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Kit Ligand (KITLG) Sheep Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS954855

MBS954855 is a recombinant protein targeting KITLG. Also known as Recombinant Sheep Kit ligand (KITLG). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. KITLG; SCF More details

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Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Kit ligand (KITLG), Recombinant Protein
Full Product Name
Recombinant Sheep Kit ligand (KITLG)
Product Gene Name
KITLG recombinant protein
Product Synonym Gene Name
KITLG; SCF
Product Synonym Names
Kit ligand; Mast cell growth factor; MGF; Stem cell factor; SCF; c-Kit ligandCleaved into the following chain:; 1. Soluble KIT ligand; 2. sKITLG
Sequence
QGICR NRVTDDVKDV TKLVANLPKD YMITLKYVPG MDVLPSHCWI SEMVEQLSVS LTDLLDKFSN ISEGLSNYSI IDKLVKIVDD LVECMEEHSF ENVKKSSKSP EPRQFTPEKF FGIFNKSIDA FKDLEIVAST MSECVISSTS SPEKDSRVSV TKPFMLPPVA ASSLRNDSSS SNRKASNSIE DSSLQ
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
30,149 Da
Sequence Positions
26-215
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P79368
Species
Ovis aries (Sheep)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of KITLG recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KITLG. It may not necessarily be applicable to this product.

NCBI GI #
22654093
NCBI GeneID
443371
NCBI Accession #
P79368.2
UniProt Primary Accession #
P79368
UniProt Secondary Accession #
Q28591
UniProt Related Accession #
P79368
NCBI Official Full Name
Kit ligand
NCBI Official Symbol
KITLG
NCBI Official Synonym Symbols
MGF; SCF
UniProt Protein Name
Kit ligand
UniProt Synonym Protein Names
Mast cell growth factor; MGF; Stem cell factor; SCF; c-Kit ligandCleaved into the following chain:Soluble KIT ligand; sKITLG
Protein Family
Kit ligand
UniProt Gene Name
KITLG
UniProt Synonym Gene Names
SCF; MGF; SCF; sKITLG
UniProt Entry Name
SCF_SHEEP
NCBI Protein Information
kit ligand; c-Kit ligand; stem cell factor; mast cell growth factor

UniProt Comments for KITLG

Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with KITLG recombinant protein

 Reference Product  PubMed Publications
 FLNA recombinant protein  >12 publications with KITLG and FLNA

Pathways associated with KITLG recombinant protein

 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
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