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Nociceptin Receptor (OPRL1) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS964917

MBS964917 is a recombinant protein targeting Oprl1. Also known as Recombinant Rat Nociceptin receptor (Oprl1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Nociceptin receptor (Oprl1), Recombinant Protein
Full Product Name
Recombinant Rat Nociceptin receptor (Oprl1)
Product Gene Name
Oprl1 recombinant protein
Product Synonym Gene Name
Oprl1; Oor, Oprl
Product Synonym Names
Recombinant Nociceptin receptor (Oprl1); Nociceptin receptor; Kappa-type 3 opioid receptor; KOR-3 Orphanin FQ receptor ROR-C XOR1
Sequence
MESLFPAPYW EVLYGSHFQG NLSLLNETVP HHLLLNASHS AFLPLGLKVT IVGLYLAVCI GGLLGNCLVM YVILRHTKMK TATNIYIFNL ALADTLVLLT LPFQGTDILL GFWPFGNALC KTVIAIDYYN MFTSTFTLTA MSVDRYVAIC HPIRALDVRT SSKAQAVNVA IWALASVVGV PVAIMGSAQV EDEEIECLVE IPAPQDYWGP VFAICIFLFS FIIPVLIISV CYSLMIRRLR GVRLLSGSRE KDRNLRRITR LVLVVVAVFV GCWTPVQVFV LVQGLGVQPG SETAVAILRF CTALGYVNSC LNPILYAFLD ENFKACFRKF CCASSLHREM QVSDRVRSIA KDVGLGCKTS ETVPRPA
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
40,523 Da
Sequence Positions
1-367
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 3; NC_005102.3 (180934268..180940194). Location: 3q43
3D Structure
ModBase 3D Structure for P35370
Species
Rattus norvegicus (Rat)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Oprl1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Oprl1. It may not necessarily be applicable to this product.

NCBI GI #
13928772
NCBI GeneID
29256
NCBI Accession #
NP_113757.1
UniProt Primary Accession #
P35370
UniProt Secondary Accession #
Q791R4
UniProt Related Accession #
P35370
GenBank Nucleotide #
NM_031569.3
NCBI Official Full Name
nociceptin receptor
NCBI Official Synonym Full Names
opiate receptor-like 1
NCBI Official Symbol
Oprl1
NCBI Official Synonym Symbols
KOR3; OFQR; ORL1; Oprl; XOR1; KOR-3; LC132; MOR-C
UniProt Protein Name
Nociceptin receptor
UniProt Synonym Protein Names
Kappa-type 3 opioid receptor; KOR-3; Orphanin FQ receptor; ROR-C; XOR1
Protein Family
Nociceptin receptor
UniProt Gene Name
Oprl1
UniProt Synonym Gene Names
Oor; Oprl; KOR-3
UniProt Entry Name
OPRX_RAT
NCBI Protein Information
nociceptin receptor; ROR-C; peptide receptor; orphanin FQ receptor; opioid receptor-like 1; orphanin FQ receptor-a; orphanin FQ receptor-b; orphanin FQ receptor-e; nociceptin receptor ORL1; kappa-type 3 opioid receptor; seven transmembrane G protein-coupled receptor

NCBI Summary for Oprl1

orphan G-protein coupled receptor; may be a member of the opioid receptor gene family [RGD, Feb 2006]

UniProt Comments for Oprl1

KOR-3: Receptor for the neuropeptide nociceptin/orphanin FQ. Has a potential role in modulating a number of brain functions, including instinctive behaviors and emotions. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1

Cellular Component: neuron projection; integral to plasma membrane; cytoplasmic membrane-bound vesicle; integral to membrane

Molecular Function: G-protein coupled receptor activity; neuropeptide binding; nociceptin/orphanin-FQ receptor activity

Biological Process: synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; elevation of cytosolic calcium ion concentration; neuropeptide signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; sensory perception of pain
Show more

Research Articles on Oprl1

1. stress can affect N/OFQ expression and that glucocorticoids may constitute hormonal mediators of this complex interplay.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Oprl1 recombinant protein

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Peptide GPCRs Pathway antibodies  Peptide GPCRs Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with Oprl1 recombinant protein

 Disease Name  Pubmed Publications
 Substance-Related Disorders Antibodies  >4 publications with Oprl1 and Substance-Related Disorders
 Opioid-Related Disorders Antibodies  >2 publications with Oprl1 and Opioid-Related Disorders
 Pain Antibodies  >1 publications with Oprl1 and Pain

Organs/Tissues associated with Oprl1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with Oprl1 and Brain
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