T Cell Receptor Alpha Constant (TRAC) Human Recombinant Protein

MBS957674 is a recombinant protein targeting TRAC. Also known as Recombinant Human T cell receptor alpha constant (TRAC). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

The chromosomal location of T-cell receptor genes and a T cell rearranging gene possible correlation with specific translocations in human T cell leukaemia.Rabbitts T.H., Lefranc M.P., Stinson M.A., Sims J.E., Schroder J., Steinmetz M., Spurr N.L., Solomon E., Goodfellow P.N.EMBO J. 4:1461-1465(1985) Analysis of cDNA clones specific for human T cells and the alpha and beta chains of the T-cell receptor heterodimer from a human T-cell line.Yanagi Y., Chan A., Chin B., Minden M., Mak T.W.Proc. Natl. Acad. Sci. U.S.A. 82:3430-3434(1985) Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D.Nat. Biotechnol. 27:378-386(2009) Mutation in the TCRalpha subunit constant gene (TRAC) leads to a human immunodeficiency disorder characterized by a lack of TCRalphabeta+ T cells.Morgan N.V., Goddard S., Cardno T.S., McDonald D., Rahman F., Barge D., Ciupek A., Straatman-Iwanowska A., Pasha S., Guckian M., Anderson G., Huissoon A., Cant A., Tate W.P., Hambleton S., Maher E.R.J. Clin. Invest. 121:695-702(2011) The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance.Kjer-Nielsen L., Clements C.S., Brooks A.G., Purcell A.W., McCluskey J., Rossjohn J.Structure 10:1521-1532(2002) A structural basis for immunodominant human T cell receptor recognition.Stewart-Jones G.B.E., McMichael A.J., Bell J.I., Stuart D.I., Jones E.Y.Nat. Immunol. 4:657-663(2003) Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule.Li Y., Huang Y., Lue J., Quandt J.A., Martin R., Mariuzza R.A.EMBO J. 24:2968-2979(2005)

Small volumes of TRAC recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.