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Serine/Threonine-Protein Phosphatase 2a 65 Kda Regulatory Subunit A Beta Isoform (PPP2R1B) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS968359

This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major SerThr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core… More details

$1395 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PPP2R1B), Recombinant Protein
Full Product Name
Recombinant Human Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PPP2R1B)
Sequence
AGASELGTGP GAAGGDGDDS LYPIAVLIDE LRNEDVQLRL NSIKKLSTIA LALGVERTRS ELLPFLTDTI YDEDEVLLAL AEQLGNFTGL VGGPDFAHCL LPPLENLATV EETVVRDKAV ESLRQISQEH TPVALEAYFV PLVKRLASGD WFTSRTSACG LFSVCYPRAS NAVKAEIRQQ FRSLCSDDTP MVRRAAASKL GEFAKVLELD SVKSEIVPLF TSLASDEQDS VRLLAVEACV SIAQLLSQDD LETLVMPTLR QAAEDKSWRV RYMVADRFSE LQKAMGPKIT LNDLIPAFQN LLKDCEAEVR AAAAHKVKEL GENLPIEDRE TIIMNQILPY IKELVSDTNQ HVKSALASVI MGLSTILGKE NTIEHLLPLF LAQLKDECPD VRLNIISNLD CVNEVIGIRQ LSQSLLPAIV ELAEDAKWRV RLAIIEYMPL LAGQLGVEFF DEKLNSLCMA WLVDHVYAIR EAATNNLMKL VQKFGTEWAQ NTIVPKVLVM ANDPNYLHRM TTLFCINALS EACGQEITTK QMLPIVLKMA GDQVANVRFN VAKSLQKIGP ILDTNALQGE VKPVLQKLGQ DEDMDVKYFA QEAISVLALA
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
52,214 Da
Sequence Positions
2-601, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
603113
3D Structure
ModBase 3D Structure for P30154
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PPP2R1B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPP2R1B purchase

MBS968359 is a recombinant protein targeting PPP2R1B. Also known as Recombinant Human Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PPP2R1B). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for PPP2R1B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform d
NCBI Official Synonym Full Names
protein phosphatase 2 scaffold subunit Abeta
NCBI Official Symbol
PPP2R1B
NCBI Official Synonym Symbols
PR65B; PP2A-Abeta
UniProt Protein Name
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
UniProt Synonym Protein Names
PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta
UniProt Gene Name
PPP2R1B
NCBI Protein Information
serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

NCBI Summary for PPP2R1B

This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
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UniProt Comments for PPP2R1B

The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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