• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Alpha-1b Adrenergic Receptor (ADRA1B) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS950068

MBS950068 is a recombinant protein targeting Adra1b. Also known as Recombinant Rat Alpha-1B adrenergic receptor (Adra1b). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. Adra1b More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Alpha-1B adrenergic receptor (Adra1b), Recombinant Protein
Full Product Name
Recombinant Rat Alpha-1B adrenergic receptor (Adra1b)
Product Gene Name
Adra1b recombinant protein
Product Synonym Gene Name
Recombinant Alpha-1B adrenergic receptor (Adra1b); Alpha-1B adrenergic receptor; Alpha-1B adrenoreceptor; Alpha-1B adrenoceptor
Sequence
MNPDLDTGHN TSAPAHWGEL KDDNFTGPNQ TSSNSTLPQL DVTRAISVGL VLGAFILFAI VGNILVILSV ACNRHLRTPT NYFIVNLAIA DLLLSFTVLP FSATLEVLGY WVLGRIFCDI WAAVDVLCCT ASILSLCAIS IDRYIGVRYS LQYPTLVTRR KAILALLSVW VLSTVISIGP LLGWKEPAPN DDKECGVTEE PFYALFSSLG SFYIPLAVIL VMYCRVYIVA KRTTKNLEAG VMKEMSNSKE LTLRIHSKNF HEDTLSSTKA KGHNPRSSIA VKLFKFSREK KAAKTLGIVV GMFILCWLPF FIALPLGSLF STLKPPDAVF KVVFWLGYFN SCLNPIIYPC SSKEFKRAFM RILGCQCRGG RRRRRRRRLG ACAYTYRPWT RGGSLERSQS RKDSLDDSGS CMSGTQRTLP SASPSPGYLG RGTQPPVELC AFPEWKPGAL LSLPEPPGRR GRLDSGPLFT FKLLGDPESP GTEGDTSNGG CDTTTDLANG QPGFKSNMPL APGHF
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
56,586 Da
Sequence Positions
1-515
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 10; NC_005109.3 (29233972..29291344, complement). Location: 10q21
3D Structure
ModBase 3D Structure for P15823
Species
Rattus norvegicus (Rat)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Adra1b recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Adra1b. It may not necessarily be applicable to this product.

NCBI GI #
543734
NCBI GeneID
24173
NCBI Accession #
P15823.2
UniProt Primary Accession #
P15823
UniProt Secondary Accession #
Q63215
UniProt Related Accession #
P15823
NCBI Official Full Name
Alpha-1B adrenergic receptor
NCBI Official Synonym Full Names
adrenoceptor alpha 1B
NCBI Official Symbol
Adra1b
UniProt Protein Name
Alpha-1B adrenergic receptor
UniProt Synonym Protein Names
Alpha-1B adrenoreceptor
Protein Family
Alpha-1B adrenergic receptor
UniProt Gene Name
Adra1b
UniProt Synonym Gene Names
Alpha-1B adrenoceptor
UniProt Entry Name
ADA1B_RAT
NCBI Protein Information
alpha-1B adrenergic receptor; alpha 1B-adrenoceptor; alpha-1B adrenoceptor; alpha 1B-adrenoreceptor; alpha-1B adrenoreceptor; Adrenergic alpha 1B- receptor; adrenergic receptor, alpha 1b; adrenergic, alpha-1B-, receptor

NCBI Summary for Adra1b

couples with G alpha(h) (transglutaminase II) to activate phospholipase C; facilitates Ca2+ release and capacitative Ca2+ entry [RGD, Feb 2006]

UniProt Comments for Adra1b

ADRA1B: a G protein-coupled catecholamine receptor that activates mitogenic responses and regulates growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. Can induce neoplastic transformation when transfected into cell lines. Can regulate the phosphorylation status of the STAT3 pathway. Mediates blood pressure and aorta contractile responses induced by alpha-1 agonists. Activates a phosphatidylinositol second messenger system.

Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass

Cellular Component: nuclear membrane; membrane; T-tubule; integral to membrane; nucleus

Molecular Function: protein heterodimerization activity; alpha1-adrenergic receptor activity

Biological Process: response to drug; adult heart development; vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure; positive regulation of the force of heart contraction by epinephrine-norepinephrine; response to amphetamine; response to hormone stimulus; response to morphine; locomotory behavior; glucose homeostasis; positive regulation of glycogen catabolic process; organ growth; elevation of cytosolic calcium ion concentration; negative regulation of Rho protein signal transduction; positive regulation of MAPKKK cascade; response to estrogen stimulus; response to steroid hormone stimulus; behavioral response to cocaine; regulation of vasoconstriction; visual learning; blood vessel remodeling; cell growth; positive regulation of heart rate by epinephrine-norepinephrine; negative regulation of glycogen catabolic process
Show more

Research Articles on Adra1b

1. alpha- and beta-adrenergic signalling has a role in epinephrine-dependent control of glucose metabolism in white adipose tissue

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Adra1b recombinant protein

 Reference Product  PubMed Publications
 Nos1 recombinant protein  >6 publications with Adra1b and Nos1
 C1qbp recombinant protein  >1 publications with Adra1b and C1qbp

Pathways associated with Adra1b recombinant protein

 Products by Pathway  Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Monoamine GPCRs Pathway antibodies  Monoamine GPCRs Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Salivary Secretion Pathway antibodies  Salivary Secretion Pathway Diagram
 Salivary Secretion Pathway antibodies  Salivary Secretion Pathway Diagram
 Vascular Smooth Muscle Contraction Pathway antibodies  Vascular Smooth Muscle Contraction Pathway Diagram

Organs/Tissues associated with Adra1b recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >1761 publications with Adra1b and Heart
 Uncharacterized Tissue Antibodies  >2 publications with Adra1b and Uncharacterized Tissue
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000