Rat MCHR1 Recombinant Protein – Cat# MBS968069

Melanin-Concentrating Hormone Receptor 1 (MCHR1) Rat Recombinant Protein

Name: MCHR1 Recombinant Protein; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS968069
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS968069

MBS968069 is a recombinant protein targeting Mchr1. Also known as Recombinant Rat Melanin-concentrating hormone receptor 1 (Mchr1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Melanin-concentrating hormone receptor 1 (Mchr1), Recombinant Protein

Full Product Name

Recombinant Rat Melanin-concentrating hormone receptor 1 (Mchr1)

Product Gene Name

Mchr1 recombinant protein

Product Synonym Gene Name

Mchr1; Gpr24, Slc1

Product Synonym Names

Recombinant Melanin-concentrating hormone receptor 1 (Mchr1); Melanin-concentrating hormone receptor 1; MCH receptor 1; MCH-R1; MCHR-1; G-protein coupled receptor 24 MCH-1R; MCH1R; MCHR SLC-1 Somatostatin receptor-like protein

Sequence

QATCTGCMDL QTSLLSTGPN ASNISDGQDN LTLPGSPPRT GSVSYINIIM PSVFGTICLL GIVGNSTVIF AVVKKSKLHW CSNVPDIFII NLSVVDLLFL LGMPFMIHQL MGNGVWHFGE TMCTLITAMD ANSQFTSTYI LTAMTIDRYL ATVHPISSTK FRKPSMATLV ICLLWALSFI SITPVWLYAR LIPFPGGAVG CGIRLPNPDT DLYWFTLYQF FLAFALPFVV ITAAYVKILQ RMTSSVAPAS QRSIRLRTKR VTRTAIAICL VFFVCWAPYY VLQLTQLSIS RPTLTFVYLY NAAISLGYAN SCLNPFVYIV LCETFRKRLV LSVKPAAQGQ LRTVSNAQTA DEERTESKGT

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

39,728 Da

Sequence Positions

1-360

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 7; NC_005106.3 (122432538..122435016). Location: 7q34

3D Structure

ModBase 3D Structure for P97639

Species

Rattus norvegicus (Rat)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Mchr1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Mchr1. It may not necessarily be applicable to this product.

NCBI GI #

13929068

NCBI GeneID

83567

NCBI Accession #

NP_113946.1

UniProt Primary Accession #

P97639

UniProt Related Accession #

P97639

GenBank Nucleotide #

NM_031758.1

NCBI Official Full Name

melanin-concentrating hormone receptor 1

NCBI Official Synonym Full Names

melanin-concentrating hormone receptor 1

NCBI Official Symbol

Mchr1

NCBI Official Synonym Symbols

Slc1; Gpr24; Mch-1r

UniProt Protein Name

Melanin-concentrating hormone receptor 1

UniProt Synonym Protein Names

G-protein coupled receptor 24; MCH-1R; MCH1R; MCHR; SLC-1; Somatostatin receptor-like protein

Protein Family

Melanin-concentrating hormone receptor

UniProt Gene Name

Mchr1

UniProt Synonym Gene Names

Gpr24; Slc1; MCH receptor 1; MCH-R1; MCHR-1; MCH1R; MCHR

UniProt Entry Name

MCHR1_RAT

NCBI Protein Information

melanin-concentrating hormone receptor 1; MCHR; MCH1R; SLC-1; MCH-R1; MCHR-1; MCH receptor 1; G protein-coupled receptor 24; G-protein coupled receptor 24; somatostatin receptor-like protein

NCBI Summary for Mchr1

receptor for melanin-concentrating hormone (MCH); may mediate intracellular Ca2+ levels, forskolin-stimulated cyclic AMP production, and activation of mitogen-activated protein kinase; may play role in energy homeostasis [RGD, Feb 2006]

UniProt Comments for Mchr1

MCHR1: Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass

Cellular Component: nonmotile primary cilium; integral to membrane; plasma membrane

Molecular Function: protein C-terminus binding; hormone binding; melanin-concentrating hormone receptor activity

Biological Process: elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; neuropeptide signaling pathway; positive regulation of calcium ion transport

Research Articles on Mchr1

1. Data suggest that MCH and its receptor (MCHR1) form an orexigenic system whose expression is affected in conditioned taste aversion. MCHR1 expression is up-regulated in hypothalamus and brain stem (and possibly amygdala) of aversive animals.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Mchr1 recombinant protein

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram

Diseases associated with Mchr1 recombinant protein

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>8 publications with Mchr1 and Disease Models, Animal
Mental Disorders Antibodies	>8 publications with Mchr1 and Mental Disorders
Mood Disorders Antibodies	>7 publications with Mchr1 and Mood Disorders
Brain Diseases Antibodies	>6 publications with Mchr1 and Brain Diseases
Insulin Resistance Antibodies	>5 publications with Mchr1 and Insulin Resistance
Neoplasms Antibodies	>2 publications with Mchr1 and Neoplasms
Learning Disorders Antibodies	>2 publications with Mchr1 and Learning Disorders
Drug Toxicity Antibodies	>2 publications with Mchr1 and Drug Toxicity
Catalepsy Antibodies	>1 publications with Mchr1 and Catalepsy
Fever Antibodies	>1 publications with Mchr1 and Fever

Organs/Tissues associated with Mchr1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>65 publications with Mchr1 and Brain