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Lactase-Phlorizin Hydrolase (LCT) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS950533

This protein belongs to the family 1 of glycosyl hydrolases. The protein is integral to plasma membrane and has both phlorizin hydrolase activity and lactase activity. More details

$340 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Lactase-phlorizin hydrolase (LCT), Recombinant Protein
Full Product Name
Recombinant Human Lactase-phlorizin hydrolase (LCT) , partial
Product Gene Name
Sequence
SDWESDRNFI STAGPLTNDL LHNLSGLLGD QSSNFVAGDK DMYVCHQPLP TFLPEYFSSL HASQITHYKV FLSWAQLLPA GSTQNPDEKT VQCYRRLLKA LKTARLQPMV ILHHQTLPAS TLRRTEAFAD LFADYATFAF HSFGDLVGIW FTFSDLEEVI KELPHQESRA SQLQTLSDAH RKAYEIYHES YAFQGGKLSV V
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
218,587 Da
Sequence Positions
20-220aa; partial
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
223000
3D Structure
ModBase 3D Structure for P09848
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of LCT recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LCT purchase

MBS950533 is a recombinant protein targeting LCT. Also known as Recombinant Human Lactase-phlorizin hydrolase (LCT) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for LCT. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lactase-phlorizin hydrolase preproprotein
NCBI Official Synonym Full Names
lactase
NCBI Official Symbol
LCT
NCBI Official Synonym Symbols
LAC; LPH; LPH1
UniProt Protein Name
Lactase-phlorizin hydrolase
UniProt Synonym Protein Names
Lactase-glycosylceramidaseIncluding the following 2 domains:Lactase (EC:3.2.1.108)Phlorizin hydrolase (EC:3.2.1.62)
UniProt Gene Name
LCT
UniProt Synonym Gene Names
LPH
NCBI Protein Information
lactase-phlorizin hydrolase

NCBI Summary for LCT

The protein encoded by this gene belongs to the glycosyl hydrolase 1 family of proteins. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme is integral to the plasma membrane and has both phlorizin hydrolase activity and lactase activity. Mutations in this gene are associated with congenital lactase deficiency. Polymorphisms in this gene are associated with lactase persistence, in which intestinal lactase activity persists at childhood levels into adulthood. [provided by RefSeq, Jan 2016]
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UniProt Comments for LCT

LPH splits lactose in the small intestine.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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