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S-Adenosylmethionine Synthase Isoform Type-1 (MAT1A) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS954474

This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups… More details

$1135 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
S-adenosylmethionine synthase isoform type-1 (Mat1a), Recombinant Protein
Full Product Name
Recombinant Rat S-adenosylmethionine synthase isoform type-1 (Mat1a)
Product Gene Name
Mat1a recombinant protein
Sequence
MNGPVDGLCD HSLSEEGAFM FTSESVGEGH PDKICDQISD AVLDAHLKQD PNAKVACETV CKTGMVLLCG EITSMAMIDY QRVVRDTIKH IGYDDSAKGF DFKTCNVLVA LEQQSPDIAQ CVHLDRNEED VGAGDQGLMF GYATDETEEC MPLTIVLAHK LNTRMADLRR SGVLPWLRPD SKTQVTVQYV QDNGAVIPVR VHTIVISVQH NEDITLEAMR EALKEQVIKA VVPAKYLDED TIYHLQPSGR FVIGGPQGDA GVTGRKIIVD TYGGWGAHGG GAFSGKDYTK VDRSAAYAAR WVAKSLVKAG LCRRVLVQVS YAIGVAEPLS ISIFTYGTSK KTERDELLEV VNKNFDLRPG VIVRDLDLKK PIYQKTACYG HFGRSEFPWE VPKKLVF
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
43,698 Da
Sequence Positions
1-397, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P13444
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Mat1a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Mat1a purchase

MBS954474 is a recombinant protein targeting Mat1a. Also known as Recombinant Rat S-adenosylmethionine synthase isoform type-1 (Mat1a). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Mat1a. It may not necessarily be applicable to this product.

NCBI GI #
77157805
NCBI GeneID
25331
NCBI Accession #
NP_036992.2
UniProt Primary Accession #
P13444
UniProt Secondary Accession #
Q5FVU2
UniProt Related Accession #
P13444
GenBank Nucleotide #
NM_012860.2
NCBI Official Full Name
S-adenosylmethionine synthase isoform type-1
NCBI Official Synonym Full Names
methionine adenosyltransferase 1A
NCBI Official Symbol
Mat1a
NCBI Official Synonym Symbols
SAS; SADE; AdoMet
UniProt Protein Name
S-adenosylmethionine synthase isoform type-1
UniProt Synonym Protein Names
Methionine adenosyltransferase 1; MAT 1; Methionine adenosyltransferase I/III; MAT-I/III
Protein Family
S-adenosylmethionine synthase
UniProt Gene Name
Mat1a
UniProt Synonym Gene Names
Ams1; AdoMet synthase 1; MAT 1; MAT-I/III
NCBI Protein Information
S-adenosylmethionine synthase isoform type-1

NCBI Summary for Mat1a

enzyme that catalyzes the formation of S-adenosylmethionine [RGD, Feb 2006]

UniProt Comments for Mat1a

Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.

Research Articles on Mat1a

1. The oncogene PDRG1 is an interaction target of methionine adenosyltransferases.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Mat1a recombinant protein

 Reference Product  PubMed Publications
 Bhmt recombinant protein  >8 publications with Mat1a and Bhmt
 Ahcy recombinant protein  >6 publications with Mat1a and Ahcy
 Mtr recombinant protein  >4 publications with Mat1a and Mtr
 Dnmt1 recombinant protein  >3 publications with Mat1a and Dnmt1
 Dnmt3b recombinant protein  >2 publications with Mat1a and Dnmt3b

Pathways associated with Mat1a recombinant protein

 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 L-methionine Degradation I (to L-homocysteine) Pathway antibodies  L-methionine Degradation I (to L-homocysteine) Pathway Diagram
 L-methionine Salvage Cycle III Pathway antibodies  L-methionine Salvage Cycle III Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram

Diseases associated with Mat1a recombinant protein

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >86 publications with Mat1a and Liver Diseases
 Carcinoma Antibodies  >50 publications with Mat1a and Carcinoma
 Carcinoma, Hepatocellular Antibodies  >50 publications with Mat1a and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >47 publications with Mat1a and Liver Neoplasms
 Adenocarcinoma Antibodies  >33 publications with Mat1a and Adenocarcinoma
 Disease Models, Animal Antibodies  >21 publications with Mat1a and Disease Models, Animal
 Hypermethioninemia Antibodies  >19 publications with Mat1a and Hypermethioninemia
 Liver Cirrhosis Antibodies  >18 publications with Mat1a and Liver Cirrhosis
 Amino Acid Metabolism, Inborn Errors Antibodies  >13 publications with Mat1a and Amino Acid Metabolism, Inborn Errors
 Fatty Liver Antibodies  >13 publications with Mat1a and Fatty Liver

Organs/Tissues associated with Mat1a recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >118 publications with Mat1a and Liver
 Spleen Antibodies  >3 publications with Mat1a and Spleen
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