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Cell Division Control Protein 42 Homolog (CDC42) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS959540

This protein is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces… More details

$830 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cell division control protein 42 homolog (Cdc42), Recombinant Protein
Full Product Name
Recombinant Mouse Cell division control protein 42 homolog (Cdc42)
Product Gene Name
Cdc42 recombinant protein
Sequence
MQTIKCVVVG DGAVGKTCLL ISYTTNKFPS EYVPTVFDNY AVTVMIGGEP YTLGLFDTAG QEDYDRLRPL SYPQTDVFLV CFSVVSPSSF ENVKEKWVPE ITHHCPKTPF LLVGTQIDLR DDPSTIEKLA KNKQKPITPE TAEKLARDLK AVKYVECSAL TQKGLKNVFD EAILAALEPP EPKKSRRC
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
21,311 Da
Sequence Positions
1-188, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P60766
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Cdc42 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cdc42 purchase

MBS959540 is a recombinant protein targeting Cdc42. Also known as Recombinant Mouse Cell division control protein 42 homolog (Cdc42). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Cdc42. It may not necessarily be applicable to this product.

NCBI GI #
344313177
NCBI GeneID
12540
NCBI Accession #
NP_001230698.1
UniProt Primary Accession #
P60766
UniProt Secondary Accession #
P21181; P25763; Q3THZ7; Q3TJK6; Q545V0; Q6P201; Q8BQ51; A2A9U6
UniProt Related Accession #
P60766
GenBank Nucleotide #
NM_001243769.1
NCBI Official Full Name
cell division control protein 42 homolog isoform 2
NCBI Official Synonym Full Names
cell division cycle 42
NCBI Official Symbol
Cdc42
NCBI Official Synonym Symbols
AI747189; AU018915
UniProt Protein Name
Cell division control protein 42 homolog
UniProt Synonym Protein Names
G25K GTP-binding protein
Protein Family
Cdc42
UniProt Gene Name
Cdc42
NCBI Protein Information
cell division control protein 42 homolog

UniProt Comments for Cdc42

Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration (). Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons (PubMed:25851601). Facilitates filopodia formation upon DOCK11-activation (PubMed:22494997). Also plays a role in phagocytosis through organization of the F-actin cytoskeleton associated with forming phagocytic cups ().
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Research Articles on Cdc42

1. We conclude that CRN7 spatiotemporally influences F-actin organization and Golgi integrity in a Cdc42- and N-WASP-dependent manner.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Cdc42 recombinant protein

 Reference Product  PubMed Publications
 Pak1 recombinant protein  >269 publications with Cdc42 and Pak1
 Pak3 recombinant protein  >36 publications with Cdc42 and Pak3
 Baiap2 recombinant protein  >22 publications with Cdc42 and Baiap2
 Cdc42ep4 recombinant protein  >11 publications with Cdc42 and Cdc42ep4
 Diap2 recombinant protein  >7 publications with Cdc42 and Diap2
 Cdc42ep5 recombinant protein  >7 publications with Cdc42 and Cdc42ep5
 Cdc42ep1 recombinant protein  >7 publications with Cdc42 and Cdc42ep1

Pathways associated with Cdc42 recombinant protein

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 CD28 Co-stimulation Pathway antibodies  CD28 Co-stimulation Pathway Diagram
 CD28 Dependent Vav1 Pathway antibodies  CD28 Dependent Vav1 Pathway Diagram

Diseases associated with Cdc42 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >564 publications with Cdc42 and Neoplasms
 Carcinoma Antibodies  >161 publications with Cdc42 and Carcinoma
 Nervous System Diseases Antibodies  >109 publications with Cdc42 and Nervous System Diseases
 Inflammation Antibodies  >95 publications with Cdc42 and Inflammation
 Neoplasm Metastasis Antibodies  >92 publications with Cdc42 and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >89 publications with Cdc42 and Breast Neoplasms
 Necrosis Antibodies  >72 publications with Cdc42 and Necrosis
 Adenocarcinoma Antibodies  >62 publications with Cdc42 and Adenocarcinoma
 Gastrointestinal Diseases Antibodies  >61 publications with Cdc42 and Gastrointestinal Diseases
 Cardiovascular Diseases Antibodies  >55 publications with Cdc42 and Cardiovascular Diseases

Organs/Tissues associated with Cdc42 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >139 publications with Cdc42 and Embryonic Tissue
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