Enhancer of Mrna Decapping Protein 1 (EDC1) ELISA Kit for Cavy

Name: Cavy EDC1 ELISA Kit; Enhancer of Mrna Decapping Protein 1; MyBioSource
Brand: MyBioSource
SKU: MBS095052
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS095052

MBS095052 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Enhancer of mRNA Decapping Protein 1 (EDC1) ELISA Kit target analytes in biological samples. The concentration gradients… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Enhancer of mRNA Decapping Protein 1 (EDC1), ELISA Kit

Full Product Name

Cavy Enhancer of mRNA Decapping Protein 1 ELISA Kit

Product Gene Name

EDC1 elisa kit

Species Reactivity

Cavy

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

151,661 Da

OMIM

606030

3D Structure

ModBase 3D Structure for Q6P2E9

Other Notes

Small volumes of EDC1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EDC1. It may not necessarily be applicable to this product.

NCBI GI #

74758241

NCBI GeneID

23644

NCBI Accession #

Q6P2E9.1

UniProt Primary Accession #

Q6P2E9

UniProt Secondary Accession #

Q13025; Q13826; Q6ZR12; Q7Z6H7; A6NGM1; A8K4T4

UniProt Related Accession #

Q6P2E9

NCBI Official Full Name

Enhancer of mRNA-decapping protein 4

NCBI Official Synonym Full Names

enhancer of mRNA decapping 4

NCBI Official Symbol

EDC4

NCBI Official Synonym Symbols

GE1; Ge-1; RCD8; HEDL5; HEDLS; RCD-8

UniProt Protein Name

Enhancer of mRNA-decapping protein 4

UniProt Synonym Protein Names

Autoantigen Ge-1; Autoantigen RCD-8; Human enhancer of decapping large subunit

Protein Family

Enhancer of mRNA-decapping protein

UniProt Gene Name

EDC4

UniProt Synonym Gene Names

HEDLS; Hedls

UniProt Entry Name

EDC4_HUMAN

NCBI Protein Information

enhancer of mRNA-decapping protein 4; autoantigen Ge-1; autoantigen RCD-8; human enhancer of decapping large subunit

UniProt Comments for EDC1

EDC4: a protein required for the 5' a?? 3' pathway of mRNA decapping and degradation-based post-transcriptional gene silencing. The proteins involved in 5' a?? 3' mRNA decay include DCP2, DCP1A, EDC3, EDC4 and DDX6, and are concentrated in cytoplasmic structures called mRNA "processing bodies" (P-bodies). Shortening of the 3'-poly(A) tail and removal of PABP precedes cleavage of the 5'-mRNA cap by a complex containing decapping enzymes 1A and 2 (DCP1A/DCP2). EDC4 enhances the catalytic activity of DCP2 in vitro. Shown to be required for silencing by miRNAs in Drosophila melanogaster. Two alternatively spliced human isoforms have been described.

Protein type: RNA processing

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; membrane; cytoplasm; nucleus; cytosol

Molecular Function: protein binding

Biological Process: gene expression; mRNA catabolic process, deadenylation-dependent decay

Research Articles on EDC1

1. The data indicates that DCP2 activation by DCP1 occurs preferentially on the EDC4 scaffold, which may serve to couple DCP2 activation by DCP1 with 5'-to-3' mRNA degradation by XRN1 in human cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EDC1 elisa kit

Reference Product	PubMed Publications
DCP2 elisa kit	>14 publications with EDC1 and DCP2
DCP1A elisa kit	>11 publications with EDC1 and DCP1A
XRN1 elisa kit	>8 publications with EDC1 and XRN1
EDC3 elisa kit	>6 publications with EDC1 and EDC3
DDX6 elisa kit	>6 publications with EDC1 and DDX6
LSM1 elisa kit	>5 publications with EDC1 and LSM1
PATL1 elisa kit	>2 publications with EDC1 and PATL1

Pathways associated with EDC1 elisa kit

Products by Pathway	Pathway Diagram
Deadenylation-dependent MRNA Decay Pathway antibodies	Deadenylation-dependent MRNA Decay Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
RNA Degradation Pathway antibodies	RNA Degradation Pathway Diagram
RNA Degradation Pathway antibodies	RNA Degradation Pathway Diagram
MRNA Decay By 5' To 3' Exoribonuclease Pathway antibodies	MRNA Decay By 5' To 3' Exoribonuclease Pathway Diagram

Diseases associated with EDC1 elisa kit

Disease Name	Pubmed Publications
Liver Diseases Antibodies	>4 publications with EDC1 and Liver Diseases
Cardiovascular Diseases Antibodies	>1 publications with EDC1 and Cardiovascular Diseases
Neoplasms Antibodies	>1 publications with EDC1 and Neoplasms
Carcinoma, Hepatocellular Antibodies	>1 publications with EDC1 and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>1 publications with EDC1 and Liver Neoplasms
Inflammation Antibodies	>1 publications with EDC1 and Inflammation

Organs/Tissues associated with EDC1 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>6 publications with EDC1 and Blood
Liver Antibodies	>4 publications with EDC1 and Liver
Muscle Antibodies	>3 publications with EDC1 and Muscle
Nerve Antibodies	>2 publications with EDC1 and Nerve
Kidney Antibodies	>1 publications with EDC1 and Kidney
Skin Antibodies	>1 publications with EDC1 and Skin