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Acyloxyacyl Hydrolase (AOAH) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Popular Catalog #: MBS958374

Acyloxyacyl hydrolase (AOAH) is a 2-subunit lipase which selectively hydrolyzes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial endotoxins. AOAH may modulate host inflammatory responses to gram-negative bacterial… More details

$345 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Acyloxyacyl hydrolase (AOAH), Recombinant Protein
Full Product Name
Recombinant Human Acyloxyacyl hydrolase (AOAH)
Product Gene Name
Sequence
LSNGHTCVGC VLVVSVIEQL AQVHNSTVQA SMERLCSYLP EKLFLKTTCY LVIDKFGSDI IKLLSADMNA DVVCHTLEFC KQNTGQPLCH LYPLPKETWK FTLQKARQIV KKSPILKYSR SGSDICSLPV LAKICQKIKL AMEQSVPFKD VDSDKYSVFP TLRGYHWRGR DCNDSDESVY PGRRPNNWDV HQDSNCNGIW GVDPKDGVPY EKKFCEGSQP RGIILLGDSA GAHFHISPEW ITASQMSLNS FINLPTALTN ELDWPQLSGA TGFLDSTVGI KEKSIYLRLW KRNHCNHRDY QNISRNGASS RNLKKFIESL SRNKVLDYPA IVIYAMIGND VCSGKSDPVP AMTTPEKLYS NVMQTLKHLN SHLPNGSHVI LYGLPDGTFL WDNLHNRYHP LGQLNKDMTY AQLYSFLNCL QVSPCHGWMS SNKTLRTLTS ERAEQLSNTL KKIAASEKFT NFNLFYMDFA FHEIIQEWQK RGGQPWQLIE PVDGFHPNEV ALLLLADHFW KKVQLQWPQI LGKENPFNPQ IKQVFGDQGG H
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
61,647 Da
Sequence Positions
35-575aa; Full Length of Mature Protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
102593
3D Structure
ModBase 3D Structure for P28039
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of AOAH recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AOAH purchase

MBS958374 is a recombinant protein targeting AOAH. Also known as Recombinant Human Acyloxyacyl hydrolase (AOAH). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for AOAH. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
acyloxyacyl hydrolase isoform 2 preproprotein
NCBI Official Synonym Full Names
acyloxyacyl hydrolase
NCBI Official Symbol
AOAH
UniProt Protein Name
Acyloxyacyl hydrolase
Protein Family
UniProt Gene Name
AOAH
NCBI Protein Information
acyloxyacyl hydrolase

NCBI Summary for AOAH

This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Apr 2010]
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UniProt Comments for AOAH

Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides (PubMed:1883828, PubMed:8089145). By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses (). In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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