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Thromboxane-A Synthase (TBXAS1) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS968428

MBS968428 is a recombinant protein targeting Tbxas1. Also known as Recombinant Rat Thromboxane-A synthase (Tbxas1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Thromboxane-A synthase (Tbxas1), Recombinant Protein
Full Product Name
Recombinant Rat Thromboxane-A synthase (Tbxas1)
Product Synonym Gene Name
Tbxas1; Cyp5, Cyp5a1
Product Synonym Names
Recombinant Thromboxane-A synthase (Tbxas1); Thromboxane-A synthase; TXA synthase; TXS EC= 5.3.99.5; Cytochrome P450 5A1
Sequence
MEVLGLLKFE VSGTVVTVTL SVVLLALLKW YSTSAFSRLR KLGIRHPEPS PFVGNLMFFR QGFWESHLEL RERYGPLCGY YLGRRMYIVI SDPDMIKEVL VENFSNFSNR MASGLEPKLI ADSVLMLRDR RWEEVRGALM SAFSPEKLNE MTPLISQACE LLLSHLKHSA ASGDAFDIQR CYCCFTTNVV ASVAFGIEVN SQDAPEDPFV QHCQRVFAFS TPRPLLALIL SFPSIMVPLA RILPNKNRDE LNGFFNTLIR NVIALRDKQT AEERRGDFLQ MVLDAQRSMS SVGVEAFDMV TEALSSAECM GDPPQRCHPT STAKPLTVDE IAGQAFLFLI AGHEITTNTL SFITYLLATH PECQERLLKE VDLFMEKHPA PEYCNLQEGL PYLDMVVAET LRMYPPAFRF TREAAQDCEV LGQHIPAGSV LEIAVGALHH DPEHWPNPET FDPERFTAEA RLQQKPFTYL PFGAGPRSCL GVRLGLLVVK LTLLQVLHKF RFEACPETQV PLQLESKSAL CPKNGVYVKI VSR
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
59,974 Da
Sequence Positions
1-533
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 4; NC_005103.3 (66481264..66651601). Location: 4q21-q22
3D Structure
ModBase 3D Structure for P49430
Species
Rattus norvegicus (Rat)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Tbxas1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Tbxas1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
thromboxane-A synthase
NCBI Official Synonym Full Names
thromboxane A synthase 1, platelet
NCBI Official Symbol
Tbxas1
UniProt Protein Name
Thromboxane-A synthase
UniProt Synonym Protein Names
Cytochrome P450 5A1
UniProt Gene Name
Tbxas1
UniProt Synonym Gene Names
Cyp5; Cyp5a1; TXA synthase; TXS
UniProt Entry Name
THAS_RAT
NCBI Protein Information
thromboxane-A synthase; TXS; TXA synthase; cytochrome P450 5A1; ThromboxA ane synthase 1

NCBI Summary for Tbxas1

catalyzes the conversion of prostaglandin H2 into thromboxane A2; mRNA expression increases in a model of hydronephrotic kidney; may play a role in response to injury [RGD, Feb 2006]

UniProt Comments for Tbxas1

Catalytic activity: (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-9-alpha,11-alpha-epoxy-15-hydroxythromboxa-5,13-dienoate.

Cofactor: Heme group.

Subunit structure: Monomer

By similarity.

Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein

By similarity.

Sequence similarities: Belongs to the cytochrome P450 family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with Tbxas1 recombinant protein

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