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Neuropeptide Y Receptor Type 1 (NPY1R) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS953305

MBS953305 is a recombinant protein targeting Npy1r. Also known as Recombinant Rat Neuropeptide Y receptor type 1 (Npy1r). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Neuropeptide Y receptor type 1 (Npy1r), Recombinant Protein
Full Product Name
Recombinant Rat Neuropeptide Y receptor type 1 (Npy1r)
Product Gene Name
Npy1r recombinant protein
Product Synonym Gene Name
Npy1r
Product Synonym Names
Recombinant Neuropeptide Y receptor type 1 (Npy1r); Neuropeptide Y receptor type 1; NPY1-R; FC5
Sequence
MNSTLFSRVE NYSVHYNVSE NSPFLAFEND DCHLPLAVIF TLALAYGAVI ILGVSGNLAL IIIILKQKEM RNVTNILIVN LSFSDLLVAV MCLPFTFVYT LMDHWVFGET MCKLNPFVQC VSITVSIFSL VLIAVERHQL IINPRGWRPN NRHAYIGITV IWVLAVASSL PFVIYQILTD EPFQNVSLAA FKDKYVCFDK FPSDSHRLSY TTLLLVLQYF GPLCFIFICY FKIYIRLKRR NNMMDKIRDS KYRSSETKRI NVMLLSIVVA FAVCWLPLTI FNTVFDWNHQ IIATCNHNLL FLLCHLTAMI STCVNPIFYG FLNKNFQRDL QFFFNFCDFR SRDDDYETIA MSTMHTDVSK TSLKQASPVA FKKISMNDNE KI
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
44,117 Da
Sequence Positions
1-382
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 16; NC_005115.3 (24663045..24671859, complement). Location: 16p14
3D Structure
ModBase 3D Structure for P21555
Species
Rattus norvegicus (Rat)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Npy1r recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Npy1r. It may not necessarily be applicable to this product.

NCBI GI #
128998
NCBI GeneID
29358
NCBI Accession #
P21555.3
UniProt Primary Accession #
P21555
UniProt Related Accession #
P21555
NCBI Official Full Name
Neuropeptide Y receptor type 1
NCBI Official Synonym Full Names
neuropeptide Y receptor Y1
NCBI Official Symbol
Npy1r
NCBI Official Synonym Symbols
NPY-1
UniProt Protein Name
Neuropeptide Y receptor type 1
UniProt Synonym Protein Names
FC5
Protein Family
Neuropeptide Y receptor
UniProt Gene Name
Npy1r
UniProt Synonym Gene Names
NPY1-R
UniProt Entry Name
NPY1R_RAT
NCBI Protein Information
neuropeptide Y receptor type 1; FC5; NPY1-R; neuropeptide Y1 receptor; Neuropepetide Y1 Receptor

NCBI Summary for Npy1r

G protein-coupled receptor for neuropeptide Y and peptide YY [RGD, Feb 2006]

UniProt Comments for Npy1r

NPY1R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR

Cellular Component: synaptic vesicle; axon; integral to membrane; plasma membrane; cytosol

Molecular Function: peptide YY receptor activity; pancreatic polypeptide receptor activity; neuropeptide Y receptor activity

Biological Process: peristalsis; negative regulation of hormone secretion; glucose metabolic process; regulation of multicellular organism growth; locomotory behavior; sensory perception of pain; response to estradiol stimulus; synaptic transmission; neuropeptide signaling pathway; reduction of cytosolic calcium ion concentration; regulation of blood pressure; positive regulation of vasoconstriction; feeding behavior
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Research Articles on Npy1r

1. investigation of regulation of expression of NPY and NPY-Y1 receptor in neurons of the amygdala in mechanism of, conditioned resistance to, treatment of, and recovery from post-traumatic stress disorder

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Npy1r recombinant protein

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Peptide GPCRs Pathway antibodies  Peptide GPCRs Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Organs/Tissues associated with Npy1r recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >27 publications with Npy1r and Brain
 Dorsal Root Ganglion Antibodies  >2 publications with Npy1r and Dorsal Root Ganglion
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