Human OGN Recombinant Protein – Cat# MBS957464

Mimecan (OGN) Human Recombinant Protein

Name: OGN Recombinant Protein; Mimecan; Human; MyBioSource
Brand: MyBioSource
SKU: MBS957464
Price: 385 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS957464

MBS957464 is a recombinant protein targeting OGN. Also known as Recombinant Human Mimecan. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2. More details

$385 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Mimecan (OGN), Recombinant Protein

Full Product Name

Recombinant Human Mimecan

Product Gene Name

OGN recombinant protein

Product Synonym Names

Osteoglycin; Osteoinductive factor; OIF

Sequence

PPTQQDSRII YDYGTDNFEE SIFSQDYEDK YLDGKNIKEK ETVIIPNEKS LQLQKDEAIT PLPPKKENDE MPTCLLCVCL SGSVYCEEVD IDAVPPLPKE SAYLYARFNK IKKLTAKDFA DIPNLRRLDF TGNLIEDIED GTFSKLSLLE ELSLAENQLL KLPVLPPKLT LFNAKYNKIK SRGIKANAFK KLNNLTFLYL DHNALESVPL NLPESLRVIH LQFNNIASIT DDTFCKANDT SYIRDRIEEI RLEGNPIVLG KHPNSFICLK RLPIGSYF

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

Molecular Weight

33.7 kDa

Sequence Positions

21-298. Full Length of Mature Protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

602383

3D Structure

ModBase 3D Structure for P20774

Product Categories/Family for OGN recombinant protein

Signal Transduction

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Product References and Citations for OGN recombinant protein

Molecular cloning of a novel bone-forming compound osteoinductive factor.Madisen L., Neubauer M., Plowman G., Rosen D.M., Segarini P.R., Dasch J.R., Thompson A.Y., Ziman J., Bentz H., Purchio A.F.DNA Cell Biol. 9:303-309(1990)

Other Notes

Small volumes of OGN recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for OGN. It may not necessarily be applicable to this product.

NCBI GI #

7661704

NCBI GeneID

4969

NCBI Accession #

NP_054776.1

UniProt Primary Accession #

P20774

UniProt Secondary Accession #

Q6FIB0; Q9UF90; Q9UNK5

UniProt Related Accession #

P20774

GenBank Nucleotide #

NM_014057.4

NCBI Official Full Name

mimecan isoform 2

NCBI Official Synonym Full Names

osteoglycin

NCBI Official Symbol

OGN

NCBI Official Synonym Symbols

OG; OIF; SLRR3A

UniProt Protein Name

Mimecan

UniProt Synonym Protein Names

Osteoglycin; Osteoinductive factor; OIF

Protein Family

Mimecan

UniProt Gene Name

OGN

UniProt Synonym Gene Names

OIF; SLRR3A; OIF

UniProt Entry Name

MIME_HUMAN

NCBI Protein Information

mimecan

NCBI Summary for OGN

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

UniProt Comments for OGN

OGN: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9q22

Cellular Component: extracellular matrix; extracellular region; extracellular space; Golgi lumen; lysosomal lumen; proteinaceous extracellular matrix

Molecular Function: growth factor activity; heparin binding; protein binding; Roundabout binding

Biological Process: axon extension involved in axon guidance; axonogenesis; carbohydrate metabolic process; glycosaminoglycan metabolic process; keratan sulfate biosynthetic process; keratan sulfate catabolic process; keratan sulfate metabolic process; negative regulation of smooth muscle cell proliferation; regulation of axonogenesis

Research Articles on OGN

1. OGN might play a role in the development of Ovarian Cancer, and may be a therapeutic target in OC.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with OGN recombinant protein

Reference Product	PubMed Publications
OMD recombinant protein	>5 publications with OGN and OMD
PRELP recombinant protein	>4 publications with OGN and PRELP
KERA recombinant protein	>4 publications with OGN and KERA
LUM recombinant protein	>2 publications with OGN and LUM
FMOD recombinant protein	>1 publications with OGN and FMOD
CHST6 recombinant protein	>1 publications with OGN and CHST6

Pathways associated with OGN recombinant protein

Products by Pathway	Pathway Diagram
Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway antibodies	Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway Diagram
Defective CHST6 Causes MCDC1 Pathway antibodies	Defective CHST6 Causes MCDC1 Pathway Diagram
Defective ST3GAL3 Causes MCT12 And EIEE15 Pathway antibodies	Defective ST3GAL3 Causes MCT12 And EIEE15 Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Diseases Associated With Glycosaminoglycan Metabolism Pathway antibodies	Diseases Associated With Glycosaminoglycan Metabolism Pathway Diagram
Diseases Of Glycosylation Pathway antibodies	Diseases Of Glycosylation Pathway Diagram
Glycosaminoglycan Metabolism Pathway antibodies	Glycosaminoglycan Metabolism Pathway Diagram
Keratan Sulfate Biosynthesis Pathway antibodies	Keratan Sulfate Biosynthesis Pathway Diagram
Keratan Sulfate Degradation Pathway antibodies	Keratan Sulfate Degradation Pathway Diagram
Keratan Sulfate/keratin Metabolism Pathway antibodies	Keratan Sulfate/keratin Metabolism Pathway Diagram

Diseases associated with OGN recombinant protein

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>12 publications with OGN and Cardiovascular Diseases
Brain Diseases Antibodies	>6 publications with OGN and Brain Diseases
Hypertrophy Antibodies	>4 publications with OGN and Hypertrophy
Hypertension Antibodies	>4 publications with OGN and Hypertension
Disease Models, Animal Antibodies	>4 publications with OGN and Disease Models, Animal
Fibrosis Antibodies	>3 publications with OGN and Fibrosis
Inflammation Antibodies	>3 publications with OGN and Inflammation
Atherosclerosis Antibodies	>2 publications with OGN and Atherosclerosis
Liver Neoplasms Antibodies	>2 publications with OGN and Liver Neoplasms
Neoplasm Metastasis Antibodies	>2 publications with OGN and Neoplasm Metastasis

Organs/Tissues associated with OGN recombinant protein

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>36 publications with OGN and Bone
Connective Tissue Antibodies	>20 publications with OGN and Connective Tissue
Eye Antibodies	>18 publications with OGN and Eye
Muscle Antibodies	>13 publications with OGN and Muscle
Brain Antibodies	>13 publications with OGN and Brain
Heart Antibodies	>8 publications with OGN and Heart
Vascular Antibodies	>6 publications with OGN and Vascular
Embryonic Tissue Antibodies	>5 publications with OGN and Embryonic Tissue
Nerve Antibodies	>5 publications with OGN and Nerve
Pituitary Gland Antibodies	>4 publications with OGN and Pituitary Gland