Human NUP62 Recombinant Protein – Cat# MBS951100

Nuclear Pore Glycoprotein P62 (NUP62) Human Recombinant Protein

Name: NUP62 Recombinant Protein; Nuclear Pore Glycoprotein P62; Human; MyBioSource
Brand: MyBioSource
SKU: MBS951100
Price: 1325 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS951100

$1325 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Nuclear pore glycoprotein p62 (NUP62), Recombinant Protein

Full Product Name

Recombinant Human Nuclear pore glycoprotein p62 (NUP62)

Product Gene Name

NUP62 recombinant protein

Sequence

SGFNFGGTGA PTGGFTFGTA KTATTTPATG FSFSTSGTGG FNFGAPFQPA TSTPSTGLFS LATQTPATQT TGFTFGTATL ASGGTGFSLG IGASKLNLSN TAATPAMANP SGFGLGSSNL TNAISSTVTS SQGTAPTGFV FGPSTTSVAP ATTSGGFSFT GGSTAQPSGF NIGSAGNSAQ PTAPATLPFT PATPAATTAG ATQPAAPTPT ATITSTGPSL FASIATAPTS SATTGLSLCT PVTTAGAPTA GTQGFSLKAP GAASGTSTTT STAATATATT TSSSSTTGFA LNLKPLAPAG IPSNTAAAVT APPGPGAAAG AAASSAMTYA QLESLINKWS LELEDQERHF LQQATQVNAW DRTLIENGEK ITSLHREVEK VKLDQKRLDQ ELDFILSQQK ELEDLLSPLE ELVKEQSGTI YLQHADEERE KTYKLAENID AQLKRMAQDL KDIIEHLNTS GAPADTSDPL QQICKILNAH MDSLQWIDQN SALLQRKVEE VTKVCEGRRK EQERSFRITF D

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

53,255 Da

Sequence Positions

2-522, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

271930

3D Structure

ModBase 3D Structure for P37198

Species

Human

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NUP62 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NUP62 purchase

MBS951100 is a recombinant protein targeting NUP62. Also known as Recombinant Human Nuclear pore glycoprotein p62 (NUP62). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for NUP62. It may not necessarily be applicable to this product.

NCBI GI #

301069416

NCBI GeneID

23636

NCBI Accession #

NP_001180286.1

UniProt Primary Accession #

P37198

UniProt Secondary Accession #

Q503A4; Q6GTM2; Q96C43; Q9NSL1; B3KWU5

UniProt Related Accession #

P37198

GenBank Nucleotide #

NM_001193357.1

NCBI Official Full Name

nuclear pore glycoprotein p62

NCBI Official Synonym Full Names

nucleoporin 62

NCBI Official Symbol

NUP62

NCBI Official Synonym Symbols

p62; IBSN; SNDI

UniProt Protein Name

Nuclear pore glycoprotein p62

UniProt Synonym Protein Names

62 kDa nucleoporin; Nucleoporin Nup62

Protein Family

Nuclear pore complex protein

UniProt Gene Name

NUP62

NCBI Protein Information

nuclear pore glycoprotein p62

NCBI Summary for NUP62

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform. [provided by RefSeq, Jul 2008]

UniProt Comments for NUP62

Essential component of the nuclear pore complex (PubMed:1915414). The N-terminal is probably involved in nucleocytoplasmic transport (PubMed:1915414). The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex (PubMed:1915414, PubMed:24107630). Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation (PubMed:24107630). It might be involved in protein recruitment to the centrosome after nuclear breakdown (PubMed:24107630).

Research Articles on NUP62

1. it was revealed that a fraction of Nup62 was associated with mitotic spindle microtubule instead of spindle matrix, and the localization of Nup62 in the mitotic spindle depended on its three coiled-coil domains rather than Crm1, although Nup62 strongly interacted with Crm1 during mitosis. Moreover, depletion of Nup62 by small interference of RNA seriously induced the defects of chromosome alignment and spindle assembly

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NUP62 recombinant protein

Reference Product	PubMed Publications
NUP153 recombinant protein	>21 publications with NUP62 and NUP153
NUP214 recombinant protein	>11 publications with NUP62 and NUP214
NUP54 recombinant protein	>3 publications with NUP62 and NUP54
NUP93 recombinant protein	>3 publications with NUP62 and NUP93
NXF1 recombinant protein	>3 publications with NUP62 and NXF1
KPNB1 recombinant protein	>2 publications with NUP62 and KPNB1
NUP50 recombinant protein	>1 publications with NUP62 and NUP50

Pathways associated with NUP62 recombinant protein

Products by Pathway	Pathway Diagram
Antiviral Mechanism By IFN-stimulated Genes Pathway antibodies	Antiviral Mechanism By IFN-stimulated Genes Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Export Of Viral Ribonucleoproteins From Nucleus Pathway antibodies	Export Of Viral Ribonucleoproteins From Nucleus Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Glucose Transport Pathway antibodies	Glucose Transport Pathway Diagram
Glycogen Storage Diseases Pathway antibodies	Glycogen Storage Diseases Pathway Diagram
HIV Infection Pathway antibodies	HIV Infection Pathway Diagram

Diseases associated with NUP62 recombinant protein

Disease Name	Pubmed Publications
Carcinoma Antibodies	>2 publications with NUP62 and Carcinoma
Liver Diseases Antibodies	>1 publications with NUP62 and Liver Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with NUP62 and Carcinoma, Hepatocellular
Disease Models, Animal Antibodies	>1 publications with NUP62 and Disease Models, Animal
Inflammation Antibodies	>1 publications with NUP62 and Inflammation
Kidney Diseases Antibodies	>1 publications with NUP62 and Kidney Diseases
Weight Loss Antibodies	>1 publications with NUP62 and Weight Loss
Necrosis Antibodies	>1 publications with NUP62 and Necrosis

Organs/Tissues associated with NUP62 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>6 publications with NUP62 and Brain
Blood Antibodies	>4 publications with NUP62 and Blood
Kidney Antibodies	>4 publications with NUP62 and Kidney
Testis Antibodies	>4 publications with NUP62 and Testis
Liver Antibodies	>3 publications with NUP62 and Liver
Vascular Antibodies	>2 publications with NUP62 and Vascular
Lymph Antibodies	>1 publications with NUP62 and Lymph
Heart Antibodies	>1 publications with NUP62 and Heart
Mouth Antibodies	>1 publications with NUP62 and Mouth
Intestine Antibodies	>1 publications with NUP62 and Intestine