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Nadph:adrenodoxin Oxidoreductase, Mitochondrial (FDXR) Bovine Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS968070

This gene encodes a mitochondrial flavoprotein that initiates electron transport for cytochromes P450 receiving electrons from NADPH. Multiple alternatively spliced transcript variants of this gene have been described although the full-length nature of only… More details

$385 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NADPH:adrenodoxin oxidoreductase, mitochondrial (FDXR), Recombinant Protein
Full Product Name
Recombinant Bovine NADPH:adrenodoxin oxidoreductase, mitochondrial (FDXR)
Product Gene Name
FDXR recombinant protein
Sequence
STQEQTPQIC VVGSGPAGFY TAQHLLKHHS RAHVDIYEKQ LVPFGLVRFG VAPDHPEVKN VINTFTQTAR SDRCAFYGNV EVGRDVTVQE LQDAYHAVVL SYGAEDHQAL DIPGEELPGV FSARAFVGWY NGLPENRELA PDLSCDTAVI LGQGNVALDV ARILLTPPDH LEKTDITEAA LGALRQSRVK TVWIVGRRGP LQVAFTIKEL REMIQLPGTR PMLDPADFLG LQDRIKEAAR PRKRLMELLL RTATEKPGVE EAARRASASR AWGLRFFRSP QQVLPSPDGR RAAGIRLAVT RLEGIGEATR AVPTGDVEDL PCGLVLSSIG YKSRPIDPSV PFDPKLGVVP NMEGRVVDVP GLYCSGWVKR GPTGVITTTM TDSFLTGQIL LQDLKAGHLP SGPRPGSAFI KALLDSRGVW PVSFSDWEKL DAEEVSRGQA SGKPREKLLD PQEMLRLLGH
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
52.8 kDa
Sequence Positions
33-492aa; Full Length of Mature Protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P08165
Species
Bovine
Production Note
Special Offer: The E Coli, Yeast host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Coli, Yeasthost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli, Yeast host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli, Yeast host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FDXR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FDXR purchase

MBS968070 is a recombinant protein targeting FDXR. Also known as Recombinant Bovine NADPH:adrenodoxin oxidoreductase, mitochondrial (FDXR). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for FDXR. It may not necessarily be applicable to this product.

NCBI GI #
27807249
NCBI GeneID
282604
NCBI Accession #
NP_777116.1
UniProt Primary Accession #
P08165
UniProt Secondary Accession #
Q58CY0; Q95KN8
UniProt Related Accession #
P08165
GenBank Nucleotide #
NM_174691.1
NCBI Official Full Name
NADPH:adrenodoxin oxidoreductase, mitochondrial
NCBI Official Synonym Full Names
ferredoxin reductase
NCBI Official Symbol
FDXR
NCBI Official Synonym Symbols
AR; AdR
UniProt Protein Name
NADPH:adrenodoxin oxidoreductase, mitochondrial
UniProt Synonym Protein Names
Ferredoxin--NADP(+) reductase; Ferredoxin reductase
UniProt Gene Name
FDXR
UniProt Synonym Gene Names
ADXR; AR; Adrenodoxin reductase; Ferredoxin reductase
NCBI Protein Information
NADPH:adrenodoxin oxidoreductase, mitochondrial

UniProt Comments for FDXR

Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
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Research Articles on FDXR

1. S. pombe is either very robust to mitochondrial reactive oxygen species (ROS) production or does not undergo apoptotic cell death in response to mitochondrial ROS at all.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with FDXR recombinant protein

 Products by Pathway  Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Pathway antibodies  Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Pathway Diagram
 Transmission Across Chemical Synapses Pathway antibodies  Transmission Across Chemical Synapses Pathway Diagram
 Unblocking Of NMDA Receptor, Glutamate Binding And Activation Pathway antibodies  Unblocking Of NMDA Receptor, Glutamate Binding And Activation Pathway Diagram

Diseases associated with FDXR recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >11 publications with FDXR and Neoplasms
 Gastrointestinal Diseases Antibodies  >4 publications with FDXR and Gastrointestinal Diseases
 Carcinoma Antibodies  >3 publications with FDXR and Carcinoma
 Neoplasms, Experimental Antibodies  >2 publications with FDXR and Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >2 publications with FDXR and Cardiovascular Diseases
 Cell Transformation, Neoplastic Antibodies  >2 publications with FDXR and Cell Transformation, Neoplastic
 Kidney Failure, Chronic Antibodies  >1 publications with FDXR and Kidney Failure, Chronic
 Adenocarcinoma Antibodies  >1 publications with FDXR and Adenocarcinoma
 Nervous System Diseases Antibodies  >1 publications with FDXR and Nervous System Diseases
 Vascular Diseases Antibodies  >1 publications with FDXR and Vascular Diseases

Organs/Tissues associated with FDXR recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >1 publications with FDXR and Pancreas
 Skin Antibodies  >1 publications with FDXR and Skin
 Intestine Antibodies  >1 publications with FDXR and Intestine
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