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Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Pig Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS965016

MBS965016 is a recombinant protein targeting ALOX5AP. Also known as Recombinant Pig Arachidonate 5-lipoxygenase-activating protein (ALOX5AP). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Arachidonate 5-lipoxygenase-activating protein (ALOX5AP), Recombinant Protein
Full Product Name
Recombinant Pig Arachidonate 5-lipoxygenase-activating protein (ALOX5AP)
Product Synonym Gene Name
ALOX5AP; FLAP
Product Synonym Names
Recombinant Arachidonate 5-lipoxygenase-activating protein (ALOX5AP); Arachidonate 5-lipoxygenase-activating protein; FLAP MK-886-binding protein
Sequence
MDQEAMGNIV LLAIVTLISV VQNAFFAHKV EHESKTHNGR SFQRTGTPAF ERVYTANQNC VDAYPTFLVV LWSAGLFCSQ VPAAFAGLMY LFVRQKYFVG YLGERTQSTP GYIFGKRIIL FLFLMSLAGI FNYFLILFFG SDFENYIKTI TTT
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
17,345 Da
Sequence Positions
1-153
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P30356
Species
Sus scrofa (Pig)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ALOX5AP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ALOX5AP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
NCBI Official Full Name
Arachidonate 5-lipoxygenase-activating protein
UniProt Protein Name
Arachidonate 5-lipoxygenase-activating protein
UniProt Synonym Protein Names
FLAP; MK-886-binding protein
UniProt Gene Name
ALOX5AP
UniProt Synonym Gene Names
FLAP
UniProt Entry Name
AL5AP_PIG

UniProt Comments for ALOX5AP

Function: Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes

By similarity. unstructured

By similarity.

Subunit structure: Homotrimer. Interacts with LTC4S and ALOX5

By similarity.

Subcellular location: Nucleus membrane; Multi-pass membrane protein

By similarity. Endoplasmic reticulum membrane; Multi-pass membrane protein

By similarity.

Domain: The C-terminal part after residue 140 is mostly disordered

By similarity.

Sequence similarities: Belongs to the MAPEG family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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