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Diacylglycerol Kinase Theta (DGKQ) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS964274

This protein contains three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain. It is localized in the speckle domains of the nucleus, and mediates the regeneration of phosphatidylinositol… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Diacylglycerol kinase theta (DGKQ), Recombinant Protein
Full Product Name
Recombinant Human Diacylglycerol kinase theta (DGKQ) , partial
Product Gene Name
DGKQ recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
101,155 Da
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
601207
3D Structure
ModBase 3D Structure for P52824
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of DGKQ recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DGKQ purchase

MBS964274 is a recombinant protein targeting DGKQ. Also known as Recombinant Human Diacylglycerol kinase theta (DGKQ) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for DGKQ. It may not necessarily be applicable to this product.

NCBI GI #
40806175
NCBI GeneID
1609
NCBI Accession #
NP_001338.2
UniProt Primary Accession #
P52824
UniProt Secondary Accession #
Q6P3W4
UniProt Related Accession #
P52824
GenBank Nucleotide #
NM_001347.3
NCBI Official Full Name
diacylglycerol kinase theta
NCBI Official Synonym Full Names
diacylglycerol kinase theta
NCBI Official Symbol
DGKQ
NCBI Official Synonym Symbols
DAGK; DAGK4; DAGK7
UniProt Protein Name
Diacylglycerol kinase theta
UniProt Synonym Protein Names
Diglyceride kinase theta; DGK-theta
Protein Family
Diacylglycerol kinase
UniProt Gene Name
DGKQ
UniProt Synonym Gene Names
DAGK4; DAG kinase theta; DGK-theta
NCBI Protein Information
diacylglycerol kinase theta

NCBI Summary for DGKQ

The protein encoded by this gene contains three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain. It is localized in the speckle domains of the nucleus, and mediates the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. [provided by RefSeq, Jul 2008]
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UniProt Comments for DGKQ

Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). May regulate the activity of protein kinase C by controlling the balance between these two signaling lipids. Activated in the nucleus in response to alpha-thrombin and nerve growth factor (). May be involved in cAMP-induced activation of NR5A1 and subsequent steroidogenic gene transcription by delivering PA as ligand for NR5A1. Acts synergistically with NR5A1 on CYP17 transcriptional activity.
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Research Articles on DGKQ

1. these data demonstrate that DGKtheta; plays an important role in steroid hormone production in human adrenocortical cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with DGKQ recombinant protein

 Products by Pathway  Pathway Diagram
 Effects Of PIP2 Hydrolysis Pathway antibodies  Effects Of PIP2 Hydrolysis Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Phosphatidylinositol Signaling System Pathway antibodies  Phosphatidylinositol Signaling System Pathway Diagram

Diseases associated with DGKQ recombinant protein

 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >1 publications with DGKQ and Immune System Diseases
 Heart Diseases Antibodies  >1 publications with DGKQ and Heart Diseases
 Sjogren's Syndrome Antibodies  >1 publications with DGKQ and Sjogren's Syndrome

Organs/Tissues associated with DGKQ recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with DGKQ and Nerve
 Brain Antibodies  >1 publications with DGKQ and Brain
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