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Neuronal Acetylcholine Receptor Subunit Beta-4 (CHRNB4) Chicken Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS967524

MBS967524 is a recombinant protein targeting CHRNB4. Also known as Recombinant Chicken Neuronal acetylcholine receptor subunit beta-4 (CHRNB4). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Neuronal acetylcholine receptor subunit beta-4 (CHRNB4), Recombinant Protein
Full Product Name
Recombinant Chicken Neuronal acetylcholine receptor subunit beta-4 (CHRNB4)
Product Gene Name
CHRNB4 recombinant protein
Product Synonym Gene Name
CHRNB4
Product Synonym Names
Recombinant Neuronal acetylcholine receptor subunit beta-4 (CHRNB4); Neuronal acetylcholine receptor subunit beta-4; Neuronal acetylcholine receptor non-alpha-3 chain; N-alpha 3
Sequence
ADAEEKLMNH LLSPDRYNKL IRPAVNSSQL VSIELQVSLA QLISVNEREQ IMTTNVWLNQ EWIDYRLAWK PSDYEGINML RIPAKHIWLP DIVLYNNADG TYEVSLYTNA IVQNNGSIRW LPPAIYKSAC KIEVKHFPFD QQNCTLKFRS WTYDHTEIDM VLKTSMASMD DFTPSGEWDI VALPGRRTEN PLDPNYVDVT YDFIIKRKPL FYTINLIIPC VLITSLAILV FYLPSDCGEK MTLCISVLLA LTVFLLLISK IVPPTSLDVP LIGKYLMFTM VLVTFSIVTS VCVLNVHHRS PSTHTMPPWV KLVFLERLPA YLFMKRPENN SPRQKPANCK KTRAENLCMD PADFYKNSTY FVNTASAKKY DMKITDTLDN VSSHQDFRLR TGTKFSPEVQ EAIDGVSFIA EHMKSDDNDQ SVIEDWKYVA MVVDRLFLWI FVLVCVLGTV GLFLQPLFQN HIAATNP
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
53,785 Da
Sequence Positions
4-470
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 10; NC_006097.3 (3104237..3115886). Location: chromosome: 10
3D Structure
ModBase 3D Structure for P26153
Species
Gallus gallus (Chicken)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CHRNB4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CHRNB4. It may not necessarily be applicable to this product.

NCBI GI #
113110
NCBI GeneID
395613
NCBI Accession #
P26153.1
UniProt Primary Accession #
P26153
UniProt Related Accession #
P26153
NCBI Official Full Name
Neuronal acetylcholine receptor subunit beta-4
NCBI Official Symbol
CHRNB4
UniProt Protein Name
Neuronal acetylcholine receptor subunit beta-4
UniProt Synonym Protein Names
Neuronal acetylcholine receptor non-alpha-3 chain
Protein Family
Neuronal acetylcholine receptor
UniProt Gene Name
CHRNB4
UniProt Synonym Gene Names
N-alpha 3
UniProt Entry Name
ACHB4_CHICK
NCBI Protein Information
neuronal acetylcholine receptor subunit beta-4; N-alpha 3; neuronal acetylcholine receptor non-alpha-3 chain; cholinergic receptor, nicotinic, beta polypeptide 4; nicotinic acetylcholine receptor beta-4 (non-alpha-3) subunit

UniProt Comments for CHRNB4

Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Subunit structure: Neuronal AChR seems to be composed of two different type of subunits: alpha and non-alpha (also called beta). A functional receptor seems to consist of two alpha-chains and three non-alpha chains.

Subcellular location: Cell junction › synapse › postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Developmental stage: High levels in the developing ciliary and superior cervical ganglia.

Sequence similarities: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta-4/CHRNB4 sub-subfamily. [View classification]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CHRNB4 recombinant protein

 Products by Pathway  Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Organs/Tissues associated with CHRNB4 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with CHRNB4 and Blood
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