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Protein Wnt-7b (WNT7B) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS963405

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters More details

$285 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Protein Wnt-7b (WNT7B), Recombinant Protein
Full Product Name
Recombinant Human Protein Wnt-7b (WNT7B)
Product Gene Name
WNT7B recombinant protein
Product Synonym Gene Name
WNT7B
Product Synonym Names
Recombinant Protein Wnt-7b (WNT7B); Protein Wnt-7b
Sequence
ALSSVVALGA NIICNKIPGL APRQRAICQS RPDAIIVIGE GAQMGINECQ YQFRFGRWNC SALGEKTVFG QELRVGSREA AFTYAITAAG VAHAVTAACS QGNLSNCGCD REKQGYYNQA EGWKWGGCSA DVRYGIDFSR RFVDAREIKK NARRLMNLHN NEAGRKVLED RMQLECKCHG VSGSCTTKTC WTTLPKFREV GHLLKEKYNA AVQVEVVRAS RLRQPTFLRI KQLRSYQKPM ETDLVYIEKS PNYCEEDAAT GSVGTQGRLC NRTSPGADGC DTMCCGRGYN THQYTKVWQC NCKFHWCCFV KCNTCSERTE VFTCK
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
40.2 kDa
Sequence Positions
25-349aa; Full Length of Mature Protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 22; NC_000022.10 (46316246..46373008, complement). Location: 22q13
OMIM
601967
3D Structure
ModBase 3D Structure for P56706
Species
Homo sapiens (Human)

Product Categories/Family for WNT7B recombinant protein

Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

SDS-PAGE of WNT7B recombinant protein

Human WNT7B Recombinant Protein – Cat# MBS963405

Other Notes

Small volumes of WNT7B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WNT7B purchase

MBS963405 is a recombinant protein targeting WNT7B. Also known as Recombinant Human Protein Wnt-7b (WNT7B). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for WNT7B. It may not necessarily be applicable to this product.

NCBI GI #
17505193
NCBI GeneID
7477
NCBI Accession #
NP_478679.1
UniProt Primary Accession #
P56706
UniProt Secondary Accession #
Q96Q12; B8A596
UniProt Related Accession #
P56706
GenBank Nucleotide #
NM_058238.2
NCBI Official Full Name
protein Wnt-7b
NCBI Official Synonym Full Names
wingless-type MMTV integration site family, member 7B
NCBI Official Symbol
WNT7B
UniProt Protein Name
Protein Wnt-7b
Protein Family
Protein
UniProt Gene Name
WNT7B
UniProt Entry Name
WNT7B_HUMAN
NCBI Protein Information
protein Wnt-7b

NCBI Summary for WNT7B

This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among members of the human WNT family, this gene product is most similar to WNT7A protein. [provided by RefSeq, Oct 2008]
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UniProt Comments for WNT7B

WNT7B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Belongs to the Wnt family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 22q13

Cellular Component: proteinaceous extracellular matrix; extracellular space; Golgi lumen; endoplasmic reticulum lumen; extracellular region; plasma membrane

Molecular Function: frizzled binding

Biological Process: oxygen homeostasis; response to glucocorticoid stimulus; positive regulation of JNK cascade; Wnt receptor signaling pathway through beta-catenin; forebrain regionalization; anatomical structure regression; activation of JNK activity; neuron differentiation; cellular metabolic process; central nervous system vasculogenesis; homeostatic process; fibroblast proliferation; positive regulation of cell proliferation; regulation of cell projection size; synapse organization and biogenesis; establishment and/or maintenance of polarity of embryonic epithelium; Wnt receptor signaling pathway; cell fate commitment; in utero embryonic development; odontogenesis of dentine-containing teeth; positive regulation of osteoblast differentiation; negative regulation of smoothened signaling pathway; embryonic organ development; smooth muscle cell differentiation; neurite morphogenesis; lung development
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Research Articles on WNT7B

1. Pdgf signaling potentiates Wnt2-Wnt7b signaling to promote high levels of Wnt activity in mesenchymal progenitors that is required for proper development of endoderm-derived organs, such as the lung

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with WNT7B recombinant protein

 Products by Pathway  Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 DNA Damage Response (only ATM Dependent) Pathway antibodies  DNA Damage Response (only ATM Dependent) Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram

Diseases associated with WNT7B recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >26 publications with WNT7B and Neoplasms
 Breast Neoplasms Antibodies  >11 publications with WNT7B and Breast Neoplasms
 Disease Models, Animal Antibodies  >9 publications with WNT7B and Disease Models, Animal
 Lung Diseases Antibodies  >5 publications with WNT7B and Lung Diseases
 Bone Diseases Antibodies  >5 publications with WNT7B and Bone Diseases
 Necrosis Antibodies  >5 publications with WNT7B and Necrosis
 Stomach Neoplasms Antibodies  >5 publications with WNT7B and Stomach Neoplasms
 Fibrosis Antibodies  >5 publications with WNT7B and Fibrosis
 Inflammation Antibodies  >4 publications with WNT7B and Inflammation
 Pancreatic Neoplasms Antibodies  >4 publications with WNT7B and Pancreatic Neoplasms

Organs/Tissues associated with WNT7B recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >26 publications with WNT7B and Embryonic Tissue
 Bone Antibodies  >25 publications with WNT7B and Bone
 Brain Antibodies  >25 publications with WNT7B and Brain
 Lung Antibodies  >19 publications with WNT7B and Lung
 Kidney Antibodies  >14 publications with WNT7B and Kidney
 Eye Antibodies  >11 publications with WNT7B and Eye
 Liver Antibodies  >6 publications with WNT7B and Liver
 Heart Antibodies  >5 publications with WNT7B and Heart
 Pancreas Antibodies  >3 publications with WNT7B and Pancreas
 Skin Antibodies  >3 publications with WNT7B and Skin
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