Mouse G3BP1 Recombinant Protein – Cat# MBS950484

Ras Gtpase-Activating Protein-Binding Protein 1 (G3BP1) Mouse Recombinant Protein

Name: G3BP1 Recombinant Protein; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS950484
Price: 1240 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS950484

This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3 -tailed substrates and can also unwind partial RNADNA and RNARNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding… More details

$1240 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ras GTPase-activating protein-binding protein 1 (G3bp1), Recombinant Protein

Full Product Name

Recombinant Mouse Ras GTPase-activating protein-binding protein 1 (G3bp1)

Product Gene Name

G3bp1 recombinant protein

Sequence

VMEKPSPLLV GREFVRQYYT LLNQAPDMLH RFYGKNSSYA HGGLDSNGKP ADAVYGQKEI HRKVMSQNFT NCHTKIRHVD AHATLNDGVV VQVMGLLSNN NQALRRFMQT FVLAPEGSVA NKFYVHNDIF RYQDEVFGGF VTEPQEESEE EVEEPEERQQ TPEVVPDDSG TFYDQTVSND LEEHLEEPVV EPEPEPEPEP EPEPVSDIQE DKPEAALEEA APDDVQKSTS PAPADVAPAQ EDLRTFSWAS VTSKNLPPSG AVPVTGTPPH VVKVPASQPR PESKPDSQIP PQRPQRDQRV REQRINIPPQ RGPRPIREAG EPGDVEPRRM VRHPDSHQLF IGNLPHEVDK SELKDFFQNF GNVVELRINS GGKLPNFGFV VFDDSEPVQK VLSNRPIMFR GAVRLNVEEK KTRAAREGDR RDNRLRGPGG PRGGPSGGMR GPPRGGMVQK PGFGVGRGIT TPRQ

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

51,829 Da

Sequence Positions

2-465, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for P97855

Species

Mouse

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of G3bp1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for G3bp1 purchase

MBS950484 is a recombinant protein targeting G3bp1. Also known as Recombinant Mouse Ras GTPase-activating protein-binding protein 1 (G3bp1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for G3bp1. It may not necessarily be applicable to this product.

NCBI GI #

7305075

NCBI GeneID

27041

NCBI Accession #

NP_038744.1

UniProt Primary Accession #

P97855

UniProt Related Accession #

P97855

GenBank Nucleotide #

NM_013716.2

NCBI Official Full Name

ras GTPase-activating protein-binding protein 1

NCBI Official Synonym Full Names

GTPase activating protein (SH3 domain) binding protein 1

NCBI Official Symbol

G3bp1

NCBI Official Synonym Symbols

G3bp; C87777; AI849976; mKIAA4115; B430204O07

UniProt Protein Name

Ras GTPase-activating protein-binding protein 1

UniProt Synonym Protein Names

ATP-dependent DNA helicase VIII; GAP SH3 domain-binding protein 1; HDH-VIII

Protein Family

Ras GTPase-activating protein-binding protein

UniProt Gene Name

G3bp1

UniProt Synonym Gene Names

G3bp; G3BP-1

NCBI Protein Information

ras GTPase-activating protein-binding protein 1

UniProt Comments for G3bp1

May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.

Research Articles on G3bp1

1. the aberrant mutant SOD1-G3BP1 interaction affects stress granule dynamics

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with G3bp1 recombinant protein

Products by Pathway	Pathway Diagram
MRNA Processing Pathway antibodies	MRNA Processing Pathway Diagram

Diseases associated with G3bp1 recombinant protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>7 publications with G3bp1 and Neoplasms
Breast Neoplasms Antibodies	>4 publications with G3bp1 and Breast Neoplasms
Lung Neoplasms Antibodies	>2 publications with G3bp1 and Lung Neoplasms
Adenocarcinoma Antibodies	>2 publications with G3bp1 and Adenocarcinoma
Liver Diseases Antibodies	>1 publications with G3bp1 and Liver Diseases
Vascular Diseases Antibodies	>1 publications with G3bp1 and Vascular Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with G3bp1 and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>1 publications with G3bp1 and Liver Neoplasms

Organs/Tissues associated with G3bp1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Thymus Antibodies	>1 publications with G3bp1 and Thymus