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Inositol Monophosphatase 1 (IMPA1) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS963607

This gene encodes an enyzme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second… More details

$960 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Inositol monophosphatase 1 (Impa1), Recombinant Protein
Full Product Name
Recombinant Rat Inositol monophosphatase 1 (Impa1)
Product Gene Name
Impa1 recombinant protein
Sequence
MADPWQECMD YAVILARQAG EMIREALKNK MDVMIKSSPA DLVTVTDQKV EKMLMSSIKE KYPYHSFIGE ESVASGEKTV FTEQPTWIID PIDGTTNFVH RFPFVAVSIG FVVNKEMEFG VVYSCVEDKM YTGRKGKGAF CNGQKLRVSQ QEDITKSLLV TELGSSRKPE TLRIVLSNME RLCSIPIHGI RSVGTAAVNM CLVATGGADA YYEMGIHCWD MAGAGIIVIE AGGVLLDVTG GPFDLMSRRI IAASNIALAE RIAKELEIIP LQRDDES
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
30,511 Da
Sequence Positions
1-277, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P97697
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Impa1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Impa1 purchase

MBS963607 is a recombinant protein targeting Impa1. Also known as Recombinant Rat Inositol monophosphatase 1 (Impa1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Impa1. It may not necessarily be applicable to this product.

NCBI GI #
14091736
NCBI GeneID
83523
NCBI Accession #
NP_114446.1
UniProt Primary Accession #
P97697
UniProt Related Accession #
P97697
GenBank Nucleotide #
NM_032057.1
NCBI Official Full Name
inositol monophosphatase 1
NCBI Official Synonym Full Names
inositol monophosphatase 1
NCBI Official Symbol
Impa1
NCBI Official Synonym Symbols
Impa1-L
UniProt Protein Name
Inositol monophosphatase 1
UniProt Synonym Protein Names
D-galactose 1-phosphate phosphatase
Protein Family
Inositol monophosphatase
UniProt Gene Name
Impa1
UniProt Synonym Gene Names
Imp; IMP 1; IMPase 1
NCBI Protein Information
inositol monophosphatase 1

NCBI Summary for Impa1

enzyme which controls the levels of brain inositol [RGD, Feb 2006]

UniProt Comments for Impa1

Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo-inositol 1,3-diphosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates (). Is equally active with myo-inositol monophosphate and D-galactose 1-phosphate.
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Research Articles on Impa1

1. local synthesis of IMPA1 is required for neurotrophin-dependent axon growth; selective regulation of IMPA1 levels in axons may provide a target for the development of new therapeutic strategies for specific neurological and psychiatric diseases

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Impa1 recombinant protein

 Reference Product  PubMed Publications
 Impa2 recombinant protein  >13 publications with Impa1 and Impa2
 Isyna1 recombinant protein  >2 publications with Impa1 and Isyna1
 Plcd1 recombinant protein  >1 publications with Impa1 and Plcd1

Pathways associated with Impa1 recombinant protein

 Products by Pathway  Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway antibodies  Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway Diagram
 Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway antibodies  Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Phosphatidylinositol Signaling System Pathway antibodies  Phosphatidylinositol Signaling System Pathway Diagram
 Phosphatidylinositol Signaling System Pathway antibodies  Phosphatidylinositol Signaling System Pathway Diagram
 Synthesis Of IP2, IP, And Ins In The Cytosol Pathway antibodies  Synthesis Of IP2, IP, And Ins In The Cytosol Pathway Diagram

Diseases associated with Impa1 recombinant protein

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >4 publications with Impa1 and Disease Models, Animal
 Seizures Antibodies  >4 publications with Impa1 and Seizures
 Brain Diseases Antibodies  >3 publications with Impa1 and Brain Diseases
 Depressive Disorder Antibodies  >2 publications with Impa1 and Depressive Disorder

Organs/Tissues associated with Impa1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >14 publications with Impa1 and Brain
 Kidney Antibodies  >4 publications with Impa1 and Kidney
 Muscle Antibodies  >3 publications with Impa1 and Muscle
 Lung Antibodies  >1 publications with Impa1 and Lung
 Heart Antibodies  >1 publications with Impa1 and Heart
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