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ATP-Binding Cassette Sub-Family E Member 1 (ABCE1) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS952782

This protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDRTAP, MRP, ALD, OABP,… More details

$1395 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ATP-binding cassette sub-family E member 1 (Abce1), Recombinant Protein
Full Product Name
Recombinant Mouse ATP-binding cassette sub-family E member 1 (Abce1)
Product Gene Name
Abce1 recombinant protein
Sequence
MADKLTRIAI VNHDKCKPKK CRQECKKSCP VVRMGKLCIE VTPQSKIAWI SETLCIGCGI CIKKCPFGAL SIVNLPSNLE KETTHRYCAN AFKLHRLPIP RPGEVLGLVG TNGIGKSTAL KILAGKQKPN LGKYDDPPDW QEILTYFRGS ELQNYFTKIL EDDLKAIIKP QYVDQIPKAA KGTVGSILDR KDETKTQAIV CQQLDLTHLK ERNVEDLSGG ELQRFACAVV CIQKADIFMF DEPSSYLDVK QRLKAAITIR SLINPDRYII VVEHDLSVLD YLSDFICCLY GVPSAYGVVT MPFSVREGIN IFLDGYVPTE NLRFRDASLV FKVAETANEE EVKKMCMYKY PGMKKKMGEF ELAIVAGEFT DSEIMVMLGE NGTGKTTFIR MLAGRLKPDE GGEVPVLNVS YKPQKISPKS TGSVRQLLHE KIRDAYTHPQ FVTDVMKPLQ IENIIDQEVQ TLSGGELQRV ALALCLGKPA DVYLIDEPSA YLDSEQRLMA ARVVKRFILH AKKTAFVVEH DFIMATYLAD RVIVFDGVPS KNTVANSPQT LLAGMNKFLS QLEITFRRDP NNYRPRINKL NSIKDVEQKK SGNYFFLDD
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
67,314 Da
Sequence Positions
1-599, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P61222
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Abce1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Abce1 purchase

MBS952782 is a recombinant protein targeting Abce1. Also known as Recombinant Mouse ATP-binding cassette sub-family E member 1 (Abce1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Abce1. It may not necessarily be applicable to this product.

NCBI GI #
114205431
NCBI GeneID
24015
NCBI Accession #
NP_056566.2
UniProt Primary Accession #
P61222
UniProt Secondary Accession #
O88793; Q13181; Q13864; Q96AL0; Q96B10; Q99K66
UniProt Related Accession #
P61222
GenBank Nucleotide #
NM_015751.2
NCBI Official Full Name
ATP-binding cassette sub-family E member 1
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family E (OABP), member 1
NCBI Official Symbol
Abce1
NCBI Official Synonym Symbols
RLI; Oabp; RNS41; RNS4I; C79080; Rnaseli
UniProt Protein Name
ATP-binding cassette sub-family E member 1
UniProt Synonym Protein Names
RNase L inhibitor; Ribonuclease 4 inhibitor; RNS4I
Protein Family
ABC transporter E family
UniProt Gene Name
Abce1
UniProt Synonym Gene Names
Rli; RNS4I
NCBI Protein Information
ATP-binding cassette sub-family E member 1

NCBI Summary for Abce1

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. [provided by RefSeq, Jul 2008]
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UniProt Comments for Abce1

Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway ().
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Research Articles on Abce1

1. Expression of RNase L is a signal generated by NMDA receptor in cortical neurons. RNase L expression and RNA degradation may be events that cause neuronal damage induced by NMDA receptor activation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with Abce1 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >3 publications with Abce1 and Neoplasm Metastasis
 Liver Diseases Antibodies  >3 publications with Abce1 and Liver Diseases
 Prostatic Diseases Antibodies  >2 publications with Abce1 and Prostatic Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with Abce1 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >2 publications with Abce1 and Liver Neoplasms
 Liver Failure Antibodies  >1 publications with Abce1 and Liver Failure
 Drug Toxicity Antibodies  >1 publications with Abce1 and Drug Toxicity
 Atrophy Antibodies  >1 publications with Abce1 and Atrophy

Organs/Tissues associated with Abce1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with Abce1 and Blood
 Lung Antibodies  >4 publications with Abce1 and Lung
 Liver Antibodies  >3 publications with Abce1 and Liver
 Skin Antibodies  >2 publications with Abce1 and Skin
 Intestine Antibodies  >1 publications with Abce1 and Intestine
 Bone Antibodies  >1 publications with Abce1 and Bone
 Bone Marrow Antibodies  >1 publications with Abce1 and Bone Marrow
 Testis Antibodies  >1 publications with Abce1 and Testis
 Brain Antibodies  >1 publications with Abce1 and Brain
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