKDIKGVSE IVQNGKHFKF TITAGSKVIQ NEFTVGEECE LETMTGEKVK TVVQLEGDNK LVTTFKNIKS VTELNGDIIT NTMTLGDIVF KRISKRI
Form/Format
Liquid containing glycerol
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Molecular Weight
41.6kD
Sequence Positions
1-127
OMIM
134650
3D Structure
ModBase 3D Structure for P07148
Product Note
Applications are user defined. Product is developed and quality control tested in house, data or additional information may be provided upon request. The researcher needs to establish and confirm the suitability of the product for their application.

Product Categories/Family for FABP1 recombinant protein

Transport; Raw Materials Assay Development
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

SDS-Page of FABP1 recombinant protein

Human FABP1 Recombinant Protein – Cat# MBS949832

Product References and Citations for FABP1 recombinant protein

Human liver fatty acid binding protein cDNA and amino acid sequence. Functional and evolutionary implications.Chan L., Wei C.-F., Li W.-H., Yang C.-Y., Ratner P., Pownall H., Gotto A.M. Jr., Smith L.C.J. Biol. Chem. 260:2629-2632(1985) Human liver fatty acid binding protein. Isolation of a full length cDNA and comparative sequence analyses of orthologous and paralogous proteins.Lowe J.B., Boguski M.S., Sweetser D.A., Elshourbagy N.A., Taylor J.M., Gordon J.I.J. Biol. Chem. 260:3413-3417(1985) Initial characterization of the human central proteome.Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011) An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014) Rapid data collection for protein structure determination by NMR spectroscopy.Xu Y., Long D., Yang D.J. Am. Chem. Soc. 129:7722-7723(2007) Crystal structure of human FABP1.Structural genomics consortium (SGC) Submitted (DEC-2005) to the PDB data bank

Other Notes

Small volumes of FABP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FABP1 purchase

MBS949832 is a recombinant protein targeting FABP1. Also known as Recombinant Human Fatty acid-binding protein, liver.

Additional Details

NCBI/Uniprot data below describe general gene information for FABP1. It may not necessarily be applicable to this product.

NCBI GI #
4557577
NCBI GeneID
2168
NCBI Accession #
NP_001434.1
UniProt Primary Accession #
P07148
UniProt Related Accession #
P07148
GenBank Nucleotide #
NM_001443.2
NCBI Official Full Name
fatty acid-binding protein, liver
NCBI Official Synonym Full Names
fatty acid binding protein 1
NCBI Official Symbol
FABP1
NCBI Official Synonym Symbols
FABPL; L-FABP
UniProt Protein Name
Fatty acid-binding protein, liver
UniProt Synonym Protein Names
Fatty acid-binding protein 1; Liver-type fatty acid-binding protein; L-FABP
Protein Family
Fatty acid-binding protein
UniProt Gene Name
FABP1
UniProt Synonym Gene Names
FABPL; L-FABP
UniProt Entry Name
FABPL_HUMAN
NCBI Protein Information
fatty acid-binding protein, liver

NCBI Summary for FABP1

This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011]
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UniProt Comments for FABP1

FABP1: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 2p11

Cellular Component: apical cortex; cytoplasm; cytosol; nucleoplasm; peroxisomal matrix

Molecular Function: antioxidant activity; bile acid binding; chromatin binding; drug binding; fatty acid binding; long-chain fatty acid transporter activity; phospholipid binding; protein binding

Biological Process: cellular lipid metabolic process; intestinal absorption; long-chain fatty acid transport; negative regulation of apoptosis; negative regulation of caspase activity; positive regulation of cell proliferation; positive regulation of defense response to virus by host; positive regulation of fatty acid beta-oxidation; positive regulation of hydrolase activity; triacylglycerol catabolic process
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Research Articles on FABP1

1. Measurement of uL-FABP levels at 48 h after coronary angiography may be useful in detecting renal damage, and in predicting 1-year renal outcome in ischemic heart disease patients undergoing CAG.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FABP1 recombinant protein

 Reference Product  PubMed Publications
 HNF1A recombinant protein  >9 publications with FABP1 and HNF1A
 CPT1A recombinant protein  >6 publications with FABP1 and CPT1A
 LPL recombinant protein  >5 publications with FABP1 and LPL
 ACOX1 recombinant protein  >4 publications with FABP1 and ACOX1
 EHHADH recombinant protein  >2 publications with FABP1 and EHHADH
 PPARA recombinant protein  >2 publications with FABP1 and PPARA
 APOA1 recombinant protein  >1 publications with FABP1 and APOA1

Pathways associated with FABP1 recombinant protein

 Products by Pathway  Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Hormone-sensitive Lipase (HSL)-mediated Triacylglycerol Hydrolysis Pathway antibodies  Hormone-sensitive Lipase (HSL)-mediated Triacylglycerol Hydrolysis Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram

Diseases associated with FABP1 recombinant protein

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >370 publications with FABP1 and Fatty Liver
 Kidney Diseases Antibodies  >100 publications with FABP1 and Kidney Diseases
 Liver Diseases Antibodies  >80 publications with FABP1 and Liver Diseases
 Acute Kidney Injury Antibodies  >60 publications with FABP1 and Acute Kidney Injury
 Cardiovascular Diseases Antibodies  >38 publications with FABP1 and Cardiovascular Diseases
 Proteinuria Antibodies  >33 publications with FABP1 and Proteinuria
 Liver Neoplasms Antibodies  >32 publications with FABP1 and Liver Neoplasms
 Inflammation Antibodies  >27 publications with FABP1 and Inflammation
 Hypertension Antibodies  >20 publications with FABP1 and Hypertension
 Necrosis Antibodies  >16 publications with FABP1 and Necrosis

Organs/Tissues associated with FABP1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >381 publications with FABP1 and Liver
 Kidney Antibodies  >118 publications with FABP1 and Kidney
 Intestine Antibodies  >99 publications with FABP1 and Intestine
 Muscle Antibodies  >30 publications with FABP1 and Muscle
 Stomach Antibodies  >12 publications with FABP1 and Stomach
 Embryonic Tissue Antibodies  >10 publications with FABP1 and Embryonic Tissue
 Lung Antibodies  >8 publications with FABP1 and Lung
 Placenta Antibodies  >7 publications with FABP1 and Placenta
 Prostate Antibodies  >3 publications with FABP1 and Prostate
 Mammary Gland Antibodies  >1 publications with FABP1 and Mammary Gland
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