Human POU2F1 Recombinant Protein – Cat# MBS967221

POU Domain, Class 2, Transcription Factor 1 (POU2F1) Human Recombinant Protein

Name: POU2F1 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS967221
Price: 1605 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS967221

MBS967221 is a recombinant protein targeting POU2F1. Also known as Recombinant Human POU domain, class 2, transcription factor 1 (POU2F1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1605 / 0.02 mg (E-Coli) +2 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

POU domain, class 2, transcription factor 1 (POU2F1), Recombinant Protein

Full Product Name

Recombinant Human POU domain, class 2, transcription factor 1 (POU2F1)

Product Gene Name

POU2F1 recombinant protein

Sequence

MNNPSETSKP SMESGDGNTG TQTNGLDFQK QPVPVGGAIS TAQAQAFLGH LHQVQLAGTS LQAAAQSLNV QSKSNEESGD SQQPSQPSQQ PSVQAAIPQT QLMLAGGQIT GLTLTPAQQQ LLLQQAQAQA QLLAAAVQQH SASQQHSAAG ATISASAATP MTQIPLSQPI QIAQDLQQLQ QLQQQNLNLQ QFVLVHPTTN LQPAQFIISQ TPQGQQGLLQ AQNLLTQLPQ QSQANLLQSQ PSITLTSQPA TPTRTIAATP IQTLPQSQST PKRIDTPSLE EPSDLEELEQ FAKTFKQRRI KLGFTQGDVG LAMGKLYGND FSQTTISRFE ALNLSFKNMC KLKPLLEKWL NDAENLSSDS SLSSPSALNS PGIEGLSRRR KKRTSIETNI RVALEKSFLE NQKPTSEEIT MIADQLNMEK EVIRVWFCNR RQKEKRINPP SSGGTSSSPI KAIFPSPTSL VATTPSLVTS SAATTLTVSP VLPLTSAAVT NLSVTGTSDT TSNNTATVIS TAPPASSAVT SPSLSPSPSA SASTSEASSA SETSTTQTTS TPLSSPLGTS QVMVTASGLQ TAAAAALQGA AQLPANASLA AMAAAAGLNP SLMAPSQFAA GGALLSLNPG TLSGALSPAL MSNSTLATIQ ALASGGSLPI TSLDATGNLV FANAGGAPNI VTAPLFLNPQ NLSLLTSNPV SLVSAAAASA GNSAPVASLH ATSTSAESIQ NSLFTVASAS GAASTTTTAS KAQ

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

72,082 Da

Sequence Positions

1-743, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

164175

3D Structure

ModBase 3D Structure for P14859

Species

Human

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of POU2F1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for POU2F1. It may not necessarily be applicable to this product.

NCBI GI #

311771667

NCBI GeneID

5451

NCBI Accession #

NP_001185712.1

UniProt Primary Accession #

P14859

UniProt Secondary Accession #

Q5TBT7; Q6PK46; Q8NEU9; Q9BPV1; B1AL91; B1AL93; B4E029; J3KP77

UniProt Related Accession #

P14859

GenBank Nucleotide #

NM_001198783.1

NCBI Official Full Name

POU domain, class 2, transcription factor 1 isoform 2

NCBI Official Synonym Full Names

POU class 2 homeobox 1

NCBI Official Symbol

POU2F1

NCBI Official Synonym Symbols

OCT1; OTF1; oct-1B

UniProt Protein Name

POU domain, class 2, transcription factor 1

UniProt Synonym Protein Names

NF-A1; Octamer-binding protein 1; Oct-1; Octamer-binding transcription factor 1; OTF-1

Protein Family

POU domain, class 2, transcription factor

UniProt Gene Name

POU2F1

UniProt Synonym Gene Names

OCT1; OTF1; Oct-1; OTF-1

NCBI Protein Information

POU domain, class 2, transcription factor 1

NCBI Summary for POU2F1

The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010]

UniProt Comments for POU2F1

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (). In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.

Research Articles on POU2F1

1. Children with certain OCT1 genotypes have higher risk for respiratory depression and nausea and vomiting, postoperatively, following morphine administration.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with POU2F1 recombinant protein

Reference Product	PubMed Publications
SP1 recombinant protein	>39 publications with POU2F1 and SP1
POU2AF1 recombinant protein	>25 publications with POU2F1 and POU2AF1
HNF1A recombinant protein	>5 publications with POU2F1 and HNF1A
SOX2 recombinant protein	>5 publications with POU2F1 and SOX2
TBP recombinant protein	>4 publications with POU2F1 and TBP
RELA recombinant protein	>3 publications with POU2F1 and RELA
NFYA recombinant protein	>3 publications with POU2F1 and NFYA
BRCA1 recombinant protein	>3 publications with POU2F1 and BRCA1
ESR1 recombinant protein	>2 publications with POU2F1 and ESR1
STAT5A recombinant protein	>2 publications with POU2F1 and STAT5A

Pathways associated with POU2F1 recombinant protein

Products by Pathway	Pathway Diagram
ATF-2 Transcription Factor Network Pathway antibodies	ATF-2 Transcription Factor Network Pathway Diagram
Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies	Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
Calcium Signaling In The CD4+ TCR Pathway antibodies	Calcium Signaling In The CD4+ TCR Pathway Diagram
FOXA1 Transcription Factor Network Pathway antibodies	FOXA1 Transcription Factor Network Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Glucocorticoid Receptor Regulatory Network Pathway antibodies	Glucocorticoid Receptor Regulatory Network Pathway Diagram
RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway antibodies	RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway Diagram
RNA Polymerase III Abortive And Retractive Initiation Pathway antibodies	RNA Polymerase III Abortive And Retractive Initiation Pathway Diagram
RNA Polymerase III Transcription Pathway antibodies	RNA Polymerase III Transcription Pathway Diagram
RNA Polymerase III Transcription Initiation Pathway antibodies	RNA Polymerase III Transcription Initiation Pathway Diagram

Diseases associated with POU2F1 recombinant protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>68 publications with POU2F1 and Neoplasms
Necrosis Antibodies	>13 publications with POU2F1 and Necrosis
Inflammation Antibodies	>12 publications with POU2F1 and Inflammation
Hepatitis Antibodies	>6 publications with POU2F1 and Hepatitis
Lung Diseases Antibodies	>6 publications with POU2F1 and Lung Diseases
Drug Toxicity Antibodies	>6 publications with POU2F1 and Drug Toxicity
Kidney Diseases Antibodies	>4 publications with POU2F1 and Kidney Diseases
Carcinoma, Hepatocellular Antibodies	>4 publications with POU2F1 and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>3 publications with POU2F1 and Liver Neoplasms
Brain Diseases Antibodies	>3 publications with POU2F1 and Brain Diseases

Organs/Tissues associated with POU2F1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>126 publications with POU2F1 and Blood
Liver Antibodies	>38 publications with POU2F1 and Liver
Kidney Antibodies	>30 publications with POU2F1 and Kidney
Brain Antibodies	>30 publications with POU2F1 and Brain
Embryonic Tissue Antibodies	>17 publications with POU2F1 and Embryonic Tissue
Vascular Antibodies	>13 publications with POU2F1 and Vascular
Lung Antibodies	>13 publications with POU2F1 and Lung
Spleen Antibodies	>12 publications with POU2F1 and Spleen
Muscle Antibodies	>11 publications with POU2F1 and Muscle
Thymus Antibodies	>8 publications with POU2F1 and Thymus