Human ODC1 Recombinant Protein – Cat# MBS967514

Ornithine Decarboxylase (ODC1) Human Recombinant Protein

Name: ODC1 Recombinant Protein; Ornithine Decarboxylase; Human; MyBioSource
Brand: MyBioSource
SKU: MBS967514
Price: 315 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS967514

Key enzyme of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. More details

$315 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ornithine decarboxylase (ODC1), Recombinant Protein

Full Product Name

Recombinant Human Ornithine decarboxylase (ODC1)

Product Gene Name

ODC1 recombinant protein

Product Synonym Names

Ornithine decarboxylase; ODC; EC=4.1.1.17

Sequence

MNNFGNEEFD CHFLDEGFTA KDILDQKINE VSSSDDKDAF YVADLGDILK KHLRWLKALP RVTPFYAVKC NDSKAIVKTL AATGTGFDCA SKTEIQLVQS LGVPPERIIY ANPCKQVSQI KYAANNGVQM MTFDSEVELM KVARAHPKAK LVLRIATDDS KAVCRLSVKF GATLRTSRLL LERAKELNID VVGVSFHVGS GCTDPETFVQ AISDARCVFD MGAEVGFSMY LLDIGGGFPG SEDVKLKFEE ITGVINPALD KYFPSDSGVR IIAEPGRYYV ASAFTLAVNI IAKKIVLKEQ TGSDDEDESS EQTFMYYVND GVYGSFNCIL YDHAHVKPLL QKRPKPDEKY YSSSIWGPTC DGLDRIVERC DLPEMHVGDW MLFENMGAYT VAAASTFNGF QRPTIYYVMS GPAWQLMQQF QNPDFPPEVE EQDASTLPVS CAWESGMKRH RAACASASIN V

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

71.1 kDa

Sequence Positions

1-461aa; Full Length

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

165640

3D Structure

ModBase 3D Structure for P11926

Species

Homo sapiens (Human)

Production Note

Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.

Product Categories/Family for ODC1 recombinant protein

Signal Transduction

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ODC1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ODC1 purchase

MBS967514 is a recombinant protein targeting ODC1. Also known as Recombinant Human Ornithine decarboxylase (ODC1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for ODC1. It may not necessarily be applicable to this product.

NCBI GI #

563580287

NCBI GeneID

4953

NCBI Accession #

NP_001274118.1

UniProt Primary Accession #

P11926

UniProt Secondary Accession #

Q53TU3; Q6LDS9

UniProt Related Accession #

P11926

GenBank Nucleotide #

NM_001287189.1

NCBI Official Full Name

ornithine decarboxylase isoform 1

NCBI Official Synonym Full Names

ornithine decarboxylase 1

NCBI Official Symbol

ODC1

NCBI Official Synonym Symbols

ODC

UniProt Protein Name

Ornithine decarboxylase

Protein Family

Mitochondrial 2-oxodicarboxylate carrier

UniProt Gene Name

ODC1

UniProt Synonym Gene Names

ODC

UniProt Entry Name

DCOR_HUMAN

NCBI Protein Information

ornithine decarboxylase

NCBI Summary for ODC1

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013]

UniProt Comments for ODC1

ODC: the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008]

Protein type: Amino Acid Metabolism - arginine and proline; Lyase; Other Amino Acids Metabolism - glutathione; Cell cycle regulation; EC 4.1.1.17

Chromosomal Location of Human Ortholog: 2p25

Cellular Component: cytoplasm; cytosol

Molecular Function: protein homodimerization activity; ornithine decarboxylase activity

Biological Process: response to virus; positive regulation of cell proliferation; regulation of protein catabolic process; kidney development; regulation of amino acid metabolic process; putrescine biosynthetic process from ornithine; polyamine metabolic process

Disease: Colorectal Cancer

Research Articles on ODC1

1. BTF3, HINT1, NDRG1 and ODC1 protein over-expression in human prostate cancer tissue

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ODC1 recombinant protein

Reference Product	PubMed Publications
AGMAT recombinant protein	>2 publications with ODC1 and AGMAT
OAZ2 recombinant protein	>2 publications with ODC1 and OAZ2
SAT1 recombinant protein	>2 publications with ODC1 and SAT1
SRM recombinant protein	>2 publications with ODC1 and SRM
OAZ1 recombinant protein	>1 publications with ODC1 and OAZ1

Pathways associated with ODC1 recombinant protein

Products by Pathway	Pathway Diagram
Arginine And Proline Metabolism Pathway antibodies	Arginine And Proline Metabolism Pathway Diagram
Arginine And Proline Metabolism Pathway antibodies	Arginine And Proline Metabolism Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Amino Acids And Derivatives Pathway antibodies	Metabolism Of Amino Acids And Derivatives Pathway Diagram
Metabolism Of Polyamines Pathway antibodies	Metabolism Of Polyamines Pathway Diagram
Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway antibodies	Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway Diagram
Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway antibodies	Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway Diagram

Diseases associated with ODC1 recombinant protein

Disease Name	Pubmed Publications
Colorectal Neoplasms Antibodies	>5 publications with ODC1 and Colorectal Neoplasms
Carcinoma Antibodies	>3 publications with ODC1 and Carcinoma
Neoplasms, Experimental Antibodies	>2 publications with ODC1 and Neoplasms, Experimental
Colonic Neoplasms Antibodies	>2 publications with ODC1 and Colonic Neoplasms
Hypertrophy Antibodies	>1 publications with ODC1 and Hypertrophy
Lung Neoplasms Antibodies	>1 publications with ODC1 and Lung Neoplasms
Breast Neoplasms Antibodies	>1 publications with ODC1 and Breast Neoplasms
Hypertension Antibodies	>1 publications with ODC1 and Hypertension
Heart Diseases Antibodies	>1 publications with ODC1 and Heart Diseases
Necrosis Antibodies	>1 publications with ODC1 and Necrosis

Organs/Tissues associated with ODC1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>13 publications with ODC1 and Bone
Connective Tissue Antibodies	>4 publications with ODC1 and Connective Tissue
Heart Antibodies	>3 publications with ODC1 and Heart
Muscle Antibodies	>3 publications with ODC1 and Muscle
Brain Antibodies	>3 publications with ODC1 and Brain
Vascular Antibodies	>2 publications with ODC1 and Vascular
Embryonic Tissue Antibodies	>2 publications with ODC1 and Embryonic Tissue
Ear Antibodies	>1 publications with ODC1 and Ear
Kidney Antibodies	>1 publications with ODC1 and Kidney
Umbilical Cord Antibodies	>1 publications with ODC1 and Umbilical Cord