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Muellerian-Inhibiting Factor (AMH) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Popular Catalog #: MBS968365

This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. More details

$315 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Muellerian-inhibiting factor (Amh), Recombinant Protein
Full Product Name
Recombinant Mouse Muellerian-inhibiting factor (Amh), partial
Product Gene Name
Amh recombinant protein
Product Synonym Names
Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance; MIS
Sequence
DKGQDGPCAL RELSVDLRAE RSVLIPETYQ ANNCQGACRW PQSDRNPRYG NHVVLLLKMQ ARGAALGRLP CCVPTAYAGK LLISLSEERI SADHVPNMVA TEC
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Molecular Weight
11.3 kDa
Sequence Positions
450-552aa; Partial
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P27106
Production Note
Special Offer: The E Coli, Yeast host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Coli, Yeasthost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli, Yeast host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli, Yeast host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

SDS-Page of Amh recombinant protein

Mouse AMH Recombinant Protein – Cat# MBS968365

Product References and Citations for Amh recombinant protein

Expression of the mouse anti-Mullerian hormone gene suggests a role in both male and female sexual differentiation.Muensterberg A., Lovell-Badge R.Development 113:613-624(1991) A GNRP-like gene shares a bidirectional promoter with SAP62 immediately upstream of AMH.Dresser D.W., Jamin S., Atkins C.J., Guerrier D. The genes for a spliceosome protein (SAP62) and the anti-Mullerian hormone (AMH) are contiguous.Dresser D.W., Hacker A., Lovell-Badge R., Guerrier D.Hum. Mol. Genet. 4:1613-1618(1995)

Other Notes

Small volumes of Amh recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Amh purchase

MBS968365 is a recombinant protein targeting Amh. Also known as Recombinant Mouse Muellerian-inhibiting factor (Amh), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Amh. It may not necessarily be applicable to this product.

NCBI GI #
127110
NCBI GeneID
11705
NCBI Accession #
P27106.1
UniProt Primary Accession #
P27106
UniProt Related Accession #
P27106
NCBI Official Full Name
Muellerian-inhibiting factor
NCBI Official Synonym Full Names
anti-Mullerian hormone
NCBI Official Symbol
Amh
NCBI Official Synonym Symbols
MIS
UniProt Protein Name
Muellerian-inhibiting factor
UniProt Synonym Protein Names
Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance; MIS
Protein Family
Muellerian-inhibiting factor
UniProt Gene Name
Amh
UniProt Synonym Gene Names
AMH; MIS
UniProt Entry Name
MIS_MOUSE
NCBI Protein Information
muellerian-inhibiting factor

NCBI Summary for Amh

This gene is a member of the transforming growth factor-beta superfamily of growth and differentiation factors. The encoded protein is produced in fetal Sertoli cells during male gonadal differentiation. The protein binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in developing male embryos. In humans, some mutations in this gene are associated with persistent Mullerian duct syndrome (PMDS). [provided by RefSeq, Apr 2013]
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UniProt Comments for Amh

AMH: This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. Defects in AMH are the cause of persistent Muellerian duct syndrome type 1 (PMDS1). PMDS1 is a form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: cytoplasm; extracellular space

Molecular Function: hormone activity; receptor binding; transforming growth factor beta receptor binding

Biological Process: activation of NF-kappaB transcription factor; cell-cell signaling; Mullerian duct regression; preantral ovarian follicle growth; urogenital system development
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Research Articles on Amh

1. AMH and FOXL2 collaboratively work to reserve ovarian follicles. AMH is an endogenous target gene of FOXL2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Amh recombinant protein

 Reference Product  PubMed Publications
 Sox9 recombinant protein  >84 publications with Amh and Sox9
 Amhr2 recombinant protein  >47 publications with Amh and Amhr2
 Nr5a1 recombinant protein  >29 publications with Amh and Nr5a1
 Gata4 recombinant protein  >25 publications with Amh and Gata4
 Bmpr2 recombinant protein  >14 publications with Amh and Bmpr2
 Bmpr1b recombinant protein  >6 publications with Amh and Bmpr1b
 Fgf2 recombinant protein  >5 publications with Amh and Fgf2
 Bmpr1a recombinant protein  >4 publications with Amh and Bmpr1a
 Zfpm2 recombinant protein  >3 publications with Amh and Zfpm2
 Acvr1 recombinant protein  >2 publications with Amh and Acvr1

Pathways associated with Amh recombinant protein

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 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
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 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 CAMP Signaling Pathway antibodies  CAMP Signaling Pathway Diagram
 CAMP Signaling Pathway antibodies  CAMP Signaling Pathway Diagram
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