Human RAE1 Recombinant Protein – Cat# MBS953684

Mrna Export Factor (RAE1) Human Recombinant Protein

Name: RAE1 Recombinant Protein; Mrna Export Factor; Human; MyBioSource
Brand: MyBioSource
SKU: MBS953684
Price: 700 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS953684

Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. More details

$700 / 0.02 mg (Mammalian-Cell) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

mRNA export factor (RAE1), Recombinant Protein

Full Product Name

Recombinant Human mRNA export factor (RAE1)

Product Gene Name

RAE1 recombinant protein

Product Synonym Gene Name

RAE1; MRNP41

Product Synonym Names

mRNA export factor; Rae1 protein homolog; mRNA-associated protein mrnp 41

Sequence

MSLFGTTSGF GTSGTSMFGS ATTDNHNPMK DIEVTSSPDD SIGCLSFSPP TLPGNFLIAG SWANDVRCWE VQDSGQTIPK AQQMHTGPVL DVCWSDDGSK VFTASCDKTA KMWDLSSNQA IQIAQHDAPV KTIHWIKAPN YSCVMTGSWD KTLKFWDTRS SNPMMVLQLP ERCYCADVIY PMAVVATAER GLIVYQLENQ PSEFRRIESP LKHQHRCVAI FKDKQNKPTG FALGSIEGRV AIHYINPPNP AKDNFTFKCH RSNGTNTSAP QDIYAVNGIA FHPVHGTLAT VGSDGRFSFW DKDARTKLKT SEQLDQPISA CCFNHNGNIF AYASSYDWSK GHEFYNPQKK NYIFLRNAAE ELKPRNKK

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

68 kDa

Sequence Positions

1-368aa; Full Length

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

603343

3D Structure

ModBase 3D Structure for P78406

Species

Homo sapiens (Human)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of RAE1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAE1 purchase

MBS953684 is a recombinant protein targeting RAE1. Also known as Recombinant Human mRNA export factor (RAE1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for RAE1. It may not necessarily be applicable to this product.

NCBI GI #

62739173

NCBI GeneID

8480

NCBI Accession #

NP_001015885.1

UniProt Primary Accession #

P78406

UniProt Secondary Accession #

O15306; Q3SYL7; Q5TCH8; Q6V708; Q9H100; Q9NQM6; A8K882

UniProt Related Accession #

P78406

GenBank Nucleotide #

NM_001015885.1

NCBI Official Full Name

mRNA export factor

NCBI Official Synonym Full Names

ribonucleic acid export 1

NCBI Official Symbol

RAE1

NCBI Official Synonym Symbols

MIG14; MRNP41; Mnrp41; dJ481F12.3; dJ800J21.1

UniProt Protein Name

mRNA export factor

UniProt Synonym Protein Names

Rae1 protein homolog; mRNA-associated protein mrnp 41

Protein Family

Poly(A)+ RNA export protein

UniProt Gene Name

RAE1

UniProt Synonym Gene Names

MRNP41

UniProt Entry Name

RAE1L_HUMAN

NCBI Protein Information

mRNA export factor; mRNA export protein; rae1 protein homolog; RAE1 RNA export 1 homolog; migration-inducing gene 14; mRNA-binding protein, 41-kD; mRNA-associated protein MRNP 41; homolog of yeast Rae1 (Bharathi) mRNA-associated protein of 41 kDa (Kraemer)

NCBI Summary for RAE1

Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for RAE1

RAE1: Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Belongs to the WD repeat rae1 family.

Protein type: RNA-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 20q13.31

Cellular Component: nuclear outer membrane; cytoskeleton; cytoplasm; nucleolus; nuclear pore; nuclear envelope; nucleus

Molecular Function: RNA binding; microtubule binding

Biological Process: mRNA export from nucleus; viral reproduction; hexose transport; cytokine and chemokine mediated signaling pathway; carbohydrate metabolic process; mitotic nuclear envelope disassembly; viral transcription; gene expression; pathogenesis; glucose transport; mitotic cell cycle; viral infectious cycle; transmembrane transport

Research Articles on RAE1

1. Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair (Rae1 * Nup98).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RAE1 recombinant protein

Reference Product	PubMed Publications
NUP98 recombinant protein	>22 publications with RAE1 and NUP98
NXF1 recombinant protein	>5 publications with RAE1 and NXF1
BUB1 recombinant protein	>5 publications with RAE1 and BUB1

Pathways associated with RAE1 recombinant protein

Products by Pathway	Pathway Diagram
Antiviral Mechanism By IFN-stimulated Genes Pathway antibodies	Antiviral Mechanism By IFN-stimulated Genes Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Export Of Viral Ribonucleoproteins From Nucleus Pathway antibodies	Export Of Viral Ribonucleoproteins From Nucleus Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Glucose Transport Pathway antibodies	Glucose Transport Pathway Diagram
HIV Infection Pathway antibodies	HIV Infection Pathway Diagram
HIV Life Cycle Pathway antibodies	HIV Life Cycle Pathway Diagram
Hexose Transport Pathway antibodies	Hexose Transport Pathway Diagram
Host Interactions Of HIV Factors Pathway antibodies	Host Interactions Of HIV Factors Pathway Diagram

Diseases associated with RAE1 recombinant protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>24 publications with RAE1 and Neoplasms
Chromosome Aberrations Antibodies	>10 publications with RAE1 and Chromosome Aberrations
Cell Transformation, Neoplastic Antibodies	>6 publications with RAE1 and Cell Transformation, Neoplastic
Disease Models, Animal Antibodies	>6 publications with RAE1 and Disease Models, Animal
Inflammation Antibodies	>3 publications with RAE1 and Inflammation
Liver Diseases Antibodies	>3 publications with RAE1 and Liver Diseases
Necrosis Antibodies	>3 publications with RAE1 and Necrosis
Kidney Diseases Antibodies	>2 publications with RAE1 and Kidney Diseases
Prostatic Diseases Antibodies	>2 publications with RAE1 and Prostatic Diseases
Drug-Induced Liver Injury Antibodies	>2 publications with RAE1 and Drug-Induced Liver Injury

Organs/Tissues associated with RAE1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>28 publications with RAE1 and Blood
Liver Antibodies	>6 publications with RAE1 and Liver
Brain Antibodies	>5 publications with RAE1 and Brain
Lung Antibodies	>3 publications with RAE1 and Lung
Bone Antibodies	>3 publications with RAE1 and Bone
Bone Marrow Antibodies	>3 publications with RAE1 and Bone Marrow
Lymph Node Antibodies	>2 publications with RAE1 and Lymph Node
Pancreas Antibodies	>2 publications with RAE1 and Pancreas
Kidney Antibodies	>2 publications with RAE1 and Kidney
Salivary Gland Antibodies	>2 publications with RAE1 and Salivary Gland