Human ARHGAP10 Recombinant Protein – Cat# MBS966433

Rho Gtpase-Activating Protein 10 (ARHGAP10) Human Recombinant Protein

Name: ARHGAP10 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS966433
Price: 1665 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS966433

MBS966433 is a recombinant protein targeting ARHGAP10. Also known as Recombinant Human Rho GTPase-activating protein 10 (ARHGAP10). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1665 / 0.02 mg (E-Coli) +2 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Rho GTPase-activating protein 10 (ARHGAP10), Recombinant Protein

Full Product Name

Recombinant Human Rho GTPase-activating protein 10 (ARHGAP10)

Product Gene Name

ARHGAP10 recombinant protein

Sequence

MGLQPLEFSD CYLDSPWFRE RIRAHEAELE RTNKFIKELI KDGKNLIAAT KSLSVAQRKF AHSLRDFKFE FIGDAVTDDE RCIDASLREF SNFLKNLEEQ REIMALSVTE TLIKPLEKFR KEQLGAVKEE KKKFDKETEK NYSLIDKHLN LSAKKKDSHL QEADIQVEQN RQHFYELSLE YVCKLQEIQE RKKFEFVEPM LSFFQGMFTF YHQGHELAKD FNHYKMELQI NIQNTRNRFE GTRSEVEELM NKIRQNPKDH KRASQFTAEG YLYVQEKRPA PFGSSWVKHY CMYRKAAKKF NMIPFEHRSG GKLGDGEVFF LKECTKRHTD SIDRRFCFDI EAADRPGVSL TMQAFSEEER KQWLEALGGK EALSHSFNTA IIPRPEGNAQ LDKMGFTIIR KCISAVETRG INDQGLYRVV GVSSKVQRLL SMLMDVKTCN EVDLENSADW EVKTITSALK QYLRSLPEPL MTYELHGDFI VPAKSGSPES RVNAIHFLVH KLPEKNKEML DILVKHLTNV SNHSKQNLMT VANLGVVFGP TLMRPQEETV AALMDLKFQN IVVEILIENH EKIFRTPPDT TFPEPTCLSA SPPNAPPRQS KRQGQRTKRP VAVYNLCLEL EDGDNPYPSK EDTPTSSLDS LSSPSPVTTA VPGPPGPDKN HLLADGGSFG DWASTIPGQT RSSMVQWLNP QSPTTTSSNS AVTPLSPGSS PFPFSPPATV ADKPPESIRS RKARAVYPCE AEHSSELSFE IGAIFEDVQT SREPGWLEGT LNGKRGLIPQ NYVKLL

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

89,375 Da

Sequence Positions

1-786, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

609746

3D Structure

ModBase 3D Structure for A1A4S6

Species

Human

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ARHGAP10 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ARHGAP10. It may not necessarily be applicable to this product.

NCBI GI #

50843948

NCBI GeneID

79658

NCBI Accession #

NP_078881.3

UniProt Primary Accession #

A1A4S6

UniProt Secondary Accession #

Q2VPC4; Q2VPC5; Q96EV3; Q96S75; A1L0S5

UniProt Related Accession #

A1A4S6

GenBank Nucleotide #

NM_024605.3

NCBI Official Full Name

rho GTPase-activating protein 10

NCBI Official Synonym Full Names

Rho GTPase activating protein 10

NCBI Official Symbol

ARHGAP10

NCBI Official Synonym Symbols

GRAF2; PSGAP; PS-GAP

UniProt Protein Name

Rho GTPase-activating protein 10

UniProt Synonym Protein Names

GTPase regulator associated with focal adhesion kinase 2; Graf-related protein 2; Rho-type GTPase-activating protein 10

Protein Family

Rho GTPase-activating protein

UniProt Gene Name

ARHGAP10

UniProt Synonym Gene Names

GRAF2

NCBI Protein Information

rho GTPase-activating protein 10

UniProt Comments for ARHGAP10

GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death ().

Research Articles on ARHGAP10

1. ARHGAP10 may serve as a tumor suppressor through inactivating Cdc42, as well as inhibiting cell cycle, replication and BER pathways.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ARHGAP10 recombinant protein

Reference Product	PubMed Publications
CDC42 recombinant protein	>8 publications with ARHGAP10 and CDC42
RHOA recombinant protein	>5 publications with ARHGAP10 and RHOA
CTNNB1 recombinant protein	>1 publications with ARHGAP10 and CTNNB1

Pathways associated with ARHGAP10 recombinant protein

Products by Pathway	Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
Regulation Of Apoptosis Pathway antibodies	Regulation Of Apoptosis Pathway Diagram
Regulation Of PAK-2p34 Activity By PS-GAP/RHG10 Pathway antibodies	Regulation Of PAK-2p34 Activity By PS-GAP/RHG10 Pathway Diagram
Rho GTPase Cycle Pathway antibodies	Rho GTPase Cycle Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By Rho GTPases Pathway antibodies	Signaling By Rho GTPases Pathway Diagram

Diseases associated with ARHGAP10 recombinant protein

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>1 publications with ARHGAP10 and Breast Neoplasms

Organs/Tissues associated with ARHGAP10 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3 publications with ARHGAP10 and Brain
Connective Tissue Antibodies	>1 publications with ARHGAP10 and Connective Tissue
Bone Antibodies	>1 publications with ARHGAP10 and Bone
Muscle Antibodies	>1 publications with ARHGAP10 and Muscle
Spleen Antibodies	>1 publications with ARHGAP10 and Spleen
Eye Antibodies	>1 publications with ARHGAP10 and Eye
Lung Antibodies	>1 publications with ARHGAP10 and Lung
Kidney Antibodies	>1 publications with ARHGAP10 and Kidney