Human CD24 Active Protein – Cat# MBS967923

Signal Transducer CD24 (CD24) Human Active Protein

Name: CD24 Active Protein; Signal Transducer CD24; Human; MyBioSource
Brand: MyBioSource
SKU: MBS967923
Price: 470 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS967923

MBS967923 is an active protein targeting CD24. Also known as Recombinant Human Signal transducer CD24 (CD24)-Nanoparticle (Active). Host: Mammalian Cell. More details

$470 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Signal transducer CD24 (CD24), Active Protein

Full Product Name

Recombinant Human Signal transducer CD24 (CD24)-Nanoparticle (Active)

Product Gene Name

CD24 active protein

Sequence

SETTTGTSSN SSQSTSNSGL APNPTNATTK AAG

Host

Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

8,097 Da

Sequence Positions

27-59aa, Cytoplasmic domain

OMIM

126200

3D Structure

ModBase 3D Structure for P25063

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Species

Human

Biological Activity

Activity: Measured by its binding ability in a functional ELISA. Immobilized human CD24 at 2 ?g/ml can bind anti-CD24 recombinant Monoclonal Antibody, the the EC50 is 5.409-8.219 ng/ml.

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CD24 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD24. It may not necessarily be applicable to this product.

NCBI GI #

619329006

NCBI GeneID

100133941

NCBI Accession #

NP_001278666.1

UniProt Primary Accession #

P25063

UniProt Secondary Accession #

Q16257; Q53XS0

UniProt Related Accession #

P25063

GenBank Nucleotide #

NM_001291737.1

NCBI Official Full Name

signal transducer CD24 isoform a preproprotein

NCBI Official Synonym Full Names

CD24 molecule

NCBI Official Symbol

CD24

NCBI Official Synonym Symbols

CD24A

UniProt Protein Name

Signal transducer CD24

UniProt Synonym Protein Names

Small cell lung carcinoma cluster 4 antigen; CD_antigen: CD24

Protein Family

Signal transducer

UniProt Gene Name

CD24

UniProt Synonym Gene Names

CD24A

NCBI Protein Information

signal transducer CD24

NCBI Summary for CD24

This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

UniProt Comments for CD24

May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells (PubMed:11313396). In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity ().

Research Articles on CD24

1. CD133+CD24lo phenotype defines 5-FU-resistant human colon cancer stem cell-like cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CD24 active protein

Reference Product	PubMed Publications
CD44 active protein	>749 publications with CD24 and CD44
CD19 active protein	>163 publications with CD24 and CD19
CD22 active protein	>67 publications with CD24 and CD22
GLI1 active protein	>15 publications with CD24 and GLI1
L1CAM active protein	>15 publications with CD24 and L1CAM
LYN active protein	>3 publications with CD24 and LYN
SIGLEC10 active protein	>3 publications with CD24 and SIGLEC10
FGR active protein	>1 publications with CD24 and FGR
SELP active protein	>1 publications with CD24 and SELP

Pathways associated with CD24 active protein

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
L1CAM Interactions Pathway antibodies	L1CAM Interactions Pathway Diagram

Diseases associated with CD24 active protein

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>454 publications with CD24 and Breast Neoplasms
Carcinoma Antibodies	>344 publications with CD24 and Carcinoma
Neoplasm Metastasis Antibodies	>173 publications with CD24 and Neoplasm Metastasis
Adenocarcinoma Antibodies	>173 publications with CD24 and Adenocarcinoma
Neoplasms, Experimental Antibodies	>135 publications with CD24 and Neoplasms, Experimental
Cell Transformation, Neoplastic Antibodies	>77 publications with CD24 and Cell Transformation, Neoplastic
Pancreatic Neoplasms Antibodies	>74 publications with CD24 and Pancreatic Neoplasms
Lung Neoplasms Antibodies	>71 publications with CD24 and Lung Neoplasms
Inflammation Antibodies	>70 publications with CD24 and Inflammation
Nervous System Diseases Antibodies	>60 publications with CD24 and Nervous System Diseases

Organs/Tissues associated with CD24 active protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>570 publications with CD24 and Blood
Bone Antibodies	>236 publications with CD24 and Bone
Bone Marrow Antibodies	>208 publications with CD24 and Bone Marrow
Lymph Node Antibodies	>127 publications with CD24 and Lymph Node
Lymph Antibodies	>123 publications with CD24 and Lymph
Lung Antibodies	>103 publications with CD24 and Lung
Kidney Antibodies	>94 publications with CD24 and Kidney
Liver Antibodies	>92 publications with CD24 and Liver
Mammary Gland Antibodies	>86 publications with CD24 and Mammary Gland
Brain Antibodies	>84 publications with CD24 and Brain