Human CALD1 Recombinant Protein – Cat# MBS958308

Caldesmon (CALD1) Human Recombinant Protein

Name: CALD1 Recombinant Protein; Caldesmon; Human; MyBioSource
Brand: MyBioSource
SKU: MBS958308
Price: 1675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS958308

This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin,… More details

$1675 / 0.02 mg (E-Coli) +2 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Caldesmon (CALD1), Recombinant Protein

Full Product Name

Recombinant Human Caldesmon (CALD1)

Product Gene Name

CALD1 recombinant protein

Sequence

MDDFERRREL RRQKREEMRL EAERIAYQRN DDDEEEAARE RRRRARQERL RQKQEEESLG QVTDQVEVNA QNSVPDEEAK TTTTNTQVEG DDEAAFLERL ARREERRQKR LQEALERQKE FDPTITDASL SLPSRRMQND TAENETTEKE EKSESRQERY EIEETETVTK SYQKNDWRDA EENKKEDKEK EEEEEEKPKR GSIGENQVEV MVEEKTTESQ EETVVMSLKN GQISSEEPKQ EEEREQGSDE ISHHEKMEEE DKERAEAERA RLEAEERERI KAEQDKKIAD ERARIEAEEK AAAQERERRE AEERERMREE EKRAAEERQR IKEEEKRAAE ERQRIKEEEK RAAEERQRIK EEEKRAAEER QRARAEEEEK AKVEEQKRNK QLEEKKHAMQ ETKIKGEKVE QKIEGKWVNE KKAQEDKLQT AVLKKQGEEK GTKVQAKREK LQEDKPTFKK EEIKDEKIKK DKEPKEEVKS FMDRKKGFTE VKSQNGEFMT HKLKHTENTF SRPGGRASVD TKEAEGAPQV EAGKRLEELR RRRGETESEE FEKLKQKQQE AALELEELKK KREERRKVLE EEEQRRKQEE ADRKLREEEE KRRLKEEIER RRAEAAEKRQ KMPEDGLSDD KKPFKCFTPK GSSLKIEERA EFLNKSVQKS SGVKSTHQAA IVSKIDSRLE QYTSAIEGTK SAKPTKPAAS DLPVPAEGVR NIKSMWEKGN VFSSPTAAGT PNKETAGLKV GVSSRINEWL TKTPDGNKSP APKPSDLRPG DVSSKRNLWE KQSVDKVTSP TKV

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

65,620 Da

Sequence Positions

1-793, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

114213

3D Structure

ModBase 3D Structure for Q05682

Species

Human

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CALD1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CALD1 purchase

MBS958308 is a recombinant protein targeting CALD1. Also known as Recombinant Human Caldesmon (CALD1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for CALD1. It may not necessarily be applicable to this product.

NCBI GI #

4826657

NCBI GeneID

800

NCBI Accession #

NP_004333.1

UniProt Primary Accession #

Q05682

UniProt Secondary Accession #

Q13978; Q13979; Q14741; Q14742; Q9UD91; A8K0X1

UniProt Related Accession #

Q05682

GenBank Nucleotide #

NM_004342.6

NCBI Official Full Name

caldesmon isoform 2

NCBI Official Synonym Full Names

caldesmon 1

NCBI Official Symbol

CALD1

NCBI Official Synonym Symbols

CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22

UniProt Protein Name

Caldesmon

Protein Family

Caldesmon

UniProt Gene Name

CALD1

UniProt Synonym Gene Names

CAD; CDM; CDM

NCBI Protein Information

caldesmon

UniProt Comments for CALD1

Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration ().

Research Articles on CALD1

1. rs 3807337 polymorphism of CALD1 gene is associated with diabetic nephropathy occurrence in type 1 diabetes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CALD1 recombinant protein

Reference Product	PubMed Publications
TPM1 recombinant protein	>3 publications with CALD1 and TPM1
VCL recombinant protein	>2 publications with CALD1 and VCL

Pathways associated with CALD1 recombinant protein

Products by Pathway	Pathway Diagram
Muscle Contraction Pathway antibodies	Muscle Contraction Pathway Diagram
Myometrial Relaxation And Contraction Pathways antibodies	Myometrial Relaxation And Contraction Pathways Diagram
Smooth Muscle Contraction Pathway antibodies	Smooth Muscle Contraction Pathway Diagram
Vascular Smooth Muscle Contraction Pathway antibodies	Vascular Smooth Muscle Contraction Pathway Diagram
Vascular Smooth Muscle Contraction Pathway antibodies	Vascular Smooth Muscle Contraction Pathway Diagram

Diseases associated with CALD1 recombinant protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>4 publications with CALD1 and Neoplasms
Nervous System Diseases Antibodies	>1 publications with CALD1 and Nervous System Diseases
Movement Disorders Antibodies	>1 publications with CALD1 and Movement Disorders
Neoplasms, Experimental Antibodies	>1 publications with CALD1 and Neoplasms, Experimental
Urinary Bladder Neoplasms Antibodies	>1 publications with CALD1 and Urinary Bladder Neoplasms
Inflammation Antibodies	>1 publications with CALD1 and Inflammation
Prenatal Exposure Delayed Effects Antibodies	>1 publications with CALD1 and Prenatal Exposure Delayed Effects
Hyperplasia Antibodies	>1 publications with CALD1 and Hyperplasia

Organs/Tissues associated with CALD1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>5 publications with CALD1 and Muscle
Blood Antibodies	>3 publications with CALD1 and Blood
Prostate Antibodies	>2 publications with CALD1 and Prostate
Brain Antibodies	>2 publications with CALD1 and Brain
Bladder Antibodies	>1 publications with CALD1 and Bladder
Lung Antibodies	>1 publications with CALD1 and Lung
Vascular Antibodies	>1 publications with CALD1 and Vascular
Intestine Antibodies	>1 publications with CALD1 and Intestine