Rat PTPRA Recombinant Protein – Cat# MBS960476

Receptor-Type Tyrosine-Protein Phosphatase Alpha (PTPRA) Rat Recombinant Protein

Name: PTPRA Recombinant Protein; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS960476
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS960476

MBS960476 is a recombinant protein targeting Ptpra. Also known as Recombinant Rat Receptor-type tyrosine-protein phosphatase alpha (Ptpra). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. Ptpra; Lrp More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Receptor-type tyrosine-protein phosphatase alpha (Ptpra), Recombinant Protein

Full Product Name

Recombinant Rat Receptor-type tyrosine-protein phosphatase alpha (Ptpra)

Product Gene Name

Ptpra recombinant protein

Product Synonym Gene Name

Ptpra; Lrp

Product Synonym Names

Receptor-type tyrosine-protein phosphatase alpha; Protein-tyrosine phosphatase alpha; R-PTP-alpha; EC=3.1.3.48

Sequence

N NTTTVSPSLG TTRLIKTSTT ESAKEENKTS NSTSSVISLS VTPTFSPNLT LEPTYVTTVN SSHSDNGTKR AASTESGGTT ISPNGTYGTW LTDNQFTDAR TEPWEGNSSS AATTPETFPP ADETP

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

90,260 Da

Sequence Positions

20-145

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for Q03348

Species

Rattus norvegicus (Rat)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Ptpra recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Ptpra. It may not necessarily be applicable to this product.

NCBI GI #

462549

NCBI GeneID

25167

NCBI Accession #

Q03348.1

UniProt Primary Accession #

Q03348

UniProt Related Accession #

Q03348

NCBI Official Full Name

Receptor-type tyrosine-protein phosphatase alpha

NCBI Official Synonym Full Names

protein tyrosine phosphatase, receptor type, A

NCBI Official Symbol

Ptpra

NCBI Official Synonym Symbols

LRP

UniProt Protein Name

Receptor-type tyrosine-protein phosphatase alpha

Protein Family

Receptor-type tyrosine-protein phosphatase

UniProt Gene Name

Ptpra

UniProt Synonym Gene Names

Lrp; Protein-tyrosine phosphatase alpha; R-PTP-alpha

UniProt Entry Name

PTPRA_RAT

NCBI Protein Information

receptor-type tyrosine-protein phosphatase alpha; R-PTP-alpha; protein tyrosine phosphatase alpha; protein-tyrosine phosphatase alpha

NCBI Summary for Ptpra

member of a family of receptor protein tyrosine phosphatases [RGD, Feb 2006]

UniProt Comments for Ptpra

PTPRA: a receptor protein tyrosine phosphatase (PTP). Contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. Dephosphorylates and activates Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Four alternatively spliced isoforms have been reported.

Protein type: Receptor protein phosphatase, tyrosine; Motility/polarity/chemotaxis; Membrane protein, integral; EC 3.1.3.48

Cellular Component: intracellular membrane-bound organelle; integral to membrane; plasma membrane; receptor complex

Molecular Function: protein binding; protein complex binding; protein tyrosine phosphatase activity

Biological Process: insulin receptor signaling pathway; oligodendrocyte differentiation; positive regulation of oligodendrocyte differentiation; protein amino acid phosphorylation

Research Articles on Ptpra

1. RPTPalpha plays a critical role in HCN channel function via tyrosine dephosphorylation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Ptpra recombinant protein

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
NCAM Signaling For Neurite Out-growth Pathway antibodies	NCAM Signaling For Neurite Out-growth Pathway Diagram
Spinal Cord Injury Pathway antibodies	Spinal Cord Injury Pathway Diagram

Organs/Tissues associated with Ptpra recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>18 publications with Ptpra and Brain
Adipose Tissue Antibodies	>7 publications with Ptpra and Adipose Tissue
Embryonic Tissue Antibodies	>7 publications with Ptpra and Embryonic Tissue
Kidney Antibodies	>6 publications with Ptpra and Kidney
Colon Antibodies	>6 publications with Ptpra and Colon
Lung Antibodies	>5 publications with Ptpra and Lung
Connective Tissue Antibodies	>5 publications with Ptpra and Connective Tissue
Prostate Antibodies	>4 publications with Ptpra and Prostate
Eye Antibodies	>3 publications with Ptpra and Eye
Placenta Antibodies	>2 publications with Ptpra and Placenta