Granulocyte Colony Stimulating Factor (GCSF) ELISA Kit for Human

Name: Human GCSF ELISA Kit; Granulocyte Colony Stimulating Factor; MyBioSource
Brand: MyBioSource
SKU: MBS009567
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS009567

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of GCSF (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates,… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Granulocyte Colony Stimulating Factor (GCSF), ELISA Kit

Full Product Name

Human Granulocyte Colony Stimulating Factor ELISA Kit

Product Gene Name

GCSF elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Body fluids, tissue homogenates, secretions or feces samples

Detection Range

6.25pg/ml-200pg/ml

Sensitivity

1.0pg/ml.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%

Molecular Weight

22,293 Da

Chromosome Location

Chromosome: 17; NC_000017.10 (38171614..38174066). Location: 17q11.2-q12

OMIM

138970

3D Structure

ModBase 3D Structure for P09919

Other Notes

Small volumes of GCSF elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GCSF purchase

MBS009567 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Granulocyte Colony Stimulating Factor (GCSF) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GCSF. The ELISA analytical biochemical technique of the MBS009567 kit is based on GCSF antibody-GCSF antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GCSF antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GCSF. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GCSF. It may not necessarily be applicable to this product.

NCBI GI #

296011057

NCBI GeneID

1440

NCBI Accession #

NP_001171618.1

UniProt Primary Accession #

P09919

UniProt Secondary Accession #

A8MXR7

UniProt Related Accession #

P09919

GenBank Nucleotide #

NM_001178147.1

NCBI Official Full Name

granulocyte colony-stimulating factor isoform d

NCBI Official Synonym Full Names

colony stimulating factor 3 (granulocyte)

NCBI Official Symbol

CSF3

NCBI Official Synonym Symbols

GCSF; CSF3OS; C17orf33

UniProt Protein Name

Granulocyte colony-stimulating factor

UniProt Synonym Protein Names

Pluripoietin

Protein Family

Granulocyte colony-stimulating factor

UniProt Gene Name

CSF3

UniProt Synonym Gene Names

C17orf33; GCSF; G-CSF

UniProt Entry Name

CSF3_HUMAN

NCBI Protein Information

granulocyte colony-stimulating factor; filgrastim; lenograstim; pluripoietin

NCBI Summary for GCSF

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]

UniProt Comments for GCSF

G-CSF: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Secreted; Secreted, signal peptide; Cytokine

Chromosomal Location of Human Ortholog: 17q11.2-q12

Cellular Component: extracellular space

Molecular Function: enzyme binding; growth factor activity; cytokine activity; granulocyte colony-stimulating factor receptor binding

Biological Process: positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein kinase B signaling cascade; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of actin filament polymerization; positive regulation of protein binding; granulocyte differentiation; positive regulation of myeloid cell differentiation; multicellular organismal development; cytokine and chemokine mediated signaling pathway; positive regulation of cell proliferation; positive regulation of transcription factor import into nucleus; immune response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of peptidyl-serine phosphorylation

Research Articles on GCSF

1. Administration of G-CSF in a dosage regimen commonly used for bone marrow donors is well tolerated and safe, and provides a signal of positive change in a task of cognitive performance in 8 patients with mild to moderate stage Alzheimer's disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GCSF elisa kit

Reference Product	PubMed Publications
CSF2 elisa kit	>14 publications with GCSF and CSF2
CSF3R elisa kit	>11 publications with GCSF and CSF3R
MMP9 elisa kit	>5 publications with GCSF and MMP9
IL10 elisa kit	>4 publications with GCSF and IL10
CXCL12 elisa kit	>3 publications with GCSF and CXCL12
SELL elisa kit	>1 publications with GCSF and SELL
STAT3 elisa kit	>1 publications with GCSF and STAT3
CXCR4 elisa kit	>1 publications with GCSF and CXCR4

Pathways associated with GCSF elisa kit

Products by Pathway	Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokines And Inflammatory Response Pathway antibodies	Cytokines And Inflammatory Response Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Malaria Pathway antibodies	Malaria Pathway Diagram
Malaria Pathway antibodies	Malaria Pathway Diagram
PI3K-Akt Signaling Pathway antibodies	PI3K-Akt Signaling Pathway Diagram

Diseases associated with GCSF elisa kit

Disease Name	Pubmed Publications
Disease Susceptibility Antibodies	>6 publications with GCSF and Disease Susceptibility
Nervous System Diseases Antibodies	>4 publications with GCSF and Nervous System Diseases
Neutropenia Antibodies	>3 publications with GCSF and Neutropenia
Leukopenia Antibodies	>2 publications with GCSF and Leukopenia
Anemia Antibodies	>2 publications with GCSF and Anemia
Leukemia, Myeloid, Acute Antibodies	>2 publications with GCSF and Leukemia, Myeloid, Acute
Breast Neoplasms Antibodies	>1 publications with GCSF and Breast Neoplasms
Peripheral Nervous System Diseases Antibodies	>1 publications with GCSF and Peripheral Nervous System Diseases
Pulmonary Fibrosis Antibodies	>1 publications with GCSF and Pulmonary Fibrosis
Brain Injuries Antibodies	>1 publications with GCSF and Brain Injuries

Organs/Tissues associated with GCSF elisa kit

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>5 publications with GCSF and Skin
Lung Antibodies	>3 publications with GCSF and Lung
Muscle Antibodies	>2 publications with GCSF and Muscle
Liver Antibodies	>1 publications with GCSF and Liver
Brain Antibodies	>1 publications with GCSF and Brain
Uterus Antibodies	>1 publications with GCSF and Uterus
Uncharacterized Tissue Antibodies	>1 publications with GCSF and Uncharacterized Tissue