Rat MAS1 Recombinant Protein – Cat# MBS959036

Proto-Oncogene Mas (MAS1) Rat Recombinant Protein

Name: MAS1 Recombinant Protein; Proto-Oncogene Mas; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS959036
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS959036

MBS959036 is a recombinant protein targeting Mas1. Also known as Recombinant Rat Proto-oncogene Mas (Mas1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Proto-oncogene Mas (Mas1), Recombinant Protein

Full Product Name

Recombinant Rat Proto-oncogene Mas (Mas1)

Product Gene Name

Mas1 recombinant protein

Product Synonym Gene Name

Mas1; Mas, Mas-1

Product Synonym Names

Recombinant Proto-oncogene Mas (Mas1); Proto-oncogene Mas

Sequence

MDQSNMTSFA EEKAMNTSSR NASLGTSHPP IPIVHWVIMS ISPLGFVENG ILLWFLCFRM RRNPFTVYIT HLSIADISLL FCIFILSIDY ALDYELSSGH YYTIVTLSVT FLFGYNTGLY LLTAISVERC LSVLYPIWYR CHRPKHQSAF VCALLWALSC LVTTMEYVMC IDSGEESHSQ SDCRAVIIFI AILSFLVFTP LMLVSSTILV VKIRKNTWAS HSSKLYIVIM VTIIIFLIFA MPMRVLYLLY YEYWSTFGNL HNISLLFSTI NSSANPFIYF FVGSSKKKRF RESLKVVLTR AFKDEMQPRR QEGNGNTVSI ETVV

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

37,131 Da

Sequence Positions

1-324

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 1; NC_005100.3 (51644720..51675365, complement). Location: 1q11-q12

3D Structure

ModBase 3D Structure for P12526

Species

Rattus norvegicus (Rat)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Mas1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Mas1. It may not necessarily be applicable to this product.

NCBI GI #

6981186

NCBI GeneID

25153

NCBI Accession #

NP_036889.1

UniProt Primary Accession #

P12526

UniProt Related Accession #

P12526

GenBank Nucleotide #

NM_012757.2

NCBI Official Full Name

proto-oncogene Mas

NCBI Official Synonym Full Names

MAS1 oncogene

NCBI Official Symbol

Mas1

NCBI Official Synonym Symbols

c-mas

UniProt Protein Name

Proto-oncogene Mas

Protein Family

Agropine synthesis reductase

UniProt Gene Name

Mas1

UniProt Synonym Gene Names

Mas; Mas-1

UniProt Entry Name

MAS_RAT

NCBI Protein Information

proto-oncogene Mas; MAS proto-oncogene; angiotensin-(1-7) receptor

NCBI Summary for Mas1

oncogene; may be involved in function or development of neural tissues [RGD, Feb 2006]

UniProt Comments for Mas1

MAS1: Receptor for angiotensin 1-7. Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1. The MAS oncogene has a weak focus-inducing activity in transfected NIH 3T3 cells. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; Oncoprotein; Membrane protein, integral; GPCR, family 1

Cellular Component: cell surface; integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; peptide hormone binding; peptide binding; angiotensin receptor activity

Biological Process: response to drug; response to peptide hormone stimulus; G-protein coupled receptor protein signaling pathway; negative regulation of protein amino acid phosphorylation; regulation of inflammatory response; male gonad development; hippocampus development; positive regulation of cell proliferation; activation of NF-kappaB-inducing kinase; spermatogenesis; response to activity; positive regulation of DNA replication

Research Articles on Mas1

1. data indicate that Mas expression is responsive to different pathological stimuli, thereby suggesting that Mas receptor is involved in the homeostasis of the heart, as well as in the establishment and progression of cardiac diseases

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Mas1 recombinant protein

Products by Pathway	Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Renin - Angiotensin System Pathway antibodies	Renin - Angiotensin System Pathway Diagram
Renin-angiotensin System Pathway antibodies	Renin-angiotensin System Pathway Diagram
Renin-angiotensin System Pathway antibodies	Renin-angiotensin System Pathway Diagram

Diseases associated with Mas1 recombinant protein

Disease Name	Pubmed Publications
Pain Antibodies	>2 publications with Mas1 and Pain
Inflammation Antibodies	>1 publications with Mas1 and Inflammation
Myocarditis Antibodies	>1 publications with Mas1 and Myocarditis
Nervous System Diseases Antibodies	>1 publications with Mas1 and Nervous System Diseases
Heart Diseases Antibodies	>1 publications with Mas1 and Heart Diseases
Fibrosis Antibodies	>1 publications with Mas1 and Fibrosis
Drug Toxicity Antibodies	>1 publications with Mas1 and Drug Toxicity
Hypertension Antibodies	>1 publications with Mas1 and Hypertension

Organs/Tissues associated with Mas1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>1 publications with Mas1 and Heart