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Potassium Voltage-Gated Channel Subfamily C Member 1 (KCNC1) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS960989

MBS960989 is a recombinant protein targeting Kcnc1. Also known as Recombinant Rat Potassium voltage-gated channel subfamily C member 1 (Kcnc1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Potassium voltage-gated channel subfamily C member 1 (Kcnc1), Recombinant Protein
Full Product Name
Recombinant Rat Potassium voltage-gated channel subfamily C member 1 (Kcnc1)
Product Gene Name
Product Synonym Gene Name
Kcnc1
Product Synonym Names
Recombinant Potassium voltage-gated channel subfamily C member 1 (Kcnc1); Potassium voltage-gated channel subfamily C member 1; NGK2 RAW2 Voltage-gated potassium channel subunit Kv3.1 Voltage-gated potassium channel subunit Kv4
Sequence
MGQGDESERI VINVGGTRHQ TYRSTLRTLP GTRLAWLAEP DAHSHFDYDP RADEFFFDRH PGVFAHILNY YRTGKLHCPA DVCGPLYEEE LAFWGIDETD VEPCCWMTYR QHRDAEEALD SFGGAPLDNS ADDADADGPG DSGDGEDELE MTKRLALSDS PDGRPGGFWR RWQPRIWALF EDPYSSRYAR YVAFASLFFI LVSITTFCLE THERFNPIVN KTEIENVRNG TQVRYYREAE TEAFLTYIEG VCVVWFTFEF LMRVVFCPNK VEFIKNSLNI IDFVAILPFY LEVGLSGLSS KAAKDVLGFL RVVRFVRILR IFKLTRHFVG LRVLGHTLRA STNEFLLLII FLALGVLIFA TMIYYAERIG AQPNDPSASE HTHFKNIPIG FWWAVVTMTT LGYGDMYPQT WSGMLVGALC ALAGVLTIAM PVPVIVNNFG MYYSLAMAKQ KLPKKKKKHI PRPPQLGSPN YCKSVVNSPH HSTQSDTCPL AQEEILEINR ADSKLNGEVA KAALANEDCP HIDQALTPDE GLPFTRSGTR ERYGPCFLLS TGEYACPPGG GMRKDLCKES PVIAKYMPTE AVRVT
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
65,857 Da
Sequence Positions
1-585
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 1; NC_005100.3 (103499689..103541476). Location: 1q22
3D Structure
ModBase 3D Structure for P25122
Species
Rattus norvegicus (Rat)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Kcnc1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Kcnc1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
potassium voltage-gated channel subfamily C member 1
NCBI Official Synonym Full Names
potassium voltage gated channel, Shaw-related subfamily, member 1
NCBI Official Symbol
Kcnc1
NCBI Official Synonym Symbols
Kv4; Kv3.1; KShIIIB; NGK2-KV4
UniProt Protein Name
Potassium voltage-gated channel subfamily C member 1
UniProt Synonym Protein Names
NGK2; RAW2; Voltage-gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv4
UniProt Gene Name
Kcnc1
UniProt Entry Name
KCNC1_RAT
NCBI Protein Information
potassium voltage-gated channel subfamily C member 1; NGK2; RAW2; potassium channel gene 1; voltage-gated potassium channel subunit Kv4; voltage-gated potassium channel subunit Kv3.1

NCBI Summary for Kcnc1

voltage gated potassium channel; functions as a delayed rectifier K+ channel [RGD, Feb 2006]

UniProt Comments for Kcnc1

Kv3.1: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.1/KCNC1 sub-subfamily.

Protein type: Channel, potassium; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: voltage-gated potassium channel complex; cell surface; cell soma; membrane; dendrite; integral to membrane; axolemma

Molecular Function: voltage-gated potassium channel activity; protein binding; kinesin binding; delayed rectifier potassium channel activity

Biological Process: response to toxin; response to light intensity; globus pallidus development; cerebellum development; brain development; protein homooligomerization; response to amine stimulus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with Kcnc1 recombinant protein

Organs/Tissues associated with Kcnc1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >27 publications with Kcnc1 and Brain
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