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Double C2-Like Domain-Containing Protein Alpha (DOC2A) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS962629

There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which… More details

$1140 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Double C2-like domain-containing protein alpha (Doc2a), Recombinant Protein
Full Product Name
Recombinant Rat Double C2-like domain-containing protein alpha (Doc2a)
Product Gene Name
Sequence
MRGRRGDRMT INIQEHMAIN VCPGPIRPIR QISDYFPRRG PGPEGGGGGR GFGEAPAHLA PLALAPPAAL LGATTPDDGA EVDSYDSDDT TALGTLEFDL LYDQASCMLH CRILRAKGLK PMDFNGLADP YVKLHLLPGA CKANKLKTKT QRNTLNPVWN EELTYSGITD DDITHKVLRI SVCDEDKLSH NEFIGEIRVP LRRLKPSQKK HFNICLERQV PLPSPSSMSA ALRGISCYLK ELEQAEQGPG LLEERGRILL SLSYSSRRHG LLVGIVRCAH LAAMDVNGYS DPYVKTYLRP DVDKKSKHKT CVKKKTLNPE FNEEFFYEME LSTLATKTLE VTVWDYDIGK SNDFIGGVSL GPGARGEAQK HWRDCLHQPD TAVERWHTLT SELPPAAGAL PLA
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
44,590 Da
Sequence Positions
1-403, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P70611
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Doc2a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Doc2a purchase

MBS962629 is a recombinant protein targeting Doc2a. Also known as Recombinant Rat Double C2-like domain-containing protein alpha (Doc2a). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Doc2a. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
double C2-like domain-containing protein alpha
NCBI Official Synonym Full Names
double C2 domain alpha
NCBI Official Symbol
Doc2a
UniProt Protein Name
Double C2-like domain-containing protein alpha
UniProt Gene Name
Doc2a
UniProt Synonym Gene Names
Doc2-alpha
NCBI Protein Information
double C2-like domain-containing protein alpha

NCBI Summary for Doc2a

mouse homolog is a putative Ca2+ and phospholipid binding protein; may be involved in Ca2(+)-dependent exocytosis at the synapse [RGD, Feb 2006]

UniProt Comments for Doc2a

Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca2+-dependent secretory lysosome exocytosis in mast cells ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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