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CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2,3-Sialyltransferase 1 (ST3GAL1) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS965851

MBS965851 is a recombinant protein targeting St3gal1. Also known as Recombinant Mouse CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (St3gal1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (St3gal1), Recombinant Protein
Full Product Name
Recombinant Mouse CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (St3gal1)
Product Gene Name
St3gal1 recombinant protein
Product Synonym Gene Name
St3gal1; Siat4; Siat4a
Product Synonym Names
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; Alpha 2,3-ST 1; Beta-galactoside alpha-2,3-sialyltransferase 1; EC=2.4.99.4; Gal-NAc6S; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; ST3Gal I; ST3GalI; ST3GalA.1; ST3O; Sialyltr
Sequence
MRRKTLKYLT FFLLFIFLTS FVLNYSNTGV PSAWFPKQML LELSENFRRF IKSQPCTCRH CISQDKVSYW FDQRFNKTMQ PLLTVHNALM EEDTYRWWLR LQRERKPNNL SDTVKELFRL VPGNVDPMLN KRLVGCRRCA VVGNSGNLKD SSYGPEIDSH DFVLRMNKAP TVGFEADVGS RTTHHLVYPE SFRELGENVN MVLVPFKTTD LQWVISATTT GTITHTYVPV PPKIKVKQEK ILIYHPAFIK YVFDNWLQGH GRYPSTGILS IIFSIHICDE VDLYGFGADS KGNWHHYWEN NPSAGAFRKT GVHDGDFEYN ITTTLAAINK IRIFKGR
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
39,073 Da
Sequence Positions
1-337
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P54751
Species
Mus musculus (Mouse)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of St3gal1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for St3gal1. It may not necessarily be applicable to this product.

NCBI GI #
6677957
NCBI GeneID
20442
NCBI Accession #
NP_033203.1
UniProt Primary Accession #
P54751
UniProt Secondary Accession #
Q11202
UniProt Related Accession #
P54751
GenBank Nucleotide #
NM_009177.4
NCBI Official Full Name
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
NCBI Official Synonym Full Names
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
NCBI Official Symbol
St3gal1
NCBI Official Synonym Symbols
Siat4; Siat4a; ST3GalI; AI467004; St3gal-1; 5330418N22Rik
UniProt Protein Name
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
UniProt Synonym Protein Names
Gal-NAc6S; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; ST3Gal I; ST3GalI; ST3GalA.1; ST3O; Sialyltransferase 4A; SIAT4-A
Protein Family
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase
UniProt Gene Name
St3gal1
UniProt Synonym Gene Names
Siat4; Siat4a; Alpha 2,3-ST 1; Beta-galactoside alpha-2,3-sialyltransferase 1; ST3GalI; SIAT4-A
UniProt Entry Name
SIA4A_MOUSE
NCBI Protein Information
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; ST3O; SIAT4-A; ST3Gal I; ST3GalA.1; gal-NAc6S; alpha 2,3-ST 1; ST3GAL-I sialyltransferase; Gal beta1,3 GalNAc alpha2,3 sialyltransferase; beta-galactoside alpha-2,3-sialyltransferase 1; gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; sialyltransferase 4A (beta-galactoside alpha-2,3-sialytransferase); sialyltransferase 4A (beta-galactosidase alpha-2,3-sialytransferase); CMP-N-acetylneuraminate: [beta-galactosidase alpha-2,3] sialytransferase

UniProt Comments for St3gal1

ST3GAL1: It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on sugar chains O- linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. Belongs to the glycosyltransferase 29 family.

Protein type: Glycan Metabolism - keratan sulfate biosynthesis; Glycan Metabolism - O-glycan biosynthesis; EC 2.4.99.4; Membrane protein, integral; Transferase; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; Glycan Metabolism - glycosphingolipid biosynthesis - globo series

Cellular Component: Golgi apparatus; membrane; integral to membrane; extracellular region; integral to Golgi membrane

Molecular Function: transferase activity; transferase activity, transferring glycosyl groups; sialyltransferase activity; beta-galactoside alpha-2,3-sialyltransferase activity

Biological Process: protein amino acid glycosylation; protein amino acid phosphorylation
Show more

Research Articles on St3gal1

1. tryptophan and cysteine residues conserved in ST3Gal I are critical for its activity

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with St3gal1 recombinant protein

 Products by Pathway  Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway antibodies  Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Glycogen Storage Diseases Pathway antibodies  Glycogen Storage Diseases Pathway Diagram
 Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway antibodies  Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway Diagram
 Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway antibodies  Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Glycosphingolipid Biosynthesis - Ganglio Series Pathway antibodies  Glycosphingolipid Biosynthesis - Ganglio Series Pathway Diagram
 Glycosphingolipid Biosynthesis - Ganglio Series Pathway antibodies  Glycosphingolipid Biosynthesis - Ganglio Series Pathway Diagram
 Glycosphingolipid Biosynthesis - Globo Series Pathway antibodies  Glycosphingolipid Biosynthesis - Globo Series Pathway Diagram

Diseases associated with St3gal1 recombinant protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with St3gal1 and Inflammation
 Necrosis Antibodies  >1 publications with St3gal1 and Necrosis

Organs/Tissues associated with St3gal1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with St3gal1 and Brain
 Blood Antibodies  >1 publications with St3gal1 and Blood
 Joint Antibodies  >1 publications with St3gal1 and Joint
 Bone Marrow Antibodies  >1 publications with St3gal1 and Bone Marrow
 Muscle Antibodies  >1 publications with St3gal1 and Muscle
 Bone Antibodies  >1 publications with St3gal1 and Bone
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