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Cytochrome P450 11b2, Mitochondrial (CYP11B2) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS962284

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes… More details

$1255 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cytochrome P450 11B2, mitochondrial (Cyp11b2), Recombinant Protein
Full Product Name
Recombinant Rat Cytochrome P450 11B2, mitochondrial (Cyp11b2)
Sequence
GTTATLAPKT LKPFEAIPQY SRNKWLKMIQ ILREQGQENL HLEMHQAFQE LGPIFRHSAG GAQIVSVMLP EDAEKLHQVE SILPRRMHLE PWVAHRELRG LRRGVFLLNG AEWRFNRLKL NPNVLSPKAV QNFVPMVDEV ARDFLEALKK KVRQNARGSL TMDVQQSLFN YTIEASNFAL FGERLGLLGH DLNPGSLKFI HALHSMFKST TQLLFLPRSL TRWTSTQVWK EHFDAWDVIS EYANRCIWKV HQELRLGSSQ TYSGIVAALI TQGALPLDAI KANSMELTAG SVDTTAIPLV MTLFELARNP DVQQALRQET LAAEASIAAN PQKAMSDLPL LRAALKETLR LYPVGGFLER ILNSDLVLQN YHVPAGTLVL LYLYSMGRNP AVFPRPERYM PQRWLERKRS FQHLAFGFGV RQCLGRRLAE VEMLLLLHHM LKTFQVETLR QEDVQMAYRF VLMPSSSPVL TFRPIS
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
58,241 Da
Sequence Positions
35-510, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P30099
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Cyp11b2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cyp11b2 purchase

MBS962284 is a recombinant protein targeting Cyp11b2. Also known as Recombinant Rat Cytochrome P450 11B2, mitochondrial (Cyp11b2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Cyp11b2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Cytochrome P450 11B2, mitochondrial
NCBI Official Synonym Full Names
cytochrome P450, family 11, subfamily b, polypeptide 2
NCBI Official Symbol
Cyp11b2
NCBI Official Synonym Symbols
Cp45as; Cyp11b3; RNCP45AS
UniProt Protein Name
Cytochrome P450 11B2, mitochondrial
UniProt Synonym Protein Names
Aldosterone synthase; CYPXIB2; Cytochrome P450-Aldo-1; Steroid 11-beta-hydroxylase (EC:1.14.15.4, EC:1.14.15.5)
Protein Family
UniProt Gene Name
Cyp11b2
UniProt Synonym Gene Names
Cyp11b-2
NCBI Protein Information
cytochrome P450 11B2, mitochondrial

NCBI Summary for Cyp11b2

steroid 11-beta-monooxygenase that catalyzes steps in the biosynthesis of aldosterone, corticosterone, and 18-hydroxycorticosterone [RGD, Feb 2006]

UniProt Comments for Cyp11b2

Converts 11-deoxycorticosterone into corticosterone, 18-hydroxycorticosterone, and aldosterone. Also can catalyze the conversion of 11-deoxycortisol to cortisol, 18-hydroxycortisol and cortisone.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with Cyp11b2 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >71 publications with Cyp11b2 and Brain
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