ATP Synthase Lipid-Binding Protein, Mitochondrial (ATP5G2) Rat Recombinant Protein

ATP5G2: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element. Belongs to the ATPase C chain family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: mitochondrion; proton-transporting ATP synthase complex, coupling factor F(o); mitochondrial membrane; integral to membrane

Molecular Function: hydrogen ion transmembrane transporter activity; lipid binding

Biological Process: ATP synthesis coupled proton transport; response to ethanol; ATP hydrolysis coupled proton transport