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Tyrosine-Protein Kinase Yes (YES1) Chicken Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS966936

This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a… More details

$2875 / 1 mg (E-Coli) +3 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tyrosine-protein kinase Yes (YES1), Recombinant Protein
Full Product Name
Recombinant Chicken Tyrosine-protein kinase Yes (YES1)
Product Gene Name
Product Synonym Gene Name
YES1; YES
Product Synonym Names
Recombinant Tyrosine-protein kinase Yes (YES1); Tyrosine-protein kinase Yes EC= 2.7.10.2; p61-Yes
Sequence
GCIKSKEDKG PAMKYRTDNT PEPISSHVSH YGSDSSQATQ SPAIKGSAVN FNSHSMTPFG GPSGMTPFGG ASSSFSAVPS PYPSTLTGGV TVFVALYDYE ARTTDDLSFK KGERFQIINN TEGDWWEARS IATGKTGYIP SNYVAPADSI QAEEWYFGKM GRKDAERLLL NPGNQRGIFL VRESETTKGA YSLSIRDWDE VRGDNVKHYK IRKLDNGGYY ITTRAQFESL QKLVKHYREH ADGLCHKLTT VCPTVKPQTQ GLAKDAWEIP RESLRLEVKL GQGCFGEVWM GTWNGTTKVA IKTLKPGTMM PEAFLQEAQI MKKLRHDKLV PLYAVVSEEP IYIVTEFMTK GSLLDFLKEG EGKFLKLPQL VDMAAQIADG MAYIERMNYI HRDLRAANIL VGDNLVCKIA DFGLARLIED NEYTARQGAK FPIKWTAPEA ALYGRFTIKS DVWSFGILLT ELVTKGRVPY PGMVNREVLE QVERGYRMPC PQGCPESLHE LMKLCWKKDP DERPTFEYIQ SFLEDYFTAT EPQYQPGDNL
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
60,792 Da
Sequence Positions
2-541
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 2; NC_006089.3 (101577601..101591372). Location: chromosome: 2
3D Structure
ModBase 3D Structure for P09324
Species
Gallus gallus (Chicken)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of YES1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for YES1 purchase

MBS966936 is a recombinant protein targeting YES1. Also known as Recombinant Chicken Tyrosine-protein kinase Yes (YES1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for YES1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tyrosine-protein kinase Yes
NCBI Official Synonym Full Names
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
NCBI Official Symbol
YES1
NCBI Official Synonym Symbols
YES
UniProt Protein Name
Tyrosine-protein kinase Yes
UniProt Synonym Protein Names
p61-Yes
UniProt Gene Name
YES1
UniProt Synonym Gene Names
YES
UniProt Entry Name
YES_CHICK
NCBI Protein Information
tyrosine-protein kinase Yes; p61-Yes; proto-oncogene tyrosine-protein kinase YES

UniProt Comments for YES1

Function: Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, differentiation, G2/M progression and cytokinesis

By similarity.

Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

Subcellular location: Cell membrane

By similarity. Cytoplasm › cytoskeleton › centrosome

By similarity. Cytoplasm › cytosol

By similarity.

Post-translational modification: Autophosphorylation at Tyr-424 maintains enzyme activity

By similarity.Palmitoylation at Cys-3 promotes membrane localization

By similarity.

Sequence similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.Contains 1 protein kinase domain.Contains 1 SH2 domain.Contains 1 SH3 domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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