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Aquaporin-1 (AQP1) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS953294

MBS953294 is a recombinant protein targeting Aqp1. Also known as Recombinant Rat Aquaporin-1 (Aqp1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Aquaporin-1 (Aqp1), Recombinant Protein
Full Product Name
Recombinant Rat Aquaporin-1 (Aqp1)
Product Gene Name
Aqp1 recombinant protein
Product Synonym Gene Name
Aqp1; Chip28
Product Synonym Names
Recombinant Aquaporin-1 (Aqp1); Aquaporin-1; AQP-1; Aquaporin-CHIP Water channel protein for red blood cells and kidney proximal tubule
Sequence
ASEIKKKLFW RAVVAEFLAM TLFVFISIGS ALGFNYPLER NQTLVQDNVK VSLAFGLSIA TLAQSVGHIS GAHLNPAVTL GLLLSCQISI LRAVMYIIAQ CVGAIVASAI LSGITSSLLE NSLGRNDLAR GVNSGQGLGI EIIGTLQLVL CVLATTDRRR RDLGGSAPLA IGLSVALGHL LAIDYTGCGI NPARSFGSAV LTRNFSNHWI FWVGPFIGSA LAVLIYDFIL APRSSDFTDR MKVWTSGQVE EYDLDADDIN SRVEMKPK
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
28,857 Da
Sequence Positions
2-269
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 4; NC_005103.3 (150203461..150215641). Location: 4q24
3D Structure
ModBase 3D Structure for P29975
Species
Rattus norvegicus (Rat)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Aqp1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Aqp1. It may not necessarily be applicable to this product.

NCBI GI #
6978527
NCBI GeneID
25240
NCBI Accession #
NP_036910.1
UniProt Primary Accession #
P29975
UniProt Secondary Accession #
Q5EB50; Q7TN36
UniProt Related Accession #
P29975
GenBank Nucleotide #
NM_012778.1
NCBI Official Full Name
aquaporin-1
NCBI Official Synonym Full Names
aquaporin 1
NCBI Official Symbol
Aqp1
NCBI Official Synonym Symbols
CHIP28
UniProt Protein Name
Aquaporin-1
UniProt Synonym Protein Names
Aquaporin-CHIP; Water channel protein for red blood cells and kidney proximal tubule
UniProt Gene Name
Aqp1
UniProt Synonym Gene Names
Chip28; AQP-1
UniProt Entry Name
AQP1_RAT
NCBI Protein Information
aquaporin-1; AQP-1; aquaporin-CHIP; Aquaporin 1 (aquaporin channel forming integral protein 28 (CHIP)); water channel protein for red blood cells and kidney proximal tubule

NCBI Summary for Aqp1

integral membrane protein that is a major water transport molecule in the kidney proximal tubule and red blood cells [RGD, Feb 2006]

UniProt Comments for Aqp1

AQP1: Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Belongs to the MIP/aquaporin (TC 1.A.8) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, aquaporin family

Cellular Component: neuron projection; nuclear membrane; cell; brush border membrane; basolateral plasma membrane; integral to plasma membrane; integral to membrane; membrane; apical part of cell; axon; apical plasma membrane; cytoplasm; plasma membrane; basal plasma membrane; nerve terminal; nucleus; brush border; sarcolemma

Molecular Function: protein binding; ephrin receptor binding; potassium channel activity; water transporter activity; ammonium transmembrane transporter activity; intracellular cGMP activated cation channel activity; potassium ion transmembrane transporter activity; glycerol transmembrane transporter activity; transmembrane transporter activity; water channel activity; nitric oxide transporter activity; glycerol channel activity

Biological Process: glycerol transport; cGMP biosynthetic process; cerebrospinal fluid secretion; wound healing; water transport; carbon dioxide transport; response to hormone stimulus; negative regulation of caspase activity; sensory perception of pain; pancreatic juice secretion; positive regulation of saliva secretion; water homeostasis; odontogenesis; positive regulation of fibroblast proliferation; nitric oxide transport; hyperosmotic salinity response; multicellular organismal water homeostasis; cellular homeostasis; potassium ion transport; lipid digestion; lateral ventricle development; secretion by cell; response to drug; cellular water homeostasis; secretory granule organization and biogenesis; glomerular filtration; ammonium transport; positive regulation of angiogenesis; renal water transport; hyperosmotic response; camera-type eye morphogenesis; response to estrogen stimulus; adrenocorticotropin hormone secretion; establishment and/or maintenance of actin cytoskeleton polarity; cell volume homeostasis; negative regulation of apoptosis; positive regulation of cell migration
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Research Articles on Aqp1

1. Although water deprivation did not significantly change AQP1 levels in the mesenteric arteries, AQP1 protein concentrations were inversely correlated with the ratio of the VACM-1 to Nedd8-modified VACM-1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Aqp1 recombinant protein

 Products by Pathway  Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 O2/CO2 Exchange In Erythrocytes Pathway antibodies  O2/CO2 Exchange In Erythrocytes Pathway Diagram
 Passive Transport By Aquaporins Pathway antibodies  Passive Transport By Aquaporins Pathway Diagram
 Proximal Tubule Bicarbonate Reclamation Pathway antibodies  Proximal Tubule Bicarbonate Reclamation Pathway Diagram
 Proximal Tubule Bicarbonate Reclamation Pathway antibodies  Proximal Tubule Bicarbonate Reclamation Pathway Diagram
 Regulation Of Water Balance By Renal Aquaporins Pathway antibodies  Regulation Of Water Balance By Renal Aquaporins Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram

Diseases associated with Aqp1 recombinant protein

 Disease Name  Pubmed Publications
 Edema Antibodies  >117 publications with Aqp1 and Edema
 Kidney Diseases Antibodies  >104 publications with Aqp1 and Kidney Diseases
 Neoplasms Antibodies  >74 publications with Aqp1 and Neoplasms
 Nervous System Diseases Antibodies  >73 publications with Aqp1 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >49 publications with Aqp1 and Cardiovascular Diseases
 Vascular Diseases Antibodies  >44 publications with Aqp1 and Vascular Diseases
 Lung Diseases Antibodies  >41 publications with Aqp1 and Lung Diseases
 Carcinoma Antibodies  >37 publications with Aqp1 and Carcinoma
 Lung Injury Antibodies  >29 publications with Aqp1 and Lung Injury
 Fibrosis Antibodies  >25 publications with Aqp1 and Fibrosis

Organs/Tissues associated with Aqp1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >349 publications with Aqp1 and Kidney
 Brain Antibodies  >168 publications with Aqp1 and Brain
 Eye Antibodies  >123 publications with Aqp1 and Eye
 Lung Antibodies  >119 publications with Aqp1 and Lung
 Heart Antibodies  >43 publications with Aqp1 and Heart
 Embryonic Tissue Antibodies  >31 publications with Aqp1 and Embryonic Tissue
 Artery Antibodies  >30 publications with Aqp1 and Artery
 Placenta Antibodies  >17 publications with Aqp1 and Placenta
 Ovary Antibodies  >14 publications with Aqp1 and Ovary
 Connective Tissue Antibodies  >13 publications with Aqp1 and Connective Tissue
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