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Calnexin (CANX) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS953595

MBS953595 is a recombinant protein targeting Canx. Also known as Recombinant Rat Calnexin (Canx). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. Canx More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Calnexin (Canx), Recombinant Protein
Full Product Name
Recombinant Rat Calnexin (Canx)
Product Gene Name
Canx recombinant protein
Product Synonym Names
Calnexin
Sequence
CSGKKQS NAMEYKKTDA PQPDVKDEEG KEEEKNKGDE EEEEEKLEEK QKSDAEEDGG TGSQDEEDSK PKAEEDEILN RSPRNRKPRR E
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
67,255 Da
Sequence Positions
504-591
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P35565
Species
Rattus norvegicus (Rat)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Canx recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Canx. It may not necessarily be applicable to this product.

NCBI GI #
25282419
NCBI GeneID
29144
NCBI Accession #
NP_742005.1
UniProt Primary Accession #
P35565
UniProt Related Accession #
P35565
GenBank Nucleotide #
NM_172008.2
NCBI Official Full Name
calnexin
NCBI Official Synonym Full Names
calnexin
NCBI Official Symbol
Canx
UniProt Protein Name
Calnexin
UniProt Gene Name
Canx
UniProt Entry Name
CALX_RAT
NCBI Protein Information
calnexin

NCBI Summary for Canx

calcium-binding protein that may serve to chaperone proteins from the ER to outer cellular membrane [RGD, Feb 2006]

UniProt Comments for Canx

Calnexin: a calcium-binding protein of the calreticulin family. A type I membrane protein of the endoplasmic reticulum .Interacts with newly synthesized glycoproteins in the endoplasmic reticulum. May act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.

Protein type: Calcium-binding; Membrane protein, integral; Endoplasmic reticulum; Motility/polarity/chemotaxis

Cellular Component: dendrite cytoplasm; endoplasmic reticulum membrane; protein complex; smooth endoplasmic reticulum; rough endoplasmic reticulum; cell; endoplasmic reticulum; dendritic spine; integral to membrane; cell soma; membrane; axon; cytoplasm; melanosome; ribosome; myelin sheath

Molecular Function: ionotropic glutamate receptor binding; protein binding; unfolded protein binding; apolipoprotein binding; calcium ion binding; carbohydrate binding; glycoprotein binding

Biological Process: synaptic vesicle endocytosis; aging
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Research Articles on Canx

1. calnexin localizes to the neuronal cell membrane & this recruitment is regulated in an NMDA receptor-dependent manner. immunoisolation of vesicles revealed co-localization of GluA2 and calnexin in post-ER intracellular membrane components.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Canx recombinant protein

 Reference Product  PubMed Publications
 Calr recombinant protein  >2 publications with Canx and Calr
 Pdia3 recombinant protein  >1 publications with Canx and Pdia3

Pathways associated with Canx recombinant protein

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway antibodies  Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 Calnexin/calreticulin Cycle Pathway antibodies  Calnexin/calreticulin Cycle Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram

Diseases associated with Canx recombinant protein

 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >2 publications with Canx and Adenocarcinoma
 Gastrointestinal Diseases Antibodies  >1 publications with Canx and Gastrointestinal Diseases
 Nervous System Diseases Antibodies  >1 publications with Canx and Nervous System Diseases
 Lung Diseases Antibodies  >1 publications with Canx and Lung Diseases
 Liver Diseases Antibodies  >1 publications with Canx and Liver Diseases
 Heart Diseases Antibodies  >1 publications with Canx and Heart Diseases

Organs/Tissues associated with Canx recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >2 publications with Canx and Testis
 Liver Antibodies  >2 publications with Canx and Liver
 Lung Antibodies  >2 publications with Canx and Lung
 Kidney Antibodies  >1 publications with Canx and Kidney
 Heart Antibodies  >1 publications with Canx and Heart
 Embryonic Tissue Antibodies  >1 publications with Canx and Embryonic Tissue
 Brain Antibodies  >1 publications with Canx and Brain
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