Collagen Alpha-1(xii) Chain (COL12A1) Gallus Gallus Recombinant Protein

Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix.

The complete primary structure of type XII collagen shows a chimeric molecule with reiterated fibronectin type III motifs, von Willebrand factor A motifs, a domain homologous to a noncollagenous region of type IX collagen, and short collagenous domains with an Arg-Gly-Asp site.Yamagata M., Yamada K.M., Yamada S.S., Shinomura T., Tanaka H., Nishida Y., Obara M., Kimata K.J. Cell Biol. 115:209-221(1991) Type XII collagen. A large multidomain molecule with partial homology to type IX collagen.Gordon M.K., Gerecke D.R., Dublet B., van der Rest M., Olsen B.R.J. Biol. Chem. 264:19772-19778(1989) Type XII collagen distinct extracellular matrix component discovered by cDNA cloning.Gordon M.K., Gerecke D.R., Olsen B.R.Proc. Natl. Acad. Sci. U.S.A. 84:6040-6044(1987) The two splice variants of collagen XII share a common 5' end.Trueb J., Trueb B.Biochim. Biophys. Acta 1171:97-98(1992) Large and small splice variants of collagen XII differential expression and ligand binding.Koch M., Bohrmann B., Matthison M., Hagios C., Trueb B., Chiquet M.J. Cell Biol. 130:1005-1014(1995)

Small volumes of COL12A1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS950982 is a recombinant protein targeting COL12A1. Also known as Recombinant Gallus gallus Collagen alpha-1(XII) chain. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.