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Natriuretic Peptides A (NPPA) Horse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS966700

This protein belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is… More details

$625 / 0.05 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Natriuretic peptides A (NPPA), Recombinant Protein
Full Product Name
Recombinant Horse Natriuretic peptides A (NPPA)
Product Gene Name
Product Synonym Gene Name
NPPA
Product Synonym Names
Recombinant Natriuretic peptides A (NPPA); Natriuretic peptides A; Prepronatriodilatin Cleaved into the following chain: 1. Atrial natriuretic factor; 2. ANF; Atrial natriuretic peptide; ANP
Sequence
SLRRSSC FGGRMDRIGA QSGLGCNSFR Y
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
16,825 Da
Sequence Positions
124-151aa; Cytoplasmic domain
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 2; NC_009145.2 (39805518..39806900). Location: chromosome: 2
3D Structure
ModBase 3D Structure for P27104
Species
Equus caballus (Horse)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NPPA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NPPA purchase

MBS966700 is a recombinant protein targeting NPPA. Also known as Recombinant Horse Natriuretic peptides A (NPPA). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for NPPA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
natriuretic peptides A preproprotein
NCBI Official Symbol
NPPA
UniProt Protein Name
Natriuretic peptides A
UniProt Synonym Protein Names
PrepronatriodilatinCleaved into the following chain:Atrial natriuretic factor; ANF; Alternative name(s):; Atrial natriuretic peptide
UniProt Gene Name
NPPA
UniProt Synonym Gene Names
ANF; ANP
UniProt Entry Name
ANF_HORSE
NCBI Protein Information
natriuretic peptides A; ANF; ANP; prepronatriodilatin; atrial natriuretic factor; atrial natriuretic peptide; natriuretic peptide precursor A; prohormone for atrial natriuretic polypeptide (ANP)

UniProt Comments for NPPA

Function: Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3

By similarity.

Subcellular location: Secreted.

Post-translational modification: Cleaved by CORIN upon secretion to produce the functional hormone

By similarity.

Sequence similarities: Belongs to the natriuretic peptide family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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