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Chromogranin-A (CHGA) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS952698

This protein is a member of the chromograninsecretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin,… More details

$1215 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Chromogranin-A (Chga), Recombinant Protein
Full Product Name
Recombinant Mouse Chromogranin-A (Chga)
Product Gene Name
Sequence
LPVNSPMTKG DTKVMKCVLE VISDSLSKPS PMPVSPECLE TLQGDERILS ILRHQNLLKE LQDLALQGAK ERAQQPLKQQ QPPKQQQQQQ QQQQQEQQHS SFEDELSEVF ENQSPDAKHR DAAAEVPSRD TMEKRKDSDK GQQDGFEATT EGPRPQAFPE PNQESPMMGD SESPGEDTAT NTQSPTSLPS QEHVDPQATG DSERGLSAQQ QARKAKQEEK EEEEEEEAVA REKAGPEEVP TAASSSHFHA GYKAIQKDDG QSDSQAVDGD GKTEASEALP SEGKGELEHS QQEEDGEEAM VGTPQGLFPQ GGKGRELEHK QEEEEEEEER LSREWEDKRW SRMDQLAKEL TAEKRLEGED DPDRSMKLSF RTRAYGFRDP GPQLRRGWRP SSREDSVEAR SDFEEKKEEE GSANRRAEDQ ELESLSAIEA ELEKVAHQLQ ALRRG
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
51,789 Da
Sequence Positions
19-463, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P26339
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Chga recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Chga purchase

MBS952698 is a recombinant protein targeting Chga. Also known as Recombinant Mouse Chromogranin-A (Chga). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Chga. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
chromogranin-A preproprotein
NCBI Official Synonym Full Names
chromogranin A
NCBI Official Symbol
Chga
NCBI Official Synonym Symbols
cgA; ChrA
UniProt Protein Name
Chromogranin-A
UniProt Synonym Protein Names
AL26
Protein Family
UniProt Gene Name
Chga
UniProt Synonym Gene Names
CgA
NCBI Protein Information
chromogranin-A

NCBI Summary for Chga

This gene encodes a member of the granin family of acidic secretory glycoproteins that are expressed in endocrine cells and neurons. The encoded preproprotein undergoes proteolytic processing to generate multiple functions peptides including pancreastatin, catestatin and serpinin. The encoded protein plays important roles in the neuroendocrine system including regulated secretion of peptide hormones and neurotransmitters. Mice lacking the encoded protein exhibit elevated blood pressure which can be rescued by transgenic expression of the human ortholog. [provided by RefSeq, Nov 2015]
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UniProt Comments for Chga

Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas.Catestatin: Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist. Can induce mast cell migration, degranulation and production of cytokines and chemokines.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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