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Carnitine O-Palmitoyltransferase 1, Liver Isoform (CPT1A) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS959350

MBS959350 is a recombinant protein targeting Cpt1a. Also known as Recombinant Rat Carnitine O-palmitoyltransferase 1, liver isoform (Cpt1a). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$975 / 0.05 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Carnitine O-palmitoyltransferase 1, liver isoform (Cpt1a), Recombinant Protein
Full Product Name
Recombinant Rat Carnitine O-palmitoyltransferase 1, liver isoform (Cpt1a)
Product Gene Name
Cpt1a recombinant protein
Product Synonym Gene Name
Cpt1a; Cpt-1, Cpt1
Product Synonym Names
Recombinant Carnitine O-palmitoyltransferase 1, liver isoform (Cpt1a); Carnitine O-palmitoyltransferase 1, liver isoform; CPT1-L EC= 2.3.1.21; Carnitine O-palmitoyltransferase I, liver isoform; CPT I; CPTI-L Carnitine palmitoyltransferase 1A
Sequence
MATDVFQLGY SEDGHCKGDT NPNIPKPTRL QWDIPGECQE VIDASLSSAS LLANDVDLHS FPFDSFGKGL IKKCRTSPDA FIQLALQLAH YKDMGKFCLT YEASMTRLFR EGRTETVRSC TMESCNFVQA MMDPKSTAEQ RLKLFKIACE KHQHLYRLAM TGAGIDRHLF CLYVVSKYLA VDSPFLKEVL SEPWRLSTSQ TPQQQVELFD FEKNPDYVSC GGGFGPVADD GYGVSYIIVG ENFIHFHISS KFSSPETDSH RFGKHLRQAM MDIITLFGLT INSKK
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
88,125 Da
Sequence Positions
489-773. Partial.
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 1; NC_005100.3 (225437309..225497586). Location: 1q43
3D Structure
ModBase 3D Structure for P32198
Species
Rattus norvegicus (Rat)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Cpt1a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Cpt1a. It may not necessarily be applicable to this product.

NCBI GI #
162287173
NCBI GeneID
25757
NCBI Accession #
NP_113747.2
UniProt Primary Accession #
P32198
UniProt Secondary Accession #
P97780; Q6IMZ4
UniProt Related Accession #
P32198
GenBank Nucleotide #
NM_031559.2
NCBI Official Full Name
carnitine O-palmitoyltransferase 1, liver isoform
NCBI Official Synonym Full Names
carnitine palmitoyltransferase 1a, liver
NCBI Official Symbol
Cpt1a
NCBI Official Synonym Symbols
CPT-Ia
UniProt Protein Name
Carnitine O-palmitoyltransferase 1, liver isoform
UniProt Synonym Protein Names
Carnitine O-palmitoyltransferase I, liver isoform; CPT I; CPTI-L; Carnitine palmitoyltransferase 1A
Protein Family
Carnitine O-palmitoyltransferase
UniProt Gene Name
Cpt1a
UniProt Synonym Gene Names
Cpt-1; Cpt1; CPT1-L; CPT I; CPTI-L
UniProt Entry Name
CPT1A_RAT
NCBI Protein Information
carnitine O-palmitoyltransferase 1, liver isoform; CPT I; CPT1-L; CPTI-L; carnitine palmitoyltransferase 1, liver; carnitine O-palmitoyltransferase I, liver isoform; Carnitine palmitoyltransferase 1 alpha, liver isoform

NCBI Summary for Cpt1a

enzyme that catalyses the transfer of long chain fatty acids to carnitine for translocation across the mitochondrial inner membrane [RGD, Feb 2006]

UniProt Comments for Cpt1a

CPT1A: Belongs to the carnitine/choline acetyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Lipid Metabolism - fatty acid; Mitochondrial; EC 2.3.1.21; Membrane protein, multi-pass; Transferase

Cellular Component: mitochondrial outer membrane; endoplasmic reticulum membrane; intracellular membrane-bound organelle; membrane; mitochondrion; mitochondrial inner membrane; integral to membrane; integral to mitochondrial outer membrane

Molecular Function: identical protein binding; protein binding; carnitine O-palmitoyltransferase activity

Biological Process: response to drug; eating behavior; glucose metabolic process; long-chain fatty acid metabolic process; response to organic cyclic substance; positive regulation of fatty acid beta-oxidation; fatty acid beta-oxidation; triacylglycerol metabolic process; epithelial cell differentiation; transport; regulation of fatty acid oxidation; regulation of fatty acid beta-oxidation; carnitine metabolic process; regulation of insulin secretion; protein homooligomerization
Show more

Research Articles on Cpt1a

1. -L-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the L-carnitine content in the rat heart

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Cpt1a recombinant protein

 Products by Pathway  Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Beta Oxidation Meta Pathway antibodies  Beta Oxidation Meta Pathway Diagram
 Circadian Clock Pathway antibodies  Circadian Clock Pathway Diagram
 Fatty Acid Beta Oxidation Pathway antibodies  Fatty Acid Beta Oxidation Pathway Diagram
 Fatty Acid Beta Oxidation 1 Pathway antibodies  Fatty Acid Beta Oxidation 1 Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Import Of Palmitoyl-CoA Into The Mitochondrial Matrix Pathway antibodies  Import Of Palmitoyl-CoA Into The Mitochondrial Matrix Pathway Diagram

Diseases associated with Cpt1a recombinant protein

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >47 publications with Cpt1a and Fatty Liver
 Liver Diseases Antibodies  >22 publications with Cpt1a and Liver Diseases
 Obesity Antibodies  >20 publications with Cpt1a and Obesity
 Insulin Resistance Antibodies  >16 publications with Cpt1a and Insulin Resistance
 Hyperinsulinism Antibodies  >11 publications with Cpt1a and Hyperinsulinism
 Neoplasms Antibodies  >11 publications with Cpt1a and Neoplasms
 Inflammation Antibodies  >8 publications with Cpt1a and Inflammation
 Liver Neoplasms Antibodies  >6 publications with Cpt1a and Liver Neoplasms
 Diabetes Mellitus Antibodies  >6 publications with Cpt1a and Diabetes Mellitus
 Carcinoma, Hepatocellular Antibodies  >4 publications with Cpt1a and Carcinoma, Hepatocellular

Organs/Tissues associated with Cpt1a recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >65 publications with Cpt1a and Liver
 Brain Antibodies  >9 publications with Cpt1a and Brain
 Kidney Antibodies  >7 publications with Cpt1a and Kidney
 Heart Antibodies  >6 publications with Cpt1a and Heart
 Connective Tissue Antibodies  >4 publications with Cpt1a and Connective Tissue
 Eye Antibodies  >1 publications with Cpt1a and Eye
 Pancreas Antibodies  >1 publications with Cpt1a and Pancreas
 Placenta Antibodies  >1 publications with Cpt1a and Placenta
 Colon Antibodies  >1 publications with Cpt1a and Colon
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