Rat SYN1 Recombinant Protein – Cat# MBS9020216

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Synapsin-1 (SYN1) Rat Recombinant Protein

Name: SYN1 Recombinant Protein; Synapsin-1; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS9020216
Price: 315 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9020216

MBS9020216 is a recombinant protein targeting Syn1. Also known as Recombinant Rat Synapsin-1 (Syn1), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$315 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Synapsin-1 (Syn1), Recombinant Protein

Full Product Name

Recombinant Rat Synapsin-1 (Syn1), partial

Product Gene Name

Syn1 recombinant protein

Product Synonym Names

Synapsin I

Sequence

ARVLLVIDEP HTDWAKYFKG KKIHGEIDIK VEQAEFSDLN LVAHANGGFS VDMEVLRNGV KVVRSLKPDF VLIRQHAFSM ARNGDYRSLV IGLQYAGIPS VNSLHSVYNF CDKPWVFAQM VRLHKKLGTE EFPLIDQTFY PNHKEMLSST TYPVVVKMGH AHSGMGKVKV DNQHDFQDIA SVVALTKTYA TAEPFIDAKY DVRVQKIGQN YKAYMRTSVS GNWKTNTGSA MLEQIAMSDR YKLWVDTCSE IFGGLDICAV EALHGKDGRD HIIEVVGSSM PLIGDHQDED KQLIVELVVN KMTQALPR

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Liquid or Lyophilized powder
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8

Purity/Purification

Greater than 90% as determined by SDS-PAGE. (lot specific)

Preparation and Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 degree C/-80 degree C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Molecular Weight

69,910 Da

Sequence Positions

113-420aa; Partial

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for P09951

Species

Rattus norvegicus (Rat)

Tag

C-terminal 6xHis-tagged

Research Area

Others

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Product References and Citations for Syn1 recombinant protein

"Fusion of lamellar body with plasma membrane is driven by the dual action of annexin II tetramer and arachidonic acid."Chattopadhyay S., Sun P., Wang P., Abonyo B., Cross N.L., Liu L.J Biol Chem 278:39675-39683(2003)

Other Notes

Small volumes of Syn1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Syn1. It may not necessarily be applicable to this product.

NCBI GI #

160707907

NCBI GeneID

24949

NCBI Accession #

NP_001104252.1

UniProt Primary Accession #

P09951

UniProt Secondary Accession #

Q9WUX7

UniProt Related Accession #

P09951

GenBank Nucleotide #

NM_001110782.2

NCBI Official Full Name

synapsin-1 isoform b

NCBI Official Synonym Full Names

synapsin I

NCBI Official Symbol

Syn1

UniProt Protein Name

Synapsin-1

UniProt Synonym Protein Names

Synapsin I

Protein Family

Sister chromatid cohesion 1 protein

UniProt Gene Name

Syn1

UniProt Entry Name

SYN1_RAT

NCBI Protein Information

synapsin-1; synapsin 1

NCBI Summary for Syn1

may act as an anchoring protein by linking the vesicle phospholipid layer and the cytoskeleton in neuronal presynaptic terminals; may play a role in neurotransmitter release [RGD, Feb 2006]

UniProt Comments for Syn1

SYN1: neuronal phosphoprotein which associates with the cytoplasmic surface of synaptic vesicles and binds to the cytoskeleton. May function in the regulation of neurotransmitter release and of axonogenesis and synaptogenesis. Mutations may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Two differentially spiced isoforms have been reported.

Protein type: Vesicle

Cellular Component: Golgi apparatus; synaptic vesicle membrane; cell; dendrite; postsynaptic density; intracellular organelle; terminal button; synaptonemal complex; cytosol; synaptic vesicle; axon; presynaptic active zone; synapse; cell junction

Molecular Function: protein binding; actin binding; calcium-dependent protein binding; catalytic activity; protein kinase binding; ATP binding

Biological Process: metabolic process; neurotransmitter secretion

Research Articles on Syn1

1. rSynI(1.0)-minCMV drives robust and neuron-specific transgene expression throughout the CNS and is therefore useful for viral vector-mediated neuron-specific gene delivery and generation of neuron-specific transgenic animals.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Syn1 recombinant protein

Reference Product	PubMed Publications
Syn2 recombinant protein	>17 publications with Syn1 and Syn2
Syn3 recombinant protein	>8 publications with Syn1 and Syn3
Syp recombinant protein	>5 publications with Syn1 and Syp

Pathways associated with Syn1 recombinant protein

Products by Pathway	Pathway Diagram
CFTR Activity In The Plasma Membrane Pathway antibodies	CFTR Activity In The Plasma Membrane Pathway Diagram

Diseases associated with Syn1 recombinant protein

Disease Name	Pubmed Publications
Mental Disorders Antibodies	>14 publications with Syn1 and Mental Disorders
Brain Diseases Antibodies	>12 publications with Syn1 and Brain Diseases
Central Nervous System Diseases Antibodies	>10 publications with Syn1 and Central Nervous System Diseases
Cognition Disorders Antibodies	>4 publications with Syn1 and Cognition Disorders
Neurobehavioral Manifestations Antibodies	>4 publications with Syn1 and Neurobehavioral Manifestations
Necrosis Antibodies	>4 publications with Syn1 and Necrosis
Seizures Antibodies	>3 publications with Syn1 and Seizures
Learning Disorders Antibodies	>3 publications with Syn1 and Learning Disorders
Chromosome Aberrations Antibodies	>3 publications with Syn1 and Chromosome Aberrations
Child Behavior Disorders Antibodies	>3 publications with Syn1 and Child Behavior Disorders

Organs/Tissues associated with Syn1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>31 publications with Syn1 and Brain
Eye Antibodies	>2 publications with Syn1 and Eye