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ETS Domain-Containing Protein Elk-1 (ELK1) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS966871

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter… More details

$1185 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ETS domain-containing protein Elk-1 (Elk1), Recombinant Protein
Full Product Name
Recombinant Mouse ETS domain-containing protein Elk-1 (Elk1)
Product Gene Name
Elk1 recombinant protein
Sequence
MDPSVTLWQF LLQLLREQGN GHIISWTSRD GGEFKLVDAE EVARLWGLRK NKTNMNYDKL SRALRYYYDK NIIRKVSGQK FVYKFVSYPE VAGCSTEDCP PQPEVSVTSA IAMAPATVHA GPGDTATGKP GTPKGAGMTG QGGLARSSRN EYMRSGLYST FTIQSLQPQP QPPIPPRPAS VLPNTTPAGV PAPASGSRST SPNPLEACLE AEEAGLPLQV ILTPPEAPNQ KSEELSLDPS FGHPQPPEVK VEGPKEELEA ARAGGFSSEA VKAEPEVSAS EGLLARLPAI LTENTAQVCG LSTSTTEITQ PQKGRKPRDL ELPLSPSLLG GQGPERTPGS GTSSGLQAPG PALTPSLLPT HTLTPVLLTP SSLPPSIHFW STLSPIAPRS PAKLSFQFPS SGSAQVHIPS ISVDGLSTPV VLSPGPQKP
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
45,271 Da
Sequence Positions
1-429, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P41969
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Elk1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Elk1 purchase

MBS966871 is a recombinant protein targeting Elk1. Also known as Recombinant Mouse ETS domain-containing protein Elk-1 (Elk1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Elk1. It may not necessarily be applicable to this product.

NCBI GI #
116292182
NCBI GeneID
13712
NCBI Accession #
NP_031948.4
UniProt Primary Accession #
P41969
UniProt Secondary Accession #
Q3V1M9
UniProt Related Accession #
P41969
GenBank Nucleotide #
NM_007922.5
NCBI Official Full Name
ETS domain-containing protein Elk-1
NCBI Official Synonym Full Names
ELK1, member of ETS oncogene family
NCBI Official Symbol
Elk1
NCBI Official Synonym Symbols
Elk-1
UniProt Protein Name
ETS domain-containing protein Elk-1
Protein Family
ETS domain-containing protein
UniProt Gene Name
Elk1
NCBI Protein Information
ETS domain-containing protein Elk-1

NCBI Summary for Elk1

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene may produce multiple isoforms by the use of alternative translational start codons. [provided by RefSeq, Mar 2012]
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UniProt Comments for Elk1

Transcription factor that binds to purine-rich DNA sequences. Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2 (). Induces target gene transcription upon JNK-signaling pathway stimulation ().
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Research Articles on Elk1

1. the effects of vitamin C inhibiting the apo(a) expression were attenuated by ELK1siRNA and Tet2siRNA. These results suggested vitamin C down-regulate apo(a) expression via Tet2-dependent DNA demethylation in HepG2 cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Elk1 recombinant protein

 Reference Product  PubMed Publications
 Mapk1 recombinant protein  >123 publications with Elk1 and Mapk1
 Mapk3 recombinant protein  >103 publications with Elk1 and Mapk3
 Srf recombinant protein  >69 publications with Elk1 and Srf
 Elk4 recombinant protein  >35 publications with Elk1 and Elk4
 Mapk14 recombinant protein  >2 publications with Elk1 and Mapk14

Pathways associated with Elk1 recombinant protein

 Products by Pathway  Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 ERK/MAPK Targets Pathway antibodies  ERK/MAPK Targets Pathway Diagram
 Endometrial Cancer Pathway antibodies  Endometrial Cancer Pathway Diagram
 Endometrial Cancer Pathway antibodies  Endometrial Cancer Pathway Diagram
 ErbB Signaling Pathway antibodies  ErbB Signaling Pathway Diagram
 ErbB Signaling Pathway antibodies  ErbB Signaling Pathway Diagram
 ErbB Signaling Pathway antibodies  ErbB Signaling Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram

Diseases associated with Elk1 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >114 publications with Elk1 and Neoplasms
 Nervous System Diseases Antibodies  >26 publications with Elk1 and Nervous System Diseases
 Adenocarcinoma Antibodies  >24 publications with Elk1 and Adenocarcinoma
 Necrosis Antibodies  >17 publications with Elk1 and Necrosis
 Inflammation Antibodies  >16 publications with Elk1 and Inflammation
 Breast Neoplasms Antibodies  >15 publications with Elk1 and Breast Neoplasms
 Drug Toxicity Antibodies  >13 publications with Elk1 and Drug Toxicity
 Atherosclerosis Antibodies  >11 publications with Elk1 and Atherosclerosis
 Lung Neoplasms Antibodies  >11 publications with Elk1 and Lung Neoplasms
 Prostatic Neoplasms Antibodies  >10 publications with Elk1 and Prostatic Neoplasms

Organs/Tissues associated with Elk1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Other Antibodies  >123 publications with Elk1 and Other
 Brain Antibodies  >96 publications with Elk1 and Brain
 Blood Antibodies  >60 publications with Elk1 and Blood
 Kidney Antibodies  >29 publications with Elk1 and Kidney
 Lung Antibodies  >29 publications with Elk1 and Lung
 Heart Antibodies  >24 publications with Elk1 and Heart
 Ovary Antibodies  >18 publications with Elk1 and Ovary
 Embryonic Tissue Antibodies  >18 publications with Elk1 and Embryonic Tissue
 Liver Antibodies  >13 publications with Elk1 and Liver
 Bone Antibodies  >13 publications with Elk1 and Bone
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