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Meckelin (TMEM67) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS953830

MBS953830 is a recombinant protein targeting Tmem67. Also known as Recombinant Rat Meckelin (Tmem67) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$4200 / 1 mg (E-Coli) +5 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Meckelin (Tmem67), Recombinant Protein
Full Product Name
Recombinant Rat Meckelin (Tmem67) , partial
Product Gene Name
Tmem67 recombinant protein
Sequence
MVMRTRPLAA MAVRSCFSAL TGTVYLLLVL CEVSWAQIFS FPFQRPETCD LNQYFDISAL SCAPCGANQR RDALGTSCIC LPGYHMISNN GGPSIICKKC PENMKGVTKD GWDCISCPNG LTAEGKCHCP SGHILVERNV SGSLLSQATC ELCDGNENSF TKPNALGTRC VRCEPTFVNT SRSCSCSEPH ISTGGLCFSN TGNFPQRLIS TERYGELGMS SNSEWFTKYL QATAAACWTH SNLTSCQALG NMCVMNMNSY DSTTFDACRL FHYVFEGAAG LTGVHSVPFW RQNLPWLFYG DQPGLASQVL STTPLPTNFS FKGQNQLKFV AASYDIRGNF IRWQTVKGGV LQLCPDTERR LDAAYSFGTT YQQNCEISLS KLLADFPSPV FYDIYLEYTD EVQHHYLWAI PVLNLNLQHN KLFVNQDSSS SKWLLTRRIF LVDAVSGREN DLGNQPRVIR VATQISLSIR LVPNTKNGNI YTPLLTIAYS DIDIKNAYSQ SVKISFSVKY EMNQGDAFVQ TDIALGVLGG LAVLSSLLKT AGWKRRIGSP MIDLQTVMKF LLYYAGDLAN VFFIITVGTG LYWLIFFKAQ KSVSVLLPMP VQEERFVTYV GCAFAMKALQ FLHKLISQIT IDIFFIDWER PKGKVLKAVE GEGGVRSATV PVSIWRTYFV ANEWNEIQTV RKINPLFQVL TTLFFLEVVG FKNLALMDPS SSLSRSLSDY AAPYSRILRY AVATTIWLVI GIVQVVFFAA FYERFIEDKI RQFVDLCSMS NVSVFLLSHR CFGYYIHGRS VHGHADTNME DMNMNLRREA ENLCSQRGLV PNTDGQTFQI AVSSQMRQHY DRIHETLTRR NGPARLLSSS GSTLEQSIKA YHAMNKFLGS FIDHVHKEMD YFIKDKLLLE KILGMEFMEP LEKSIFYNDE SHSFSSVLYY GNEATLLIFD LLFFCVVDLA CQNFVLASFL TYLQQEIFRF IRNTVGQKNL ATKTLVDERF LI
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
111,740 Da
Sequence Positions
1-992
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P0C152
Species
Rattus norvegicus (Rat)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Tmem67 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Tmem67. It may not necessarily be applicable to this product.

NCBI GI #
114155689
NCBI GeneID
313067
NCBI Accession #
P0C152.1
UniProt Primary Accession #
P0C152
UniProt Related Accession #
P0C152
NCBI Official Full Name
Meckelin
NCBI Official Synonym Full Names
transmembrane protein 67
NCBI Official Symbol
Tmem67
NCBI Official Synonym Symbols
Wpk; Mks3
UniProt Protein Name
Meckelin
UniProt Synonym Protein Names
Meckel syndrome type 3 protein homolog; Transmembrane protein 67
Protein Family
Meckelin
UniProt Gene Name
Tmem67
UniProt Synonym Gene Names
Mks3; Wpk
NCBI Protein Information
meckelin

NCBI Summary for Tmem67

Meckelin is mutated in the wpk rat. [provided by RefSeq, Jul 2008]

UniProt Comments for Tmem67

Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. Essential for endoplasmic reticulum-associated degradation (ERAD) of surfactant protein C (sftpc) ().
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Research Articles on Tmem67

1. Data conclude that MKS3 is not important for formation of connecting cilium and rudimentary outer segments, but is critical for the maturation of outer segment processes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Tmem67 recombinant protein

 Reference Product  PubMed Publications
 FLNA recombinant protein  >12 publications with Tmem67 and FLNA

Pathways associated with Tmem67 recombinant protein

 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram

Organs/Tissues associated with Tmem67 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >11 publications with Tmem67 and Brain
 Lung Antibodies  >1 publications with Tmem67 and Lung
 Embryonic Tissue Antibodies  >1 publications with Tmem67 and Embryonic Tissue
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